Assessment of Structural Intolerance and Durability
General Structure Information 1v27 RIMS2 solution structure of the first c2 domain of rim2 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OF RIM2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jqz SMURF2 solution structure of the c2 domain of human smurf2 -1.0Å AUTH S.WIESNER,A.A.OGUNJIMI,H.-R.WANG,D.ROTIN,F.SICHERI,AUTH 2 J.L.WRANA,J.D.FORMAN-KAYTITL AUTOINHIBITION OF THE HECT-TYPE UBIQUITIN LIGASETITL 2 SMURF2 THROUGH ITS C2 DOMAINREF CELL(CAMBRIDGE,MASS.) V. 130 651 2007REFN ISSN 0092-8674PMID 17719543DOI 10.1016/J.CELL.2007.06.050 Variant Set Distributions Mapped Variants
General Structure Information 2enp SYT17 solution structure of the first c2 domain from human b/k protein -1.0Å AUTH H.ENDO,T.NAGASHIMA,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN FROMTITL 2 HUMAN B/K PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2nsq NEDD4L crystal structure of the c2 domain of the human e3 ubiquitin-protein ligase nedd4-like protein 1.85Å AUTH J.R.WALKER,G.V.AVVAKUMOV,S.XUE,C.BUTLER-COLE,AUTH 2 P.J.FINERTY JR.,J.WEIGELT,M.SUNDSTROM,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL THE C2 DOMAIN OF THE HUMAN E3 UBIQUITIN-PROTEIN LIGASETITL 2 NEDD4-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2nq3 ITCH crystal structure of the c2 domain of human itchy homolog e3 ubiquitin protein ligase 1.8Å AUTH J.R.WALKER,G.V.AVVAKUMOV,S.XUE,C.BUTLER-COLE,AUTH 2 P.J.FINERTY JR.,J.WEIGELT,M.SUNDSTROM,AUTH 3 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 4 S.DHE-PAGANONTITL THE C2 DOMAIN OF HUMAN ITCHY HOMOLOG E3 UBIQUITINTITL 2 PROTEIN LIGASEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2z0u WWC1 crystal structure of c2 domain of kibra protein 2.2Å AUTH K.MURAYAMA,M.KATO-MURAYAMA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF C2 DOMAIN OF KIBRA PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1wfm SYT13 the first c2 domain of human synaptotagmin xiii -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL THE FIRST C2 DOMAIN OF HUMAN SYNAPTOTAGMIN XIIIREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4mjj DOC2A crystal structure of the c2a domain of doc2a 2.0Å AUTH Q.Q.HUANGTITL CRYSTAL STRUCTURE OF THE C2A DOMAIN OF DOC2AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1yrk PRKCD the c2 domain of pkc is a new phospho-tyrosine binding domain 1.7Å AUTH C.H.BENES,N.WU,A.E.ELIA,T.DHARIA,L.C.CANTLEY,AUTH 2 S.P.SOLTOFFTITL THE C2 DOMAIN OF PKCDELTA IS A PHOSPHOTYROSINETITL 2 BINDING DOMAIN.REF CELL(CAMBRIDGE,MASS.) V. 121 271 2005REFN ISSN 0092-8674PMID 15851022DOI 10.1016/J.CELL.2005.02.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 4gnk PLCB3 crystal structure of galphaq in complex with full-length human plcbeta3 4.0Å AUTH A.M.LYON,S.DUTTA,C.A.BOGUTH,G.SKINIOTIS,J.J.TESMERTITL FULL-LENGTH G ALPHA (Q)-PHOSPHOLIPASE C-BETA 3 STRUCTURETITL 2 REVEALS INTERFACES OF THE C-TERMINAL COILED-COIL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 20 355 2013REFN ISSN 1545-9993PMID 23377541DOI 10.1038/NSMB.2497 Variant Set Distributions Mapped Variants