Assessment of Structural Intolerance and Durability
General Structure Information 3u9j FBXL5 crystal structure of oxidized human fbxl5 hemerythrin like domain 1.6Å AUTH C.SHU,M.W.SUNG,M.D.STEWART,T.I.IGUMENOVA,X.TAN,P.LITITL THE STRUCTURAL BASIS OF IRON SENSING BY THE HUMAN F-BOXTITL 2 PROTEIN FBXL5.REF CHEMBIOCHEM V. 13 788 2012REFN ISSN 1439-4227PMID 22492618DOI 10.1002/CBIC.201200043 Variant Set Distributions Mapped Variants
General Structure Information 3jtc PROCR importance of mg2+ in the ca2+-dependent folding of the gamma- carboxyglutamic acid domains of vitamin k-dependent clotting and anticlotting proteins 1.6Å AUTH K.VADIVEL,S.AGAH,A.S.MESSER,D.CASCIO,M.S.BAJAJ,AUTH 2 S.KRISHNASWAMY,C.T.ESMON,K.PADMANABHAN,S.P.BAJAJTITL STRUCTURAL AND FUNCTIONAL STUDIES OF GAMMA-CARBOXYGLUTAMICTITL 2 ACID DOMAINS OF FACTOR VIIA AND ACTIVATED PROTEIN C: ROLE OFTITL 3 MAGNESIUM AT PHYSIOLOGICAL CALCIUM.REF J.MOL.BIOL. V. […]
General Structure Information 2dmk MID2 the solution structure of the fn3 domain of human midline 2 protein -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE FN3 DOMAIN OF HUMANTITL 2 MIDLINE 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3toj ASH2L structure of the spry domain of human ash2l 2.07Å AUTH Y.CHEN,F.CAO,B.WAN,Y.DOU,M.LEITITL STRUCTURE OF THE SPRY DOMAIN OF HUMAN ASH2L AND ITSTITL 2 INTERACTIONS WITH RBBP5 AND DPY30.REF CELL RES. V. 22 598 2012REFN ISSN 1001-0602PMID 22231628DOI 10.1038/CR.2012.9 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3ose MARK1 structure of the kinase associated domain 1 (ka1) from mark1 kinase 1.7Å AUTH K.MORAVCEVIC,J.M.MENDROLA,K.R.SCHMITZ,Y.H.WANG,D.SLOCHOWER,AUTH 2 P.A.JANMEY,M.A.LEMMONTITL KINASE ASSOCIATED-1 DOMAINS DRIVE MARK/PAR1 KINASES TOTITL 2 MEMBRANE TARGETS BY BINDING ACIDIC PHOSPHOLIPIDS.REF CELL(CAMBRIDGE,MASS.) V. 143 966 2010REFN ISSN 0092-8674PMID 21145462DOI 10.1016/J.CELL.2010.11.028 Variant Set Distributions Mapped Variants
General Structure Information 2b1u CALML5 solution structure of calmodulin-like skin protein c terminal domain -1.0Å AUTH E.BABINI,I.BERTINI,F.CAPOZZI,E.CHIRIVINO,C.LUCHINATTITL A STRUCTURAL AND DYNAMIC CHARACTERIZATION OF THETITL 2 EF-HAND PROTEIN CLSP.REF STRUCTURE V. 14 1029 2006REFN ISSN 0969-2126PMID 16765896DOI 10.1016/J.STR.2006.04.004 Variant Set Distributions Mapped Variants
General Structure Information 1×67 DBNL solution structure of the cofilin homology domain of hip-55 (drebrin-like protein) -1.0Å AUTH A.K.GORONCY,S.KOSHIBA,N.TOCHIO,T.TOMIZAWA,M.SATO,AUTH 2 M.INOUE,S.WATANABE,Y.HAYASHIZAKI,A.TANAKA,T.KIGAWA,AUTH 3 S.YOKOYAMATITL NMR SOLUTION STRUCTURES OF ACTIN DEPOLYMERIZINGTITL 2 FACTOR HOMOLOGY DOMAINS.REF PROTEIN SCI. V. 18 2384 2009REFN ISSN 0961-8368PMID 19768801DOI 10.1002/PRO.248 Variant Set Distributions Mapped Variants
General Structure Information 4bld SUFU crystal structure of a human suppressor of fused (sufu)- gli3p complex 2.8Å AUTH A.L.CHERRY,C.FINTA,M.KARLSTROM,Q.JIN,T.SCHWEND,AUTH 2 J.ASTORGA-WELLS,R.A.ZUBAREV,M.DEL CAMPO,A.R.CRISWELL,AUTH 3 D.DE SANCTIS,L.JOVINE,R.TOFTGARDTITL STRUCTURAL BASIS OF SUFU-GLI INTERACTION IN HEDGEHOGTITL 2 SIGNALLING REGULATIONREF ACTA CRYSTALLOGR.,SECT.D V. 69 2579 2013REFN ISSN 0907-4449PMID 24311597DOI 10.1107/S0907444913028473 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1w0b AHSP solution structure of the human alpha-hemoglobin stabilizing protein (ahsp) p30a mutant -1.0Å AUTH C.M.SANTIVERI,J.M.PEREZ-CANADILLAS,M.K.VADIVELU,AUTH 2 M.D.ALLEN,T.J.RUTHERFORD,N.A.WATKINS,M.BYCROFTTITL NMR STRUCTURE OF THE ALPHA-HEMOGLOBIN CHAPERONETITL 2 AHSP: INSIGHTS INTO CONFORMATIONAL HETEROGENEITYTITL 3 AND BINDINGREF J.BIOL.CHEM. V. 279 34963 2004REFN ISSN 0021-9258PMID 15178680DOI 10.1074/JBC.M405016200 Variant Set Distributions Mapped Variants
General Structure Information 2g4c POLG2 crystal structure of human dna polymerase gamma accessory subunit 3.15Å AUTH L.FAN,S.KIM,C.L.FARR,K.T.SCHAEFER,K.M.RANDOLPH,AUTH 2 J.A.TAINER,L.S.KAGUNITITL A NOVEL PROCESSIVE MECHANISM FOR DNA SYNTHESISTITL 2 REVEALED BY STRUCTURE, MODELING AND MUTAGENESIS OFTITL 3 THE ACCESSORY SUBUNIT OF HUMAN MITOCHONDRIAL DNATITL 4 POLYMERASEREF J.MOL.BIOL. V. 358 1229 2006REFN ISSN 0022-2836PMID 16574152DOI 10.1016/J.JMB.2006.02.073 Variant Set […]