General Structure Information
| PDB ID | 2wnv |
| HGNC Gene Label(s) | C1QC |
| Structure Name | complex between c1q globular heads and deoxyribose |
| Resolution | 1.25Å |
| Reference | AUTH V.GARLATTI,A.CHOUQUET,T.LUNARDI,R.VIVES,H.PAIDASSI,AUTH 2 H.LORTAT-JACOB,N.M.THIELENS,G.J.ARLAUD,C.GABORIAUDTITL CUTTING EDGE: C1Q BINDS DEOXYRIBOSE AND HEPARANTITL 2 SULFATE THROUGH NEIGHBORING SITES OF ITSTITL 3 RECOGNITION DOMAIN.REF J.IMMUNOL. V. 185 808 2010REFN ISSN 0022-1767PMID 20548024DOI 10.4049/JIMMUNOL.1000184 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 129 |
| Number Of SNVs | 30 |
| Number Of Permutations | 3480 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.138 |
| p-value | 0.392 |
COSMIC
| Number Of Residues | 129 |
| Number Of SNVs | 6 |
| Number Of Permutations | 671 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.368 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 30 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.149 |
| p-value | 0.727 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
