Assessment of Structural Intolerance and Durability
General Structure Information 2qa5 SEPT2 crystal structure of sept2 g-domain 3.4Å AUTH M.SIRAJUDDIN,M.FARKASOVSKY,F.HAUER,D.KUHLMANN,AUTH 2 I.G.MACARA,M.WEYAND,H.STARK,A.WITTINGHOFERTITL STRUCTURAL INSIGHT INTO FILAMENT FORMATION BYTITL 2 MAMMALIAN SEPTINS.REF NATURE V. 449 311 2007REFN ISSN 0028-0836PMID 17637674DOI 10.1038/NATURE06052 Variant Set Distributions Mapped Variants
General Structure Information 2qa5 SEPT2 crystal structure of sept2 g-domain 3.4Å AUTH M.SIRAJUDDIN,M.FARKASOVSKY,F.HAUER,D.KUHLMANN,AUTH 2 I.G.MACARA,M.WEYAND,H.STARK,A.WITTINGHOFERTITL STRUCTURAL INSIGHT INTO FILAMENT FORMATION BYTITL 2 MAMMALIAN SEPTINS.REF NATURE V. 449 311 2007REFN ISSN 0028-0836PMID 17637674DOI 10.1038/NATURE06052 Variant Set Distributions Mapped Variants
General Structure Information 1nrv GRB10 crystal structure of the sh2 domain of grb10 1.65Å AUTH E.G.STEIN,R.GHIRLANDO,S.R.HUBBARDTITL STRUCTURAL BASIS FOR DIMERIZATION OF THE GRB10 SRCTITL 2 HOMOLOGY 2 DOMAIN. IMPLICATIONS FOR LIGANDTITL 3 SPECIFICITY.REF J.BIOL.CHEM. V. 278 13257 2003REFN ISSN 0021-9258PMID 12551896DOI 10.1074/JBC.M212026200 Variant Set Distributions Mapped Variants
General Structure Information 2v64 MAD2L1 crystallographic structure of the conformational dimer of the spindle assembly checkpoint protein mad2. 2.9Å AUTH M.MAPELLI,L.MASSIMILIANO,S.SANTAGUIDA,A.MUSACCHIOTITL THE MAD2 CONFORMATIONAL DIMER: STRUCTURE ANDTITL 2 IMPLICATIONS FOR THE SPINDLE ASSEMBLY CHECKPOINTREF CELL(CAMBRIDGE,MASS.) V. 131 730 2007REFN ISSN 0092-8674PMID 18022367DOI 10.1016/J.CELL.2007.08.049 Variant Set Distributions Mapped Variants
General Structure Information 2v4m GFPT1 the isomerase domain of human glutamine-fructose-6- phosphate transaminase 1 (gfpt1) in complex with fructose 6-phosphate 2.29Å AUTH M.MOCHE,L.LEHTIO,J.ANDERSSON,C.H.ARROWSMITH,AUTH 2 H.BERGLUND,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,AUTH 4 A.JOHANSSON,I.JOHANSSON,T.KARLBERG,T.KOTENYOVA,AUTH 5 M.E.NILSSON,T.NYMAN,C.PERSSON,J.SAGEMARK,AUTH 6 S.SVENSSON,H.SCHUELER,A.G.THORSELL,L.TRESAUGUES,AUTH 7 J.UPPENBERG,S.VAN DEN BERG,M.WELIN,M.WISNIEWSKA,AUTH 8 J.WEIGELT,P.NORDLUND,M.WIKSTROMTITL THE ISOMERASE DOMAIN OF HUMAN GFPT1 IN COMPLEXTITL 2 WITH FRUCTOSE 6-PHOSPHATEREF TO BE PUBLISHEDREFN Variant […]
