Assessment of Structural Intolerance and Durability
General Structure Information 2uur COL9A1 n-terminal nc4 domain of collagen ix 1.8Å AUTH V.-M.LEPPANEN,H.TOSSAVAINEN,P.PERMI,L.LEHTIO,AUTH 2 G.RONNHOLM,A.GOLDMAN,I.KILPELAINEN,T.PIHLAJAMAATITL CRYSTAL STRUCTURE OF THE N-TERMINAL NC4 DOMAIN OFTITL 2 COLLAGEN IX, A ZINC BINDING MEMBER OF THE LAMININ-TITL 3 NEUREXIN-SEX HORMONE BINDING GLOBULIN (LNS) DOMAINTITL 4 FAMILY.REF J.BIOL.CHEM. V. 282 23219 2007REFN ISSN 0021-9258PMID 17553797DOI 10.1074/JBC.M702514200 Variant Set Distributions […]
General Structure Information 1mil SHC1 transforming protein 2.7Å AUTH V.MIKOL,G.BAUMANN,M.G.ZURINI,U.HOMMELTITL CRYSTAL STRUCTURE OF THE SH2 DOMAIN FROM THETITL 2 ADAPTOR PROTEIN SHC: A MODEL FOR PEPTIDE BINDINGTITL 3 BASED ON X-RAY AND NMR DATA.REF J.MOL.BIOL. V. 254 86 1995REFN ISSN 0022-2836PMID 7473762DOI 10.1006/JMBI.1995.0601 Variant Set Distributions Mapped Variants
General Structure Information 2v53 SPARC crystal structure of a sparc-collagen complex 3.2Å AUTH E.HOHENESTER,T.SASAKI,C.GIUDICI,R.W.FARNDALE,AUTH 2 H.P.BACHINGERTITL STRUCTURAL BASIS OF SEQUENCE-SPECIFIC COLLAGENTITL 2 RECOGNITION BY SPARC.REF PROC.NATL.ACAD.SCI.USA V. 105 18273 2008REFN ISSN 0027-8424PMID 19011090DOI 10.1073/PNAS.0808452105 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2wnu C1QA complex between c1q globular heads and heparan sulfate 2.3Å AUTH V.GARLATTI,A.CHOUQUET,T.LUNARDI,R.VIVES,H.PAIDASSI,AUTH 2 H.LORTAT-JACOB,N.M.THIELENS,G.J.ARLAUD,C.GABORIAUDTITL CUTTING EDGE: C1Q BINDS DEOXYRIBOSE AND HEPARANTITL 2 SULFATE THROUGH NEIGHBORING SITES OF ITSTITL 3 RECOGNITION DOMAIN.REF J.IMMUNOL. V. 185 808 2010REFN ISSN 0022-1767PMID 20548024DOI 10.4049/JIMMUNOL.1000184 Variant Set Distributions Mapped Variants
General Structure Information 2wnv C1QC complex between c1q globular heads and deoxyribose 1.25Å AUTH V.GARLATTI,A.CHOUQUET,T.LUNARDI,R.VIVES,H.PAIDASSI,AUTH 2 H.LORTAT-JACOB,N.M.THIELENS,G.J.ARLAUD,C.GABORIAUDTITL CUTTING EDGE: C1Q BINDS DEOXYRIBOSE AND HEPARANTITL 2 SULFATE THROUGH NEIGHBORING SITES OF ITSTITL 3 RECOGNITION DOMAIN.REF J.IMMUNOL. V. 185 808 2010REFN ISSN 0022-1767PMID 20548024DOI 10.4049/JIMMUNOL.1000184 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 2jg8 C1QB crystallographic structure of human c1q globular heads complexed to phosphatidyl-serine 2.05Å AUTH H.PAIDASSI,P.TACNET-DELORME,V.GARLATTI,C.DARNAULT,AUTH 2 B.GHEBREHIWET,C.GABORIAUD,G.J.ARLAUD,P.FRACHETTITL C1Q BINDS PHOSPHATIDYLSERINE AND LIKELY ACTS AS ATITL 2 MULTILIGAND-BRIDGING MOLECULE IN APOPTOTIC CELLTITL 3 RECOGNITION.REF J.IMMUNOL. V. 180 2329 2008REFN ISSN 0022-1767PMID 18250442 Variant Set Distributions Mapped Variants
General Structure Information 2j60 FCN3 h-ficolin complexed to d-fucose 1.8Å AUTH V.GARLATTI,N.BELLOY,L.MARTIN,M.LACROIX,AUTH 2 M.MATSUSHITA,Y.ENDO,T.FUJITA,J.C.FONTECILLA-CAMPS,AUTH 3 G.J.ARLAUD,N.M.THIELENS,C.GABORIAUDTITL STRUCTURAL INSIGHTS INTO THE INNATE IMMUNETITL 2 RECOGNITION SPECIFICITIES OF L- AND H-FICOLINS.REF EMBO J. V. 26 623 2007REFN ISSN 0261-4189PMID 17215869DOI 10.1038/SJ.EMBOJ.7601500 Variant Set Distributions Mapped Variants