Assessment of Structural Intolerance and Durability
General Structure Information 2eho GINS2 crystal structure of human gins complex 3.0Å AUTH J.M.CHOI,H.S.LIM,J.J.KIM,O.K.SONG,Y.CHOTITL CRYSTAL STRUCTURE OF THE HUMAN GINS COMPLEXREF GENES DEV. V. 21 1316 2007REFN ISSN 0890-9369PMID 17545466DOI 10.1101/GAD.1548107 Variant Set Distributions Mapped Variants
General Structure Information 2lop TMEM14A backbone structure of human membrane protein tmem14a -1.0Å AUTH C.KLAMMT,I.MASLENNIKOV,M.BAYRHUBER,C.EICHMANN,N.VAJPAI,AUTH 2 E.J.CHIU,K.Y.BLAIN,L.ESQUIVIES,J.H.KWON,B.BALANA,U.PIEPER,AUTH 3 A.SALI,P.A.SLESINGER,W.KWIATKOWSKI,R.RIEK,S.CHOETITL FACILE BACKBONE STRUCTURE DETERMINATION OF HUMAN MEMBRANETITL 2 PROTEINS BY NMR SPECTROSCOPY.REF NAT.METHODS V. 9 834 2012REFN ISSN 1548-7091PMID 22609626DOI 10.1038/NMETH.2033 Variant Set Distributions Mapped Variants
General Structure Information 2p64 BTRC d domain of b-trcp 2.5Å AUTH X.TANG,S.ORLICKY,Z.LIN,A.WILLEMS,D.NECULAI,D.CECCARELLI,AUTH 2 F.MERCURIO,B.H.SHILTON,F.SICHERI,M.TYERSTITL SUPRAFACIAL ORIENTATION OF THE SCFCDC4 DIMER ACCOMMODATESTITL 2 MULTIPLE GEOMETRIES FOR SUBSTRATE UBIQUITINATION.REF CELL(CAMBRIDGE,MASS.) V. 129 1165 2007REFN ISSN 0092-8674PMID 17574027DOI 10.1016/J.CELL.2007.04.042 Variant Set Distributions Mapped Variants
General Structure Information 3dyt SNX9 crystal structure of snx9px-bar (230-595), c2221 2.08Å AUTH Q.WANG,H.Y.KAAN,R.N.HOODA,S.L.GOH,H.SONDERMANNTITL STRUCTURE AND PLASTICITY OF ENDOPHILIN AND SORTINGTITL 2 NEXIN 9.REF STRUCTURE V. 16 1574 2008REFN ISSN 0969-2126PMID 18940612DOI 10.1016/J.STR.2008.07.016 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3l4g FARSA crystal structure of homo sapiens cytoplasmic phenylalanyl-trna synthetase 3.3Å AUTH I.FINAROV,N.MOOR,N.KESSLER,L.KLIPCAN,M.G.SAFROTITL STRUCTURE OF HUMAN CYTOSOLIC PHENYLALANYL-TRNA SYNTHETASE:TITL 2 EVIDENCE FOR KINGDOM-SPECIFIC DESIGN OF THE ACTIVE SITESTITL 3 AND TRNA BINDING PATTERNS.REF STRUCTURE V. 18 343 2010REFN ISSN 0969-2126PMID 20223217DOI 10.1016/J.STR.2010.01.002 Variant Set Distributions Mapped Variants
General Structure Information 2lom HIGD1A backbone structure of human membrane protein higd1a -1.0Å AUTH C.KLAMMT,I.MASLENNIKOV,M.BAYRHUBER,C.EICHMANN,N.VAJPAI,AUTH 2 E.J.CHIU,K.Y.BLAIN,L.ESQUIVIES,J.H.KWON,B.BALANA,U.PIEPER,AUTH 3 A.SALI,P.A.SLESINGER,W.KWIATKOWSKI,R.RIEK,S.CHOETITL FACILE BACKBONE STRUCTURE DETERMINATION OF HUMAN MEMBRANETITL 2 PROTEINS BY NMR SPECTROSCOPY.REF NAT.METHODS V. 9 834 2012REFN ISSN 1548-7091PMID 22609626DOI 10.1038/NMETH.2033 Variant Set Distributions Mapped Variants
General Structure Information 2h80 STARD13 nmr structures of sam domain of deleted in liver cancer 2 (dlc2) -1.0Å AUTH H.LI,K.L.FUNG,D.Y.JIN,S.S.CHUNG,Y.P.CHING,I.O.NG,AUTH 2 K.H.SZE,B.C.KO,H.SUNTITL SOLUTION STRUCTURES, DYNAMICS, AND LIPID-BINDINGTITL 2 OF THE STERILE ALPHA-MOTIF DOMAIN OF THE DELETEDTITL 3 IN LIVER CANCER 2REF PROTEINS V. 67 1154 2007REFN ISSN 0887-3585PMID 17380510DOI 10.1002/PROT.21361 Variant Set Distributions Mapped Variants
General Structure Information 2los TMEM14C backbone structure of human membrane protein tmem14c -1.0Å AUTH C.KLAMMT,I.MASLENNIKOV,M.BAYRHUBER,C.EICHMANN,N.VAJPAI,AUTH 2 E.J.CHIU,K.Y.BLAIN,L.ESQUIVIES,J.H.KWON,B.BALANA,U.PIEPER,AUTH 3 A.SALI,P.A.SLESINGER,W.KWIATKOWSKI,R.RIEK,S.CHOETITL FACILE BACKBONE STRUCTURE DETERMINATION OF HUMAN MEMBRANETITL 2 PROTEINS BY NMR SPECTROSCOPY.REF NAT.METHODS V. 9 834 2012REFN ISSN 1548-7091PMID 22609626DOI 10.1038/NMETH.2033 Variant Set Distributions Mapped Variants
General Structure Information 2d9d BAG5 solution structure of the bag domain (275-350) of bag-family molecular chaperone regulator-5 -1.0Å AUTH A.ARAKAWA,N.HANDA,N.OHSAWA,M.SHIDA,T.KIGAWA,AUTH 2 F.HAYASHI,M.SHIROUZU,S.YOKOYAMATITL THE C-TERMINAL BAG DOMAIN OF BAG5 INDUCESTITL 2 CONFORMATIONAL CHANGES OF THE HSP70TITL 3 NUCLEOTIDE-BINDING DOMAIN FOR ADP-ATP EXCHANGEREF STRUCTURE V. 18 309 2010REFN ISSN 0969-2126PMID 20223214DOI 10.1016/J.STR.2010.01.004 Variant Set Distributions Mapped Variants
General Structure Information 1nwm GGA1 gat domain of human gga1 2.4Å AUTH S.SUER,S.MISRA,L.F.SAIDI,J.H.HURLEYTITL STRUCTURE OF THE GAT DOMAIN OF HUMAN GGA1: ATITL 2 SYNTAXIN AMINO-TERMINAL DOMAIN FOLD IN ANTITL 3 ENDOSOMAL TRAFFICKING ADAPTOR.REF PROC.NATL.ACAD.SCI.USA V. 100 4451 2003REFN ISSN 0027-8424PMID 12668765DOI 10.1073/PNAS.0831133100 Variant Set Distributions Mapped Variants