Assessment of Structural Intolerance and Durability
General Structure Information 2k6m SVIL solution structure of human supervillin headpiece -1.0Å AUTH J.W.BROWN,D.VARDAR-ULU,C.J.MCKNIGHTTITL HOW TO ARM A SUPERVILLIN: DESIGNING F-ACTIN BINDINGTITL 2 ACTIVITY INTO SUPERVILLIN HEADPIECE.REF J.MOL.BIOL. V. 393 608 2009REFN ISSN 0022-2836PMID 19683541DOI 10.1016/J.JMB.2009.08.018 Variant Set Distributions Mapped Variants
General Structure Information 3edi TLL1 crystal structure of tolloid-like protease 1 (tll-1) protease domain 1.4Å AUTH A.MAC SWEENEY,S.G.PARRADO,D.VINZENZ,A.BERNARDI,AUTH 2 A.HEIN,U.BODENDORF,P.ERBEL,C.LOGEL,B.GERHARTZTITL STRUCTURAL BASIS FOR THE SUBSTRATE SPECIFICITY OFTITL 2 BONE MORPHOGENETIC PROTEIN 1/TOLLOID-LIKETITL 3 METALLOPROTEASESREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1szb MASP2 crystal structure of the human mbl-associated protein 19 (map19) 2.5Å AUTH L.A.GREGORY,N.M.THIELENS,M.MATSUSHITA,R.SORENSEN,AUTH 2 G.J.ARLAUD,J.C.FONTECILLA-CAMPS,C.GABORIAUDTITL THE X-RAY STRUCTURE OF HUMAN MBL-ASSOCIATEDTITL 2 PROTEIN 19 (MAP19) AND ITS INTERACTION SITE WITHTITL 3 MANNAN-BINDING LECTIN AND L-FICOLINREF J.BIOL.CHEM. V. 279 29391 2004REFN ISSN 0021-9258PMID 15117939DOI 10.1074/JBC.M402687200 Variant Set Distributions Mapped Variants
General Structure Information 2vaf CASQ2 crystal structure of human cardiac calsequestrin 3.8Å AUTH E.KIM,B.YOUN,L.KEMPER,C.CAMPBELL,H.MILTING,AUTH 2 M.VARSANYI,C.KANGTITL CHARACTERIZATION OF HUMAN CARDIAC CALSEQUESTRINTITL 2 AND ITS DELETERIOUS MUTANTS.REF J.MOL.BIOL. V. 373 1047 2007REFN ISSN 0022-2836PMID 17881003DOI 10.1016/J.JMB.2007.08.055 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants