Assessment of Structural Intolerance and Durability
General Structure Information 3ff3 NAALAD2 the high resolution structure of human glutamate carboxypeptidase iii (gcpiii/naaladase ii) in complex with l-glutamate 1.37Å AUTH K.HLOUCHOVA,C.BARINKA,J.KONVALINKA,J.LUBKOWSKITITL STRUCTURAL INSIGHT INTO THE EVOLUTIONARY AND PHARMACOLOGICTITL 2 HOMOLOGY OF GLUTAMATE CARBOXYPEPTIDASES II AND IIIREF FEBS J. V. 276 4448 2009REFN ISSN 1742-464XPMID 19678840DOI 10.1111/J.1742-4658.2009.07152.X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3ox6 CABP1 crystal structure of the calcium sensor calcium-binding protein 1 (cabp1) 2.4Å AUTH F.FINDEISEN,D.L.MINORTITL STRUCTURAL BASIS FOR THE DIFFERENTIAL EFFECTS OF CABP1 ANDTITL 2 CALMODULIN ON CA(V)1.2 CALCIUM-DEPENDENT INACTIVATION.REF STRUCTURE V. 18 1617 2010REFN ISSN 0969-2126PMID 21134641DOI 10.1016/J.STR.2010.09.012 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2l5y STIM2 nmr structure of calcium-loaded stim2 ef-sam. -1.0Å AUTH L.ZHENG,P.B.STATHOPULOS,R.SCHINDL,G.Y.LI,C.ROMANIN,M.IKURATITL AUTO-INHIBITORY ROLE OF THE EF-SAM DOMAIN OF STIM PROTEINSTITL 2 IN STORE-OPERATED CALCIUM ENTRY.REF PROC.NATL.ACAD.SCI.USA V. 108 1337 2011REFN ISSN 0027-8424PMID 21217057DOI 10.1073/PNAS.1015125108 Variant Set Distributions Mapped Variants
General Structure Information 2i2r KCNIP1 crystal structure of the kchip1/kv4.3 t1 complex 3.35Å AUTH M.PIOLETTI,F.FINDEISEN,G.L.HURA,D.L.MINOR JR.TITL THREE-DIMENSIONAL STRUCTURE OF THE KCHIP1-KV4.3 T1 COMPLEXTITL 2 REVEALS A CROSS-SHAPED OCTAMERREF NAT.STRUCT.MOL.BIOL. V. 13 987 2006REFN ISSN 1545-9993PMID 17057713DOI 10.1038/NSMB1164 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4msp FKBP14 crystal structure of human peptidyl-prolyl cis-trans isomerase fkbp22 (aka fkbp14) containing two ef-hand motifs 1.9Å AUTH S.P.BOUDKO,Y.ISHIKAWA,J.NIX,M.S.CHAPMAN,H.P.BACHINGERTITL STRUCTURE OF HUMAN PEPTIDYL-PROLYL CIS-TRANS ISOMERASETITL 2 FKBP22 CONTAINING TWO EF-HAND MOTIFS.REF PROTEIN SCI. V. 23 67 2014REFN ISSN 0961-8368PMID 24272907DOI 10.1002/PRO.2391 Variant Set Distributions Mapped Variants
General Structure Information 3n1g BOC crystal structure of dhhn bound to bocfn3 1.9Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Mapped Variants
General Structure Information 4nsc MICU1 crystal structure of cbara1 in the apo-form 3.2Å AUTH L.WANG,X.YANG,S.LI,Z.WANG,Y.LIU,J.FENG,Y.ZHU,Y.SHENTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO MICU1 REGULATION OFTITL 2 MITOCHONDRIAL CALCIUM UPTAKE.REF EMBO J. V. 33 594 2014REFN ISSN 0261-4189PMID 24514027DOI 10.1002/EMBJ.201386523 Variant Set Distributions Mapped Variants
General Structure Information 3ff7 KLRG1 structure of nk cell receptor klrg1 bound to e-cadherin 1.8Å AUTH Y.LI,M.HOFMANN,Q.WANG,L.TENG,L.K.CHLEWICKI,AUTH 2 H.PIRCHER,R.A.MARIUZZATITL STRUCTURE OF NATURAL KILLER CELL RECEPTOR KLRG1TITL 2 BOUND TO E-CADHERIN REVEALS BASIS FORTITL 3 MHC-INDEPENDENT MISSING SELF RECOGNITION.REF IMMUNITY V. 31 35 2009REFN ISSN 1074-7613PMID 19604491DOI 10.1016/J.IMMUNI.2009.04.019 Variant Set Distributions Mapped Variants
General Structure Information 3n1q CDON crystal structure of dhhn bound to cdofn3 2.89Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Mapped Variants
General Structure Information 4n5x SLC25A24 crystal structure of n-terminal calmodulin-like calcium sensor of human mitochondrial atp-mg/pi carrier scamc1 2.1Å AUTH Q.YANG,S.BRUSCHWEILER,J.J.CHOUTITL A SELF-SEQUESTERED CALMODULIN-LIKE CA(2+) SENSOR OFTITL 2 MITOCHONDRIAL SCAMC CARRIER AND ITS IMPLICATION TOTITL 3 CA(2+)-DEPENDENT ATP-MG/PI TRANSPORT.REF STRUCTURE V. 22 209 2014REFN ISSN 0969-2126PMID 24332718DOI 10.1016/J.STR.2013.10.018 Variant Set Distributions Mapped Variants