General Structure Information 3ff3 NAALAD2 the high resolution structure of human glutamate carboxypeptidase iii (gcpiii/naaladase ii) in complex with l-glutamate 1.37Å AUTH K.HLOUCHOVA,C.BARINKA,J.KONVALINKA,J.LUBKOWSKITITL STRUCTURAL INSIGHT INTO THE EVOLUTIONARY AND PHARMACOLOGICTITL 2 HOMOLOGY OF GLUTAMATE CARBOXYPEPTIDASES II AND IIIREF FEBS J. V. 276 4448 2009REFN ISSN 1742-464XPMID 19678840DOI 10.1111/J.1742-4658.2009.07152.X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2boa CPA4 human procarboxypeptidase a4. 2.2Å AUTH R.GARCIA-CASTELLANOS,R.BONET-FIGUEREDO,I.PALLARES,AUTH 2 S.VENTURA,F.X.AVILES,J.VENDRELL,F.X.GOMIS-RUTHTITL DETAILED MOLECULAR COMPARISON BETWEEN THETITL 2 INHIBITION MODE OF A/B-TYPE CARBOXYPEPTIDASES INTITL 3 THE ZYMOGEN STATE AND BY THE ENDOGENOUS INHIBITORTITL 4 LATEXIN.REF CELL.MOL.LIFE SCI. V. 62 1996 2005REFN ISSN 1420-682XPMID 16091843DOI 10.1007/S00018-005-5174-4 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2bo9 LXN human carboxypeptidase a4 in complex with human latexin. 1.6Å AUTH I.PALLARES,R.BONET,R.GARCIA-CASTELLANOS,S.VENTURA,AUTH 2 F.X.AVILES,J.VENDRELL,F.X.GOMIS-RUETHTITL STRUCTURE OF HUMAN CARBOXYPEPTIDASE A4 WITH ITSTITL 2 ENDOGENOUS PROTEIN INHIBITOR, LATEXIN.REF PROC.NATL.ACAD.SCI.USA V. 102 3978 2005REFN ISSN 0027-8424PMID 15738388DOI 10.1073/PNAS.0500678102 Variant Set Distributions Mapped Variants
General Structure Information 3dlj CNDP1 crystal structure of human carnosine dipeptidase 1 2.26Å AUTH E.DOBROVETSKY,A.DONG,A.SEITOVA,H.HE,W.TEMPEL,I.KOZIERADZKI,AUTH 2 C.H.ARROWSMITH,J.WEIGELT,C.BOUNTRA,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 D.COSSARTITL CRYSTAL STRUCTURE OF HUMAN CARNOSINE DIPEPTIDASE 1.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3d68 CPB2 crystal structure of a t325i/t329i/h333y/h335q mutant of thrombin- activatable fibrinolysis inhibitor (tafi-iiyq) 2.8Å AUTH P.F.MARX,T.H.BRONDIJK,T.PLUG,R.A.ROMIJN,W.HEMRIKA,AUTH 2 J.C.M.MEIJERS,E.G.HUIZINGATITL CRYSTAL STRUCTURES OF TAFI ELUCIDATE THE INACTIVATIONTITL 2 MECHANISM OF ACTIVATED TAFI: A NOVEL MECHANISM FOR ENZYMETITL 3 AUTOREGULATIONREF BLOOD V. 112 2803 2008REFN ISSN 0006-4971PMID 18559974DOI 10.1182/BLOOD-2008-03-146001 Variant Set Distributions Ripley’s K […]
General Structure Information 3bxm FOLH1 structure of an inactive mutant of human glutamate carboxypeptidase ii [gcpii(e424a)] in complex with n-acetyl-asp-glu (naag) 1.71Å AUTH V.KLUSAK,C.BARINKA,A.PLECHANOVOVA,P.MLCOCHOVA,J.KONVALINKA,AUTH 2 L.RULISEK,J.LUBKOWSKITITL REACTION MECHANISM OF GLUTAMATE CARBOXYPEPTIDASE II REVEALEDTITL 2 BY MUTAGENESIS, X-RAY CRYSTALLOGRAPHY, AND COMPUTATIONALTITL 3 METHODS.REF BIOCHEMISTRY V. 48 4126 2009REFN ISSN 0006-2960PMID 19301871DOI 10.1021/BI900220S Variant Set Distributions Ripley’s […]
General Structure Information 3bxm FOLH1 structure of an inactive mutant of human glutamate carboxypeptidase ii [gcpii(e424a)] in complex with n-acetyl-asp-glu (naag) 1.71Å AUTH V.KLUSAK,C.BARINKA,A.PLECHANOVOVA,P.MLCOCHOVA,J.KONVALINKA,AUTH 2 L.RULISEK,J.LUBKOWSKITITL REACTION MECHANISM OF GLUTAMATE CARBOXYPEPTIDASE II REVEALEDTITL 2 BY MUTAGENESIS, X-RAY CRYSTALLOGRAPHY, AND COMPUTATIONALTITL 3 METHODS.REF BIOCHEMISTRY V. 48 4126 2009REFN ISSN 0006-2960PMID 19301871DOI 10.1021/BI900220S Variant Set Distributions Ripley’s […]
General Structure Information 3n2z PRCP the structure of human prolylcarboxypeptidase at 2.80 angstroms resolution 2.79Å AUTH S.M.SOISSON,S.B.PATEL,P.D.ABEYWICKREMA,N.J.BRYNE,R.E.DIEHL,AUTH 2 D.L.HALL,R.E.FORD,J.C.REID,K.W.RICKERT,J.M.SHIPMAN,S.SHARMA,AUTH 3 K.J.LUMBTITL STRUCTURAL DEFINITION AND SUBSTRATE SPECIFICITY OF THE S28TITL 2 PROTEASE FAMILY: THE CRYSTAL STRUCTURE OF HUMANTITL 3 PROLYLCARBOXYPEPTIDASE.REF BMC STRUCT.BIOL. V. 10 16 2010REFN ESSN 1472-6807PMID 20540760DOI 10.1186/1472-6807-10-16 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3fju CPA1 ascaris suum carboxypeptidase inhibitor in complex with human carboxypeptidase a1 1.6Å AUTH L.SANGLAS,F.X.AVILES,R.HUBER,F.X.GOMIS-RUTH,J.L.AROLASTITL MAMMALIAN METALLOPEPTIDASE INHIBITION AT THE DEFENSE BARRIERTITL 2 OF ASCARIS PARASITEREF PROC.NATL.ACAD.SCI.USA V. 106 1743 2009REFN ISSN 0027-8424PMID 19179285DOI 10.1073/PNAS.0812623106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1uwy CPM crystal structure of human carboxypeptidase m 3.0Å AUTH D.REVERTER,K.MASKOS,F.TAN,R.SKIDGEL,W.BODETITL CRYSTAL STRUCTURE OF HUMAN CARBOXYPEPTIDASE M, ATITL 2 MEMBRANE-BOUND ENZYME THAT REGULATES PEPTIDETITL 3 HORMONE ACTIVITYREF J.MOL.BIOL. V. 338 257 2004REFN ISSN 0022-2836PMID 15066430DOI 10.1016/J.JMB.2004.02.058 Variant Set Distributions Mapped Variants