Assessment of Structural Intolerance and Durability
General Structure Information 4dzo MAD1L1 structure of human mad1 c-terminal domain reveals its involvement in kinetochore targeting 1.76Å AUTH S.KIM,H.SUN,D.R.TOMCHICK,H.YU,X.LUOTITL STRUCTURE OF HUMAN MAD1 C-TERMINAL DOMAIN REVEALS ITSTITL 2 INVOLVEMENT IN KINETOCHORE TARGETING.REF PROC.NATL.ACAD.SCI.USA V. 109 6549 2012REFN ISSN 0027-8424PMID 22493223DOI 10.1073/PNAS.1118210109 Variant Set Distributions Mapped Variants
General Structure Information 3qor NUDC crystal structure of human nuclear migration protein nudc 1.75Å AUTH M.ZHENG,T.CIERPICKI,A.J.BURDETTE,D.UTEPBERGENOV,P.L.JANCZYK,AUTH 2 U.DEREWENDA,P.T.STUKENBERG,K.A.CALDWELL,Z.S.DEREWENDATITL STRUCTURAL FEATURES AND CHAPERONE ACTIVITY OF THE NUDCTITL 2 PROTEIN FAMILY.REF J.MOL.BIOL. V. 409 722 2011REFN ISSN 0022-2836PMID 21530541DOI 10.1016/J.JMB.2011.04.018 Variant Set Distributions Mapped Variants
General Structure Information 2ns2 SPIN1 crystal structure of spindlin1 2.2Å AUTH Q.ZHAO,L.QIN,F.JIANG,B.WU,W.YUE,F.XU,Z.RONG,H.YUAN,AUTH 2 X.XIE,Y.GAO,C.BAI,M.BARTLAM,X.PEI,Z.RAOTITL STRUCTURE OF HUMAN SPINDLIN1. TANDEM TUDOR-LIKETITL 2 DOMAINS FOR CELL CYCLE REGULATIONREF J.BIOL.CHEM. V. 282 647 2007REFN ISSN 0021-9258PMID 17082182DOI 10.1074/JBC.M604029200 Variant Set Distributions Mapped Variants
General Structure Information 1tvg HSPB11 x-ray structure of human pp25 gene product, hspc034. northeast structural genomics target hr1958. 1.6Å AUTH T.A.RAMELOT,S.RAMAN,A.P.KUZIN,R.XIAO,L.C.MA,AUTH 2 T.B.ACTON,J.F.HUNT,G.T.MONTELIONE,D.BAKER,AUTH 3 M.A.KENNEDYTITL IMPROVING NMR PROTEIN STRUCTURE QUALITY BY ROSETTATITL 2 REFINEMENT: A MOLECULAR REPLACEMENT STUDY.REF PROTEINS V. 75 147 2009REFN ISSN 0887-3585PMID 18816799DOI 10.1002/PROT.22229 Variant Set Distributions Mapped Variants
General Structure Information 2eoc PARP3 solution structure of the wgr domain from human poly [adp- ribose] polymerase-3 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE WGR DOMAIN FROM HUMANTITL 2 POLY [ADP-RIBOSE] POLYMERASE-3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1go4 MAD1L1 crystal structure of mad1-mad2 reveals a conserved mad2 binding motif in mad1 and cdc20. 2.05Å AUTH L.SIRONI,M.MAPELLI,S.KNAPP,A.ANTONI,K.T.JEANG,AUTH 2 A.MUSACCHIOTITL CRYSTAL STRUCTURE OF THE TETRAMERIC MAD1-MAD2 CORETITL 2 COMPLEX: IMPLICATIONS OF A SAFETY BELT BINDINGTITL 3 MECHANISM FOR THE SPINDLE CHECKPOINTREF EMBO J. V. 21 2496 2002REFN ISSN 0261-4189PMID 12006501DOI 10.1093/EMBOJ/21.10.2496 […]
General Structure Information 3bin EPB41L3 structure of the dal-1 and tslc1 (372-383) complex 2.3Å AUTH R.D.BUSAM,A.-G.THORSELL,A.FLORES,M.HAMMARSTROM,C.PERSSON,AUTH 2 B.OBRINK,B.M.HALLBERGTITL STRUCTURAL BASIS OF TUMOR SUPPRESSOR IN LUNG CANCER 1TITL 2 (TSLC1) BINDING TO DIFFERENTIALLY EXPRESSED INTITL 3 ADENOCARCINOMA OF THE LUNG (DAL-1/4.1B)REF J.BIOL.CHEM. V. 286 4511 2011REFN ISSN 0021-9258PMID 21131357DOI 10.1074/JBC.M110.174011 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3abd MAD2L2 structure of human rev7 in complex with a human rev3 fragment in a monoclinic crystal 1.9Å AUTH K.HARA,H.HASHIMOTO,Y.MURAKUMO,S.KOBAYASHI,T.KOGAME,S.UNZAI,AUTH 2 S.AKASHI,S.TAKEDA,T.SHIMIZU,M.SATOTITL CRYSTAL STRUCTURE OF HUMAN REV7 IN COMPLEX WITH A HUMAN REV3TITL 2 FRAGMENT AND STRUCTURAL IMPLICATION OF THE INTERACTIONTITL 3 BETWEEN DNA POLYMERASE {ZETA} AND REV1REF J.BIOL.CHEM. V. 285 12299 […]
General Structure Information 3ffl ANAPC7 crystal structure of the n-terminal domain of anaphase-promoting complex subunit 7 2.5Å AUTH D.HAN,K.KIM,Y.KIM,Y.KANG,Y.KIMTITL CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OFTITL 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4f9b DBF4 human cdc7 kinase in complex with dbf4 and pha767491 2.5Å AUTH S.HUGHES,F.ELUSTONDO,A.DI FONZO,F.G.LEROUX,A.C.WONG,AUTH 2 A.P.SNIJDERS,S.J.MATTHEWS,P.CHEREPANOVTITL CRYSTAL STRUCTURE OF HUMAN CDC7 KINASE IN COMPLEX WITH ITSTITL 2 ACTIVATOR DBF4.REF NAT.STRUCT.MOL.BIOL. V. 19 1101 2012REFN ISSN 1545-9993PMID 23064647DOI 10.1038/NSMB.2404 Variant Set Distributions Mapped Variants