Assessment of Structural Intolerance and Durability
General Structure Information 3cyy TJP1 the crystal structure of zo-1 pdz2 in complex with the cx43 peptide 2.4Å AUTH J.CHEN,L.PAN,Z.WEI,Y.ZHAO,M.ZHANGTITL DOMAIN-SWAPPED DIMERIZATION OF ZO-1 PDZ2 GENERATES SPECIFICTITL 2 AND REGULATORY CONNEXIN43-BINDING SITESREF EMBO J. V. 27 2113 2008REFN ISSN 0261-4189PMID 18636092DOI 10.1038/EMBOJ.2008.138 Variant Set Distributions Mapped Variants
General Structure Information 2ain MLLT4 solution structure of the af-6 pdz domain complexed with the c-terminal peptide from the bcr protein -1.0Å AUTH Q.CHEN,X.NIU,Y.XU,J.WU,Y.SHITITL SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF THETITL 2 AF-6 PDZ DOMAIN/BCR PEPTIDE COMPLEX.REF PROTEIN SCI. V. 16 1053 2007REFN ISSN 0961-8368PMID 17473018DOI 10.1110/PS.062440607 Variant Set Distributions Mapped Variants
General Structure Information 3sf4 GPSM2 crystal structure of the complex between the conserved cell polarity proteins inscuteable and lgn 2.6Å AUTH S.YUZAWA,S.KAMAKURA,Y.IWAKIRI,J.HAYASE,H.SUMIMOTOTITL STRUCTURAL BASIS FOR INTERACTION BETWEEN THE CONSERVED CELLTITL 2 POLARITY PROTEINS INSCUTEABLE AND LEU-GLY-ASNTITL 3 REPEAT-ENRICHED PROTEIN (LGN)REF PROC.NATL.ACAD.SCI.USA V. 108 19210 2011REFN ISSN 0027-8424PMID 22074847DOI 10.1073/PNAS.1110951108 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1jsg TCL1A crystal structure of p14tcl1, an oncogene product involved in t-cell prolymphocytic leukemia, reveals a novel b- barrel topology 2.5Å AUTH F.HOH,Y.S.YANG,L.GUIGNARD,A.PADILLA,M.H.STERN,AUTH 2 J.M.LHOSTE,H.VAN TILBEURGHTITL CRYSTAL STRUCTURE OF P14TCL1, AN ONCOGENE PRODUCTTITL 2 INVOLVED IN T-CELL PROLYMPHOCYTIC LEUKEMIA,TITL 3 REVEALS A NOVEL BETA-BARREL TOPOLOGY.REF STRUCTURE V. 6 147 1998REFN ISSN 0969-2126PMID […]
General Structure Information 1o7b TNFAIP6 refined solution structure of the human tsg-6 link module -1.0Å AUTH C.D.BLUNDELL,D.MAHONEY,A.ALMOND,P.DEANGELIS,AUTH 2 J.D.KAHMANN,P.TERIETE,A.R.PICKFORD,I.D.CAMPBELL,AUTH 3 A.J.DAYTITL THE LINK MODULE FROM OVULATION- ANDTITL 2 INFLAMMATION-ASSOCIATED PROTEIN TSG-6 CHANGESTITL 3 CONFORMATION ON HYALURONAN BINDINGREF J.BIOL.CHEM. V. 278 49261 2003REFN ISSN 0021-9258PMID 12972412DOI 10.1074/JBC.M309623200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 1dks CKS1B ckshs1: human cyclin dependent kinase subunit, type 1 in complex with phosphate 3.2Å AUTH A.S.ARVAI,Y.BOURNE,M.J.HICKEY,J.A.TAINERTITL CRYSTAL STRUCTURE OF THE HUMAN CELL CYCLE PROTEINTITL 2 CKSHS1: SINGLE DOMAIN FOLD WITH SIMILARITY TOTITL 3 KINASE N-LOBE DOMAIN.REF J.MOL.BIOL. V. 249 835 1995REFN ISSN 0022-2836PMID 7791211DOI 10.1006/JMBI.1995.0341 Variant Set Distributions Mapped Variants
General Structure Information 2npl CXADR nmr structure of card d2 domain -1.0Å AUTH S.JIANG,M.CAFFREYTITL SOLUTION STRUCTURE OF THE COXSACKIEVIRUS ANDTITL 2 ADENOVIRUS RECEPTOR DOMAIN 2REF PROTEIN SCI. V. 16 539 2007REFN ISSN 0961-8368PMID 17322536DOI 10.1110/PS.062643507 Variant Set Distributions Mapped Variants
General Structure Information 1vyh PAFAH1B2 paf-ah holoenzyme: lis1/alfa2 3.4Å AUTH C.TARRICONE,F.PERRINA,S.MONZANI,L.MASSIMILIANO,AUTH 2 M.H.KIM,Z.S.DEREWENDA,S.KNAPP,L.-H.TSAI,A.MUSACCHIOTITL COUPLING PAF SIGNALING TO DYNEIN REGULATION:TITL 2 STRUCTURE OF LIS1 IN COMPLEX WITH PAF-TITL 3 ACETYLHYDROLASE.REF NEURON V. 44 809 2004REFN ISSN 0896-6273PMID 15572112DOI 10.1016/J.NEURON.2004.11.019 Variant Set Distributions Mapped Variants
General Structure Information 2ctj HDLBP solution structure of the 8th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 8TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wyx BCAR1 the crystal structure of the p130cas sh3 domain at 1.1 a resolution 1.14Å AUTH M.WISNIEWSKA,B.BOSSENMAIER,G.GEORGES,F.HESSE,AUTH 2 M.DANGL,K.P.KUNKELE,I.IOANNIDIS,R.HUBER,R.A.ENGHTITL THE 1.1 A RESOLUTION CRYSTAL STRUCTURE OF THETITL 2 P130CAS SH3 DOMAIN AND RAMIFICATIONS FOR LIGANDTITL 3 SELECTIVITYREF J.MOL.BIOL. V. 347 1005 2005REFN ISSN 0022-2836PMID 15784259DOI 10.1016/J.JMB.2005.02.017 Variant Set Distributions Mapped Variants