General Structure Information
| PDB ID | 4bld |
| HGNC Gene Label(s) | SUFU |
| Structure Name | crystal structure of a human suppressor of fused (sufu)- gli3p complex |
| Resolution | 2.8Å |
| Reference | AUTH A.L.CHERRY,C.FINTA,M.KARLSTROM,Q.JIN,T.SCHWEND,AUTH 2 J.ASTORGA-WELLS,R.A.ZUBAREV,M.DEL CAMPO,A.R.CRISWELL,AUTH 3 D.DE SANCTIS,L.JOVINE,R.TOFTGARDTITL STRUCTURAL BASIS OF SUFU-GLI INTERACTION IN HEDGEHOGTITL 2 SIGNALLING REGULATIONREF ACTA CRYSTALLOGR.,SECT.D V. 69 2579 2013REFN ISSN 0907-4449PMID 24311597DOI 10.1107/S0907444913028473 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 343 |
| Number Of SNVs | 63 |
| Number Of Permutations | 11552 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.044 |
| p-value | 0.609 |
COSMIC
| Number Of Residues | 343 |
| Number Of SNVs | 5 |
| Number Of Permutations | 330 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.2 |
| p-value | 0.99 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 63 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.26 |
| p-value | 0.46 |