Assessment of Structural Intolerance and Durability
General Structure Information 2mam ARID4A solution structure of the interdigitated double tudor domain of rbbp1 -1.0Å AUTH W.GONG,J.WANG,S.PERRETT,Y.FENGTITL RETINOBLASTOMA-BINDING PROTEIN 1 HAS AN INTERDIGITATEDTITL 2 DOUBLE TUDOR DOMAIN WITH DNA-BINDING ACTIVITY.REF J.BIOL.CHEM. 2013REFN ESSN 1083-351XPMID 24379399DOI 10.1074/JBC.M113.501940 Variant Set Distributions Mapped Variants
General Structure Information 1d4u XPA interactions of human nucleotide excision repair protein xpa with rpa70 and dna: chemical shift mapping and 15n nmr relaxation studies -1.0Å AUTH G.W.BUCHKO,G.W.DAUGHDRILL,R.DE LORIMIER,K.RAO B,AUTH 2 N.G.ISERN,J.M.LINGBECK,J.S.TAYLOR,M.S.WOLD,AUTH 3 M.GOCHIN,L.D.SPICER,D.F.LOWRY,M.A.KENNEDYTITL INTERACTIONS OF HUMAN NUCLEOTIDE EXCISION REPAIRTITL 2 PROTEIN XPA WITH DNA AND RPA70 DELTA C327:TITL 3 CHEMICAL SHIFT MAPPING AND 15N […]
General Structure Information 2d8m XRCC1 solution structure of the first brct domain of dna-repair protein xrcc1 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST BRCT DOMAIN OFTITL 2 DNA-REPAIR PROTEIN XRCC1REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1l8z UBTF solution structure of hmg box 5 in human upstream binding factor -1.0Å AUTH W.YANG,Y.XU,J.WU,W.ZENG,Y.SHITITL SOLUTION STRUCTURE AND DNA BINDING PROPERTY OF THETITL 2 FIFTH HMG BOX DOMAIN IN COMPARISON WITH THE FIRSTTITL 3 HMG BOX DOMAIN IN HUMAN UPSTREAM BINDING FACTORREF BIOCHEMISTRY V. 42 1930 2003REFN ISSN 0006-2960PMID 12590579DOI 10.1021/BI026372X […]
General Structure Information 1k99 UBTF solution structure of the first hmg box in human upstream binding factor -1.0Å AUTH Y.XU,W.YANG,J.WU,Y.SHITITL SOLUTION STRUCTURE OF THE FIRST HMG BOX DOMAIN INTITL 2 HUMAN UPSTREAM BINDING FACTOR.REF BIOCHEMISTRY V. 41 5415 2002REFN ISSN 0006-2960PMID 11969401DOI 10.1021/BI015977A Variant Set Distributions Mapped Variants
General Structure Information 1cdz XRCC1 brct domain from dna-repair protein xrcc1 3.2Å AUTH X.ZHANG,S.MORERA,P.A.BATES,P.C.WHITEHEAD,AUTH 2 A.I.COFFER,K.HAINBUCHER,R.A.NASH,M.J.STERNBERG,AUTH 3 T.LINDAHL,P.S.FREEMONTTITL STRUCTURE OF AN XRCC1 BRCT DOMAIN: A NEWTITL 2 PROTEIN-PROTEIN INTERACTION MODULE.REF EMBO J. V. 17 6404 1998REFN ISSN 0261-4189PMID 9799248DOI 10.1093/EMBOJ/17.21.6404 Variant Set Distributions Mapped Variants
General Structure Information 1rw2 XRCC5 three-dimensional structure of ku80 ctd -1.0Å AUTH Z.ZHANG,W.HU,L.CANO,T.D.LEE,D.J.CHEN,Y.CHENTITL SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OFTITL 2 KU80 SUGGESTS IMPORTANT SITES FOR PROTEIN-PROTEINTITL 3 INTERACTIONS.REF STRUCTURE V. 12 495 2004REFN ISSN 0969-2126PMID 15016365DOI 10.1016/J.STR.2004.02.007 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1jeq XRCC6 crystal structure of the ku heterodimer 2.7Å AUTH J.R.WALKER,R.A.CORPINA,J.GOLDBERGTITL STRUCTURE OF THE KU HETERODIMER BOUND TO DNA ANDTITL 2 ITS IMPLICATIONS FOR DOUBLE-STRAND BREAK REPAIR.REF NATURE V. 412 607 2001REFN ISSN 0028-0836PMID 11493912DOI 10.1038/35088000 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4dqy PARP1 structure of human parp-1 bound to a dna double strand break 3.25Å AUTH M.F.LANGELIER,J.L.PLANCK,S.ROY,J.M.PASCALTITL STRUCTURAL BASIS FOR DNA DAMAGE-DEPENDENTTITL 2 POLY(ADP-RIBOSYL)ATION BY HUMAN PARP-1.REF SCIENCE V. 336 728 2012REFN ISSN 0036-8075PMID 22582261DOI 10.1126/SCIENCE.1216338 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2yrq HMGB1 solution structure of the tandem hmg box domain from human high mobility group protein b1 -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE TANDEM HMG BOX DOMAINTITL 2 FROM HUMAN HIGH MOBILITY GROUP PROTEIN B1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants