General Structure Information 4hzs TNK2 crystal structure of ack1 kinase domain with c-terminal sh3 domain 3.23Å AUTH K.S.GAJIWALA,K.MAEGLEY,R.FERRE,Y.A.HE,X.YUTITL ACK1: ACTIVATION AND REGULATION BY ALLOSTERY.REF PLOS ONE V. 8 53994 2013REFN ESSN 1932-6203PMID 23342057DOI 10.1371/JOURNAL.PONE.0053994 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1rhf TYRO3 crystal structure of human tyro3-d1d2 1.96Å AUTH C.HEIRING,B.DAHLBACK,Y.A.MULLERTITL LIGAND RECOGNITION AND HOMOPHILIC INTERACTIONS IN TYRO3:TITL 2 STRUCTURAL INSIGHTS INTO THE AXL/TYRO3 RECEPTOR TYROSINETITL 3 KINASE FAMILY.REF J.BIOL.CHEM. V. 279 6952 2004REFN ISSN 0021-9258PMID 14623883DOI 10.1074/JBC.M311750200 Variant Set Distributions Mapped Variants
General Structure Information 3ks9 GRM1 metabotropic glutamate receptor mglur1 complexed with ly341495 antagonist 1.9Å AUTH E.DOBROVETSKY,G.KHUTORESKAYA,A.SEITOVA,D.COSSAR,A.M.EDWARDS,AUTH 2 C.H.ARROWSMITH,C.BOUNTRA,J.WEIGELT,A.BOCHKAREVTITL METABOTROPIC GLUTAMATE RECEPTOR MGLUR1 COMPLEXED WITHTITL 2 LY341495 ANTAGONISTREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3lmk GRM5 ligand binding domain of metabotropoc glutamate receptor mglur5 complexed with glutamate 2.44Å AUTH E.DOBROVETSKY,G.KHUTORESKAYA,A.SEITOVA,D.COSSAR,A.M.EDWARDS,AUTH 2 C.H.ARROWSMITH,C.BOUNTRA,J.WEIGELT,A.BOCHKAREVTITL METABOTROPIC GLUTAMATE RECEPTOR MGLUR5 COMPLEXED WITHTITL 2 GLUTAMATEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4bsj FLT4 crystal structure of vegfr-3 extracellular domains d4-5 2.5Å AUTH V.-M.LEPPANEN,D.TVOROGOV,K.KISKO,A.E.PROTA,M.JELTSCH,AUTH 2 A.ANISIMOV,S.MARKOVIC-MUELLER,E.STUTTFELD,K.N.GOLDIE,AUTH 3 K.BALLMER-HOFER,K.ALITALOTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO VEGFR-3 LIGANDTITL 2 BINDING AND ACTIVATIONREF PROC.NATL.ACAD.SCI.USA V. 110 12960 2013REFN ISSN 0027-8424PMID 23878260DOI 10.1073/PNAS.1301415110 Variant Set Distributions Mapped Variants
General Structure Information 1f3u GTF2F1 crystal structure of the rap30/74 interaction domains of human tfiif 1.7Å AUTH F.GAISER,S.TAN,T.J.RICHMONDTITL NOVEL DIMERIZATION FOLD OF RAP30/RAP74 IN HUMANTITL 2 TFIIF AT 1.7 A RESOLUTION.REF J.MOL.BIOL. V. 302 1119 2000REFN ISSN 0022-2836PMID 11183778DOI 10.1006/JMBI.2000.4110 Variant Set Distributions Mapped Variants
General Structure Information 2e9w KITLG crystal structure of the extracellular domain of kit in complex with stem cell factor (scf) 3.5Å AUTH S.YUZAWA,Y.OPATOWSKY,Z.ZHANG,V.MANDIYAN,I.LAX,J.SCHLESSINGERTITL STRUCTURAL BASIS FOR ACTIVATION OF THE RECEPTOR TYROSINETITL 2 KINASE KIT BY STEM CELL FACTORREF CELL(CAMBRIDGE,MASS.) V. 130 323 2007REFN ISSN 0092-8674PMID 17662946DOI 10.1016/J.CELL.2007.05.055 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 1cvs FGFR1 crystal structure of a dimeric fgf2-fgfr1 complex 2.8Å AUTH A.N.PLOTNIKOV,J.SCHLESSINGER,S.R.HUBBARD,AUTH 2 M.MOHAMMADITITL STRUCTURAL BASIS FOR FGF RECEPTOR DIMERIZATION ANDTITL 2 ACTIVATION.REF CELL(CAMBRIDGE,MASS.) V. 98 641 1999REFN ISSN 0092-8674PMID 10490103DOI 10.1016/S0092-8674(00)80051-3 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2e9w KIT crystal structure of the extracellular domain of kit in complex with stem cell factor (scf) 3.5Å AUTH S.YUZAWA,Y.OPATOWSKY,Z.ZHANG,V.MANDIYAN,I.LAX,J.SCHLESSINGERTITL STRUCTURAL BASIS FOR ACTIVATION OF THE RECEPTOR TYROSINETITL 2 KINASE KIT BY STEM CELL FACTORREF CELL(CAMBRIDGE,MASS.) V. 130 323 2007REFN ISSN 0092-8674PMID 17662946DOI 10.1016/J.CELL.2007.05.055 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2dh3 SLC3A2 crystal structure of human ed-4f2hc 2.8Å AUTH J.FORT,L.R.DE LA BALLINA,H.E.BURGHARDT,C.FERRER-COSTA,AUTH 2 J.TURNAY,C.FERRER-ORTA,I.USON,A.ZORZANO,J.FERNANDEZ-RECIO,AUTH 3 M.OROZCO,M.A.LIZARBE,I.FITA,M.PALACINTITL THE STRUCTURE OF HUMAN 4F2HC ECTODOMAIN PROVIDES A MODEL FORTITL 2 HOMODIMERIZATION AND ELECTROSTATIC INTERACTION WITH PLASMATITL 3 MEMBRANE.REF J.BIOL.CHEM. V. 282 31444 2007REFN ISSN 0021-9258PMID 17724034DOI 10.1074/JBC.M704524200 Variant Set Distributions Ripley’s K Analysis Plots Variant […]