General Structure Information 2v4m GFPT1 the isomerase domain of human glutamine-fructose-6- phosphate transaminase 1 (gfpt1) in complex with fructose 6-phosphate 2.29Å AUTH M.MOCHE,L.LEHTIO,J.ANDERSSON,C.H.ARROWSMITH,AUTH 2 H.BERGLUND,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,AUTH 4 A.JOHANSSON,I.JOHANSSON,T.KARLBERG,T.KOTENYOVA,AUTH 5 M.E.NILSSON,T.NYMAN,C.PERSSON,J.SAGEMARK,AUTH 6 S.SVENSSON,H.SCHUELER,A.G.THORSELL,L.TRESAUGUES,AUTH 7 J.UPPENBERG,S.VAN DEN BERG,M.WELIN,M.WISNIEWSKA,AUTH 8 J.WEIGELT,P.NORDLUND,M.WIKSTROMTITL THE ISOMERASE DOMAIN OF HUMAN GFPT1 IN COMPLEXTITL 2 WITH FRUCTOSE 6-PHOSPHATEREF TO BE PUBLISHEDREFN Variant […]
General Structure Information 2v4m GFPT1 the isomerase domain of human glutamine-fructose-6- phosphate transaminase 1 (gfpt1) in complex with fructose 6-phosphate 2.29Å AUTH M.MOCHE,L.LEHTIO,J.ANDERSSON,C.H.ARROWSMITH,AUTH 2 H.BERGLUND,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,AUTH 4 A.JOHANSSON,I.JOHANSSON,T.KARLBERG,T.KOTENYOVA,AUTH 5 M.E.NILSSON,T.NYMAN,C.PERSSON,J.SAGEMARK,AUTH 6 S.SVENSSON,H.SCHUELER,A.G.THORSELL,L.TRESAUGUES,AUTH 7 J.UPPENBERG,S.VAN DEN BERG,M.WELIN,M.WISNIEWSKA,AUTH 8 J.WEIGELT,P.NORDLUND,M.WIKSTROMTITL THE ISOMERASE DOMAIN OF HUMAN GFPT1 IN COMPLEXTITL 2 WITH FRUCTOSE 6-PHOSPHATEREF TO BE PUBLISHEDREFN Variant […]
General Structure Information 2v64 MAD2L1 crystallographic structure of the conformational dimer of the spindle assembly checkpoint protein mad2. 2.9Å AUTH M.MAPELLI,L.MASSIMILIANO,S.SANTAGUIDA,A.MUSACCHIOTITL THE MAD2 CONFORMATIONAL DIMER: STRUCTURE ANDTITL 2 IMPLICATIONS FOR THE SPINDLE ASSEMBLY CHECKPOINTREF CELL(CAMBRIDGE,MASS.) V. 131 730 2007REFN ISSN 0092-8674PMID 18022367DOI 10.1016/J.CELL.2007.08.049 Variant Set Distributions Mapped Variants
General Structure Information 2v4m GFPT1 the isomerase domain of human glutamine-fructose-6- phosphate transaminase 1 (gfpt1) in complex with fructose 6-phosphate 2.29Å AUTH M.MOCHE,L.LEHTIO,J.ANDERSSON,C.H.ARROWSMITH,AUTH 2 H.BERGLUND,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,AUTH 4 A.JOHANSSON,I.JOHANSSON,T.KARLBERG,T.KOTENYOVA,AUTH 5 M.E.NILSSON,T.NYMAN,C.PERSSON,J.SAGEMARK,AUTH 6 S.SVENSSON,H.SCHUELER,A.G.THORSELL,L.TRESAUGUES,AUTH 7 J.UPPENBERG,S.VAN DEN BERG,M.WELIN,M.WISNIEWSKA,AUTH 8 J.WEIGELT,P.NORDLUND,M.WIKSTROMTITL THE ISOMERASE DOMAIN OF HUMAN GFPT1 IN COMPLEXTITL 2 WITH FRUCTOSE 6-PHOSPHATEREF TO BE PUBLISHEDREFN Variant […]
General Structure Information 2hci CCL20 structure of human mip-3a chemokine 1.81Å AUTH Z.A.MALIK,B.F.TACKTITL STRUCTURE OF HUMAN MIP-3ALPHA CHEMOKINE.REF ACTA CRYSTALLOGR.,SECT.F V. 62 631 2006REFN ESSN 1744-3091PMID 16820679DOI 10.1107/S1744309106006890 Variant Set Distributions Mapped Variants