General Structure Information 3t9l USP15 structure of n-terminal dusp-ubl domains of human usp15 1.5Å AUTH S.HARPER,T.M.BESONG,J.EMSLEY,D.J.SCOTT,I.DREVENYTITL STRUCTURE OF THE USP15 N-TERMINAL DOMAINS: A BETA-HAIRPINTITL 2 MEDIATES CLOSE ASSOCIATION BETWEEN THE DUSP AND UBL DOMAINSREF BIOCHEMISTRY V. 50 7995 2011REFN ISSN 0006-2960PMID 21848306DOI 10.1021/BI200726E Variant Set Distributions Mapped Variants
General Structure Information 3zrh ZRANB1 crystal structure of the lys29, lys33-linkage-specific trabid otu deubiquitinase domain reveals an ankyrin-repeat ubiquitin binding domain (ankubd) 2.23Å AUTH J.D.F.LICCHESI,J.MIESZCZANEK,T.E.T.MEVISSEN,T.J.RUTHERFORD,AUTH 2 M.AKUTSU,S.VIRDEE,F.E.OUALID,J.W.CHIN,H.OVAA,M.BIENZ,AUTH 3 D.KOMANDERTITL AN ANKYRIN-REPEAT UBIQUITIN-BINDING DOMAIN DETERMINESTITL 2 TRABIDS SPECIFICITY FOR ATYPICAL UBIQUITIN CHAINS.REF NAT.STRUCT.MOL.BIOL. V. 19 62 2011REFN ISSN 1545-9993PMID 22157957DOI 10.1038/NSMB.2169 Variant Set Distributions Ripley’s K […]
General Structure Information 1whl CYLD solution structure of the 1st cap-gly domain in human cylindromatosis tumor suppressor cyld -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 1ST CAP-GLY DOMAIN INTITL 2 HUMAN CYLINDROMATOSIS TUMOR SUPPRESSOR CYLDREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2vhf CYLD structure of the cyld usp domain 2.8Å AUTH D.KOMANDER,C.J.LORD,H.SCHEEL,S.SWIFT,K.HOFMANN,AUTH 2 A.ASHWORTH,D.BARFORDTITL THE STRUCTURE OF THE CYLD USP DOMAIN EXPLAINS ITSTITL 2 SPECIFICITY FOR LYS63-LINKED POLYUBIQUITIN ANDTITL 3 REVEALS A B-BOX MODULEREF MOL.CELL.BIOL. V. 29 451 2008REFN ISSN 0270-7306PMID 18313383DOI 10.1016/J.MOLCEL.2007.12.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1whm CYLD solution structure of the 2nd cap-gly domain in human cylindromatosis tumor suppressor cyld -1.0Å AUTH K.SAITOK,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 2ND CAP-GLY DOMAIN INTITL 2 HUMAN CYLINDROMATOSIS TUMOR SUPPRESSOR CYLDREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2f1z USP7 crystal structure of hausp 3.2Å AUTH M.HU,L.GU,M.LI,P.D.JEFFREY,W.GU,Y.SHITITL STRUCTURAL BASIS OF COMPETITIVE RECOGNITION OF P53TITL 2 AND MDM2 BY HAUSP/USP7: IMPLICATIONS FOR THETITL 3 REGULATION OF THE P53-MDM2 PATHWAY.REF PLOS BIOL. V. 4 E27 2006REFN ISSN 1544-9173PMID 16402859DOI 10.1371/JOURNAL.PBIO.0040027 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2ayn USP14 structure of usp14, a proteasome-associated deubiquitinating enzyme 3.2Å AUTH M.HU,P.LI,L.SONG,P.D.JEFFREY,T.A.CHENOVA,AUTH 2 K.D.WILKINSON,R.E.COHEN,Y.SHITITL STRUCTURE AND MECHANISMS OF THETITL 2 PROTEASOME-ASSOCIATED DEUBIQUITINATING ENZYMETITL 3 USP14.REF EMBO J. V. 24 3747 2005REFN ISSN 0261-4189PMID 16211010DOI 10.1038/SJ.EMBOJ.7600832 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3n3k USP8 the catalytic domain of usp8 in complex with a usp8 specific inhibitor 2.6Å AUTH A.ERNST,G.AVVAKUMOV,J.TONG,Y.FAN,Y.ZHAO,P.ALBERTS,A.PERSAUD,AUTH 2 J.R.WALKER,A.M.NECULAI,D.NECULAI,A.VOROBYOV,P.GARG,L.BEATTY,AUTH 3 P.K.CHAN,Y.C.JUANG,M.C.LANDRY,C.YEH,E.ZEQIRAJ,K.KARAMBOULAS,AUTH 4 A.ALLALI-HASSANI,M.VEDADI,M.TYERS,J.MOFFAT,F.SICHERI,AUTH 5 L.PELLETIER,D.DUROCHER,B.RAUGHT,D.ROTIN,J.YANG,M.F.MORAN,AUTH 6 S.DHE-PAGANON,S.S.SIDHUTITL A STRATEGY FOR MODULATION OF ENZYMES IN THE UBIQUITINTITL 2 SYSTEM.REF SCIENCE V. 339 590 2013REFN ISSN 0036-8075PMID 23287719DOI 10.1126/SCIENCE.1230161 Variant Set Distributions Ripley’s K […]