General Structure Information
| PDB ID | 2d8m |
| HGNC Gene Label(s) | XRCC1 |
| Structure Name | solution structure of the first brct domain of dna-repair protein xrcc1 |
| Resolution | -1.0Å |
| Reference | AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST BRCT DOMAIN OFTITL 2 DNA-REPAIR PROTEIN XRCC1REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 116 |
| Number Of SNVs | 33 |
| Number Of Permutations | 13986 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.013 |
| p-value | 0.261 |
COSMIC
| Number Of Residues | 116 |
| Number Of SNVs | 3 |
| Number Of Permutations | 108 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.333 |
| p-value | 0.633 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 33 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.358 |
| p-value | 0.475 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
