Assessment of Structural Intolerance and Durability
General Structure Information 1g2t CCL26 solution structure of eotaxin-3 -1.0Å AUTH J.YE,K.L.MAYER,M.R.MAYER,M.J.STONETITL NMR SOLUTION STRUCTURE AND BACKBONE DYNAMICS OFTITL 2 THE CC CHEMOKINE EOTAXIN-3.REF BIOCHEMISTRY V. 40 7820 2001REFN ISSN 0006-2960PMID 11425309DOI 10.1021/BI010252S Variant Set Distributions Mapped Variants
General Structure Information 2kum CCL27 solution structure of the human chemokine ccl27 -1.0Å AUTH A.L.JANSMA,J.P.KIRKPATRICK,A.R.HSU,T.M.HANDEL,D.NIETLISPACHTITL NMR ANALYSIS OF THE STRUCTURE, DYNAMICS, AND UNIQUETITL 2 OLIGOMERIZATION PROPERTIES OF THE CHEMOKINE CCL27.REF J.BIOL.CHEM. V. 285 14424 2010REFN ISSN 0021-9258PMID 20200157DOI 10.1074/JBC.M109.091108 Variant Set Distributions Mapped Variants
General Structure Information 4doh IL20RA il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4doh IL20 il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3b94 TNFSF18 crystal structure of human gitrl 2.5Å AUTH X.M.SONG,Z.C.ZHOU,M.I.GREENETITL CRYSTAL STRUCTURE OF HUMAN GITRLREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1n1f IL19 crystal structure of human interleukin-19 1.95Å AUTH C.CHANG,E.MAGRACHEVA,S.KOZLOV,S.FONG,G.TOBIN,S.KOTENKO,AUTH 2 A.WLODAWER,A.ZDANOVTITL CRYSTAL STRUCTURE OF INTERLEUKIN-19 DEFINES A NEW SUBFAMILYTITL 2 OF HELICAL CYTOKINESREF J.BIOL.CHEM. V. 278 3308 2003REFN ISSN 0021-9258PMID 12403790DOI 10.1074/JBC.M208602200 Variant Set Distributions Mapped Variants
General Structure Information 2vhf CYLD structure of the cyld usp domain 2.8Å AUTH D.KOMANDER,C.J.LORD,H.SCHEEL,S.SWIFT,K.HOFMANN,AUTH 2 A.ASHWORTH,D.BARFORDTITL THE STRUCTURE OF THE CYLD USP DOMAIN EXPLAINS ITSTITL 2 SPECIFICITY FOR LYS63-LINKED POLYUBIQUITIN ANDTITL 3 REVEALS A B-BOX MODULEREF MOL.CELL.BIOL. V. 29 451 2008REFN ISSN 0270-7306PMID 18313383DOI 10.1016/J.MOLCEL.2007.12.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3duh IL23A structure of interleukin-23 2.3Å AUTH P.J.LUPARDUS,K.C.GARCIATITL THE STRUCTURE OF INTERLEUKIN-23 REVEALS THE MOLECULAR BASISTITL 2 OF P40 SUBUNIT SHARING WITH INTERLEUKIN-12.REF J.MOL.BIOL. V. 382 931 2008REFN ISSN 0022-2836PMID 18680750DOI 10.1016/J.JMB.2008.07.051 Variant Set Distributions Mapped Variants
General Structure Information 3tgx IL21R il-21:il21r complex 2.8Å AUTH O.J.HAMMING,L.KANG,A.SVENSSON,J.L.KARLSEN,H.RAHBEK-NIELSEN,AUTH 2 S.R.PALUDAN,S.A.HJORTH,K.BONDENSGAARD,R.HARTMANNTITL THE CRYSTAL STRUCTURE OF THE INTERLEUKIN 21 RECEPTOR BOUNDTITL 2 TO INTERLEUKIN 21 REVEALS THAT A SUGAR CHAIN INTERACTINGTITL 3 WITH THE WSXWS MOTIF IS AN INTEGRAL PART OF THE INTERLEUKINTITL 4 21 RECEPTOR.REF J.BIOL.CHEM. 2012REFN ESSN 1083-351XPMID 22235133DOI 10.1074/JBC.M111.311084 Variant Set Distributions […]
General Structure Information 3tgx IL21 il-21:il21r complex 2.8Å AUTH O.J.HAMMING,L.KANG,A.SVENSSON,J.L.KARLSEN,H.RAHBEK-NIELSEN,AUTH 2 S.R.PALUDAN,S.A.HJORTH,K.BONDENSGAARD,R.HARTMANNTITL THE CRYSTAL STRUCTURE OF THE INTERLEUKIN 21 RECEPTOR BOUNDTITL 2 TO INTERLEUKIN 21 REVEALS THAT A SUGAR CHAIN INTERACTINGTITL 3 WITH THE WSXWS MOTIF IS AN INTEGRAL PART OF THE INTERLEUKINTITL 4 21 RECEPTOR.REF J.BIOL.CHEM. 2012REFN ESSN 1083-351XPMID 22235133DOI 10.1074/JBC.M111.311084 Variant Set Distributions […]