Assessment of Structural Intolerance and Durability
General Structure Information 3ii6 XRCC4 structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. 2.4Å AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 Variant Set Distributions Mapped Variants
General Structure Information 3ii6 XRCC4 structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. 2.4Å AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 Variant Set Distributions Mapped Variants
General Structure Information 3ii6 XRCC4 structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. 2.4Å AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 Variant Set Distributions Mapped Variants
General Structure Information 3ii6 XRCC4 structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. 2.4Å AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 Variant Set Distributions Mapped Variants
General Structure Information 3ii6 XRCC4 structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. 2.4Å AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 Variant Set Distributions Mapped Variants
General Structure Information 3ii6 XRCC4 structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. 2.4Å AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 Variant Set Distributions Mapped Variants
General Structure Information 4jol RUNX1T1 complex structure of aml1-eto nhr2 domain with heb fragment 2.91Å AUTH X.J.SUN,Z.WANG,L.WANG,Y.JIANG,N.KOST,T.D.SOONG,W.Y.CHEN,AUTH 2 Z.TANG,T.NAKADAI,O.ELEMENTO,W.FISCHLE,A.MELNICK,D.J.PATEL,AUTH 3 S.D.NIMER,R.G.ROEDERTITL A STABLE TRANSCRIPTION FACTOR COMPLEX NUCLEATED BYTITL 2 OLIGOMERIC AML1-ETO CONTROLS LEUKAEMOGENESIS.REF NATURE V. 500 93 2013REFN ISSN 0028-0836PMID 23812588DOI 10.1038/NATURE12287 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 4a11 ERCC8 structure of the hsddb1-hscsa complex 3.31Å AUTH E.S.FISCHER,A.SCRIMA,K.BOHM,S.MATSUMOTO,G.M.LINGARAJU,AUTH 2 M.FATY,T.YASUDA,S.CAVADINI,M.WAKASUGI,F.HANAOKA,S.IWAI,AUTH 3 H.GUT,K.SUGASAWA,N.H.THOMATITL THE MOLECULAR BASIS OF CRL4(DDB2/CSA) UBIQUITIN LIGASETITL 2 ARCHITECTURE, TARGETING, AND ACTIVATION.REF CELL(CAMBRIDGE,MASS.) V. 147 1024 2011REFN ISSN 0092-8674PMID 22118460DOI 10.1016/J.CELL.2011.10.035 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3tuo SATB1 crystal structure of n-terminal domain of dna-binding protein satb1 1.7Å AUTH Z.WANG,X.YANG,X.CHU,J.ZHANG,H.ZHOU,Y.SHEN,J.LONGTITL THE STRUCTURAL BASIS FOR THE OLIGOMERIZATION OF THETITL 2 N-TERMINAL DOMAIN OF SATB1REF NUCLEIC ACIDS RES. V. 40 4193 2012REFN ISSN 0305-1048PMID 22241778DOI 10.1093/NAR/GKR1284 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 3q90 G3BP1 crystal structure of the ntf2 domain of ras gtpase-activating protein- binding protein 1 1.7Å AUTH M.WELIN,L.TRESAUGUES,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,T.EKBLAD,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,I.JOHANSSON,T.KARLBERG,S.KOL,T.KOTENYOVA,AUTH 4 E.KOUZNETSOVA,M.MOCHE,T.NYMAN,C.PERSSON,H.SCHULER,P.SCHUTZ,AUTH 5 M.I.SIPONEN,A.G.THORSELL,S.VAN DER BERG,E.WAHLBERG,AUTH 6 J.WEIGELT,P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE NTF2 DOMAIN OF RASTITL 2 GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis […]