Assessment of Structural Intolerance and Durability
General Structure Information 2ab1 AAMDC x-ray structure of gene product from homo sapiens hs.95870 2.59Å AUTH CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS (CESG)TITL X-RAY STRUCTURE OF GENE PRODUCT FROM HOMO SAPIENS HS.95870REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3ote THG1L crystal structure of human trnahis guanylyltransferase (thg1)- native i 2.56Å AUTH S.J.HYDE,B.E.ECKENROTH,B.A.SMITH,W.A.EBERLEY,N.H.HEINTZ,AUTH 2 J.E.JACKMAN,S.DOUBLIETITL TRNAHIS GUANYLYLTRANSFERASE (THG1), A UNIQUE 3-5TITL 2 NUCLEOTIDYL TRANSFERASE, SHARES UNEXPECTED STRUCTURALTITL 3 HOMOLOGY WITH CANONICAL 5-3 DNA POLYMERASES.REF PROC.NATL.ACAD.SCI.USA V. 107 20305 2010REFN ISSN 0027-8424PMID 21059936DOI 10.1073/PNAS.1010436107 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2ohf OLA1 crystal structure of human ola1 in complex with amppcp 2.7Å AUTH R.KOLLER-EICHHORN,T.MARQUARDT,R.GAIL,A.WITTINGHOFER,AUTH 2 D.KOSTREWA,U.KUTAY,C.KAMBACHTITL HUMAN OLA1 DEFINES AN ATPASE SUBFAMILY IN THE OBG FAMILY OFTITL 2 GTP-BINDING PROTEINSREF J.BIOL.CHEM. V. 282 19928 2007REFN ISSN 0021-9258PMID 17430889DOI 10.1074/JBC.M700541200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2d0j B3GAT2 crystal structure of human glcat-s apo form 2.0Å AUTH T.SHIBA,S.KAKUDA,M.ISHIGURO,I.MORITA,S.OKA,AUTH 2 T.KAWASAKI,S.WAKATSUKI,R.KATOTITL CRYSTAL STRUCTURE OF GLCAT-S, A HUMANTITL 2 GLUCURONYLTRANSFERASE, INVOLVED IN THETITL 3 BIOSYNTHESIS OF THE HNK-1 CARBOHYDRATE EPITOPEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2ocb RAB9B crystal structure of human rab9b in complex with a gtp analogue 2.2Å AUTH B.HONG,L.SHEN,J.R.WALKER,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB9B IN COMPLEX WITH ATITL 2 GTP ANALOGUEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1jlj GPHN 1.6 angstrom crystal structure of the human neuroreceptor anchoring and molybdenum cofactor biosynthesis protein gephyrin 1.6Å AUTH G.SCHWARZ,N.SCHRADER,R.R.MENDEL,H.J.HECHT,AUTH 2 H.SCHINDELINTITL CRYSTAL STRUCTURES OF HUMAN GEPHYRIN AND PLANTTITL 2 CNX1 G DOMAINS: COMPARATIVE ANALYSIS ANDTITL 3 FUNCTIONAL IMPLICATIONS.REF J.MOL.BIOL. V. 312 405 2001REFN ISSN 0022-2836PMID 11554796DOI 10.1006/JMBI.2001.4952 Variant Set Distributions Ripley’s […]
General Structure Information 2jbh PRTFDC1 human phosphoribosyl transferase domain containing 1 1.7Å AUTH M.WELIN,L.EGEBLAD,A.JOHANSSON,P.STENMARK,L.WANG,S.FLODIN,AUTH 2 T.NYMAN,L.TRESAUGUES,T.KOTENYOVA,I.JOHANSSON,S.ERIKSSON,AUTH 3 H.EKLUND,P.NORDLUNDTITL STRUCTURAL AND FUNCTIONAL STUDIES OF THE HUMANTITL 2 PHOSPHORIBOSYLTRANSFERASE DOMAIN CONTAINING PROTEIN 1.REF FEBS J. V. 277 4920 2010REFN ISSN 1742-464XPMID 21054786DOI 10.1111/J.1742-4658.2010.07897.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2q4k C11orf68 ensemble refinement of the protein crystal structure of gene product from homo sapiens hs.433573 2.5Å AUTH E.J.LEVIN,D.A.KONDRASHOV,G.E.WESENBERG,G.N.PHILLIPSTITL ENSEMBLE REFINEMENT OF PROTEIN CRYSTAL STRUCTURES:TITL 2 VALIDATION AND APPLICATION.REF STRUCTURE V. 15 1040 2007REFN ISSN 0969-2126PMID 17850744DOI 10.1016/J.STR.2007.06.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3zyi LRRC4 netring2 in complex with ngl2 2.6Å AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNING THROUGHTITL 2 NETRING-NGL INTERACTIONSREF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4fom PVRL3 crystal structure of human nectin-3 full ectodomain (d1-d3) 3.93Å AUTH O.J.HARRISON,J.VENDOME,J.BRASCH,X.JIN,S.HONG,P.S.KATSAMBA,AUTH 2 G.AHLSEN,R.B.TROYANOVSKY,S.M.TROYANOVSKY,B.HONIG,L.SHAPIROTITL NECTIN ECTODOMAIN STRUCTURES REVEAL A CANONICAL ADHESIVETITL 2 INTERFACE.REF NAT.STRUCT.MOL.BIOL. V. 19 906 2012REFN ISSN 1545-9993PMID 22902367DOI 10.1038/NSMB.2366 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants