Assessment of Structural Intolerance and Durability
General Structure Information 1x5x FNDC3A solution structure of the fibronectin type-iii domain of human fibronectin type iii domain containing protein 3 -1.0Å AUTH M.YONEYAMA,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIBRONECTIN TYPE-IIITITL 2 DOMAIN OF HUMAN FIBRONECTIN TYPE III DOMAINTITL 3 CONTAINING PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dk3 HECTD1 solution structure of mib-herc2 domain in hect domain containing protein 1 -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF MIB-HERC2 DOMAIN IN HECTTITL 2 DOMAIN CONTAINING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dhy CUEDC1 solution structure of the cue domain in the human cue domain containing protein 1 (cuedc1) -1.0Å AUTH C.ZHAO,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CUE DOMAIN IN THE HUMANTITL 2 CUE DOMAIN CONTAINING PROTEIN 1 (CUEDC1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wji TDRD3 solution structure of the uba domain of human tudor domain containing protein 3 -1.0Å AUTH Y.O.KAMATARI,N.TOCHIO,T.NAKANISHI,K.MIYAMOTO,H.LI,AUTH 2 N.KOBAYASHI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 3 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE UBA DOMAIN OF HUMANTITL 2 TUDOR DOMAIN CONTAINING PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4fmu SETD2 crystal structure of methyltransferase domain of human set domain- containing protein 2 compound: pr-snf 2.1Å AUTH W.ZHENG,G.IBANEZ,H.WU,G.BLUM,H.ZENG,A.DONG,F.LI,T.HAJIAN,AUTH 2 A.ALLALI-HASSANI,M.F.AMAYA,A.SIARHEYEVA,W.YU,P.J.BROWN,AUTH 3 M.SCHAPIRA,M.VEDADI,J.MIN,M.LUOTITL SINEFUNGIN DERIVATIVES AS INHIBITORS AND STRUCTURE PROBES OFTITL 2 PROTEIN LYSINE METHYLTRANSFERASE SETD2.REF J.AM.CHEM.SOC. V. 134 18004 2012REFN ISSN 0002-7863PMID 23043551DOI 10.1021/JA307060P Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3k1z HDHD3 crystal structure of human haloacid dehalogenase-like hydrolase domain containing 3 (hdhd3) 1.55Å AUTH E.UGOCHUKWU,K.GUO,W.W.YUE,E.PILKA,K.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN HALOACID DEHALOGENASE-LIKETITL 2 HYDROLASE DOMAIN CONTAINING 3 (HDHD3)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3hlt HDHD2 the crystal structure of human haloacid dehalogenase-like hydrolase domain containing 2 (hdhd2) 2.3Å AUTH E.UGOCHUKWU,N.SHAFQAT,W.W.YUE,R.COCKING,J.E.BRAY,AUTH 2 J.R.C.MUNIZ,T.KROJER,F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 3 J.WEIGELT,A.EDWARDS,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE CRYSTAL STRUCTURE OF HUMAN HALOACID DEHALOGENASE-LIKETITL 2 HYDROLASE DOMAIN CONTAINING 2 (HDHD2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3tht ALKBH8 crystal structure and rna binding properties of the rrm/alkb domains in human abh8, an enzyme catalyzing trna hypermodification, northeast structural genomics consortium target hr5601b 3.01Å AUTH C.PASTORE,I.TOPALIDOU,F.FOROUHAR,A.C.YAN,M.LEVY,J.F.HUNTTITL CRYSTAL STRUCTURE AND RNA BINDING PROPERTIES OF THE RNATITL 2 RECOGNITION MOTIF (RRM) AND ALKB DOMAINS IN HUMAN ALKBTITL 3 HOMOLOG 8 (ABH8), […]
General Structure Information 2id5 LINGO1 crystal structure of the lingo-1 ectodomain 2.7Å AUTH L.MOSYAK,A.WOOD,B.DWYER,M.BUDDHA,M.JOHNSON,A.AULABAUGH,AUTH 2 X.ZHONG,E.PRESMAN,S.BENARD,K.KELLEHER,J.WILHELM,M.L.STAHL,AUTH 3 R.KRIZ,Y.GAO,Z.CAO,H.P.LING,M.N.PANGALOS,F.S.WALSH,AUTH 4 W.S.SOMERSTITL THE STRUCTURE OF THE LINGO-1 ECTODOMAIN, A MODULE IMPLICATEDTITL 2 IN CENTRAL NERVOUS SYSTEM REPAIR INHIBITION.REF J.BIOL.CHEM. V. 281 36378 2006REFN ISSN 0021-9258PMID 17005555DOI 10.1074/JBC.M607314200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2dm4 SORL1 solution structure of the second fn3 domain of human sorla/lr11 -1.0Å AUTH T.NAGASHIMA,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND FN3 DOMAIN OFTITL 2 HUMAN SORLA/LR11REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants