General Structure Information 4mjj DOC2A crystal structure of the c2a domain of doc2a 2.0Å AUTH Q.Q.HUANGTITL CRYSTAL STRUCTURE OF THE C2A DOMAIN OF DOC2AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
Assessment of Structural Intolerance and Durability
General Structure Information 4mjj DOC2A crystal structure of the c2a domain of doc2a 2.0Å AUTH Q.Q.HUANGTITL CRYSTAL STRUCTURE OF THE C2A DOMAIN OF DOC2AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3e3r CAPS crystal structure and biochemical characterization of recombinant human calcyphosine delineates a novel ef-hand-containing protein family 2.65Å AUTH H.DONG,X.LI,Z.LOU,X.XU,D.SU,X.ZHOU,W.ZHOU,M.BARTLAM,Z.RAOTITL CRYSTAL-STRUCTURE AND BIOCHEMICAL CHARACTERIZATION OFTITL 2 RECOMBINANT HUMAN CALCYPHOSINE DELINEATES A NOVELTITL 3 EF-HAND-CONTAINING PROTEIN FAMILYREF J.MOL.BIOL. V. 383 455 2008REFN ISSN 0022-2836PMID 18775726DOI 10.1016/J.JMB.2008.08.048 Variant Set Distributions Mapped Variants
General Structure Information 4gnk PLCB3 crystal structure of galphaq in complex with full-length human plcbeta3 4.0Å AUTH A.M.LYON,S.DUTTA,C.A.BOGUTH,G.SKINIOTIS,J.J.TESMERTITL FULL-LENGTH G ALPHA (Q)-PHOSPHOLIPASE C-BETA 3 STRUCTURETITL 2 REVEALS INTERFACES OF THE C-TERMINAL COILED-COIL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 20 355 2013REFN ISSN 1545-9993PMID 23377541DOI 10.1038/NSMB.2497 Variant Set Distributions Mapped Variants
General Structure Information 4gnk PLCB3 crystal structure of galphaq in complex with full-length human plcbeta3 4.0Å AUTH A.M.LYON,S.DUTTA,C.A.BOGUTH,G.SKINIOTIS,J.J.TESMERTITL FULL-LENGTH G ALPHA (Q)-PHOSPHOLIPASE C-BETA 3 STRUCTURETITL 2 REVEALS INTERFACES OF THE C-TERMINAL COILED-COIL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 20 355 2013REFN ISSN 1545-9993PMID 23377541DOI 10.1038/NSMB.2497 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 1j8e LRP1 crystal structure of ligand-binding repeat cr7 from lrp 1.85Å AUTH M.SIMONOVIC,K.DOLMER,W.HUANG,D.K.STRICKLAND,K.VOLZ,AUTH 2 P.G.GETTINSTITL CALCIUM COORDINATION AND PH DEPENDENCE OF THETITL 2 CALCIUM AFFINITY OF LIGAND-BINDING REPEAT CR7 FROMTITL 3 THE LRP. COMPARISON WITH RELATED DOMAINS FROM THETITL 4 LRP AND THE LDL RECEPTOR.REF BIOCHEMISTRY V. 40 15127 2001REFN ISSN 0006-2960PMID […]
General Structure Information 1nud TGM3 role of calcium ions in the activation and activity of the transglutaminase 3 enzyme (3 calciums, active form) 2.7Å AUTH B.AHVAZI,K.M.BOESHANS,W.IDLER,U.BAXA,P.M.STEINERTTITL ROLES OF CALCIUM IONS IN THE ACTIVATION ANDTITL 2 ACTIVITY OF THE TRANSGLUTAMINASE 3 ENZYMEREF J.BIOL.CHEM. V. 278 23834 2003REFN ISSN 0021-9258PMID 12679341DOI 10.1074/JBC.M301162200 Variant Set Distributions Ripley’s K […]
General Structure Information 4hre S100A10 crystal structure of p11/annexin a2 heterotetramer in complex with smarca3 peptide 2.79Å AUTH Y.S.OH,P.GAO,K.W.LEE,I.CEGLIA,J.S.SEO,X.ZHANG,J.H.AHN,AUTH 2 B.T.CHAIT,D.J.PATEL,Y.KIM,P.GREENGARDTITL SMARCA3, A CHROMATIN-REMODELING FACTOR, IS REQUIRED FORTITL 2 P11-DEPENDENT ANTIDEPRESSANT ACTION.REF CELL(CAMBRIDGE,MASS.) V. 152 831 2013REFN ISSN 0092-8674PMID 23415230DOI 10.1016/J.CELL.2013.01.014 Variant Set Distributions Mapped Variants
General Structure Information 1j8e LRP1 crystal structure of ligand-binding repeat cr7 from lrp 1.85Å AUTH M.SIMONOVIC,K.DOLMER,W.HUANG,D.K.STRICKLAND,K.VOLZ,AUTH 2 P.G.GETTINSTITL CALCIUM COORDINATION AND PH DEPENDENCE OF THETITL 2 CALCIUM AFFINITY OF LIGAND-BINDING REPEAT CR7 FROMTITL 3 THE LRP. COMPARISON WITH RELATED DOMAINS FROM THETITL 4 LRP AND THE LDL RECEPTOR.REF BIOCHEMISTRY V. 40 15127 2001REFN ISSN 0006-2960PMID […]
General Structure Information 1nud TGM3 role of calcium ions in the activation and activity of the transglutaminase 3 enzyme (3 calciums, active form) 2.7Å AUTH B.AHVAZI,K.M.BOESHANS,W.IDLER,U.BAXA,P.M.STEINERTTITL ROLES OF CALCIUM IONS IN THE ACTIVATION ANDTITL 2 ACTIVITY OF THE TRANSGLUTAMINASE 3 ENZYMEREF J.BIOL.CHEM. V. 278 23834 2003REFN ISSN 0021-9258PMID 12679341DOI 10.1074/JBC.M301162200 Variant Set Distributions Ripley’s K […]
General Structure Information 4hre S100A10 crystal structure of p11/annexin a2 heterotetramer in complex with smarca3 peptide 2.79Å AUTH Y.S.OH,P.GAO,K.W.LEE,I.CEGLIA,J.S.SEO,X.ZHANG,J.H.AHN,AUTH 2 B.T.CHAIT,D.J.PATEL,Y.KIM,P.GREENGARDTITL SMARCA3, A CHROMATIN-REMODELING FACTOR, IS REQUIRED FORTITL 2 P11-DEPENDENT ANTIDEPRESSANT ACTION.REF CELL(CAMBRIDGE,MASS.) V. 152 831 2013REFN ISSN 0092-8674PMID 23415230DOI 10.1016/J.CELL.2013.01.014 Variant Set Distributions Mapped Variants