General Structure Information
| PDB ID | 1go4 |
| HGNC Gene Label(s) | MAD1L1 |
| Structure Name | crystal structure of mad1-mad2 reveals a conserved mad2 binding motif in mad1 and cdc20. |
| Resolution | 2.05Å |
| Reference | AUTH L.SIRONI,M.MAPELLI,S.KNAPP,A.ANTONI,K.T.JEANG,AUTH 2 A.MUSACCHIOTITL CRYSTAL STRUCTURE OF THE TETRAMERIC MAD1-MAD2 CORETITL 2 COMPLEX: IMPLICATIONS OF A SAFETY BELT BINDINGTITL 3 MECHANISM FOR THE SPINDLE CHECKPOINTREF EMBO J. V. 21 2496 2002REFN ISSN 0261-4189PMID 12006501DOI 10.1093/EMBOJ/21.10.2496 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 93 |
| Number Of SNVs | 35 |
| Number Of Permutations | 23693 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.03 |
| p-value | 0.27 |
COSMIC
| Number Of Residues | 93 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
