Assessment of Structural Intolerance and Durability
General Structure Information 3rqf PDCD10 cerebral cavernous malformation 3 (ccm3) in complex with paxillin ld2 2.7Å AUTH X.LI,W.JI,R.ZHANG,E.FOLTA-STOGNIEW,W.MIN,T.J.BOGGONTITL MOLECULAR RECOGNITION OF LEUCINE-ASPARTATE REPEAT (LD)TITL 2 MOTIFS BY THE FOCAL ADHESION TARGETING HOMOLOGY DOMAIN OFTITL 3 CEREBRAL CAVERNOUS MALFORMATION 3 (CCM3).REF J.BIOL.CHEM. V. 286 26138 2011REFN ISSN 0021-9258PMID 21632544DOI 10.1074/JBC.M110.211250 Variant Set Distributions Mapped Variants
General Structure Information 4fqn CCM2 crystal structure of the ccm2 c-terminal harmonin homology domain (hhd) 1.9Å AUTH O.S.FISHER,R.ZHANG,X.LI,J.W.MURPHY,B.DEMELER,T.J.BOGGONTITL STRUCTURAL STUDIES OF CEREBRAL CAVERNOUS MALFORMATIONS 2TITL 2 (CCM2) REVEAL A FOLDED HELICAL DOMAIN AT ITS C-TERMINUS.REF FEBS LETT. V. 587 272 2013REFN ISSN 0014-5793PMID 23266514DOI 10.1016/J.FEBSLET.2012.12.011 Variant Set Distributions Mapped Variants
General Structure Information 3op5 VRK1 human vaccinia-related kinase 1 2.4Å AUTH C.K.ALLERSTON,S.UTTARKAR,P.SAVITSKY,J.M.ELKINS,AUTH 2 P.FILIPPAKOPOULOS,T.KROJER,P.RELLOS,O.FEDOROV,J.ESWARAN,AUTH 3 B.BRENNER,T.KEATES,S.DAS,O.KING,R.CHALK,G.BERRIDGE,AUTH 4 F.VON DELFT,O.GILEADI,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,AUTH 5 C.BOUNTRA,S.KNAPPTITL HUMAN VACCINIA-RELATED KINASE 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3vtw MAP1LC3B crystal structure of t7-tagged optineurin lir-fused human lc3b_2-119 2.52Å AUTH V.V.ROGOV,H.SUZUKI,E.FISKIN,P.WILD,A.KNISS,A.ROZENKNOP,AUTH 2 R.KATO,M.KAWASAKI,D.G.MCEWAN,F.LOHR,P.GUNTERT,I.DIKIC,AUTH 3 S.WAKATSUKI,V.DOTSCHTITL STRUCTURAL BASIS FOR PHOSPHORYLATION-TRIGGERED AUTOPHAGICTITL 2 CLEARANCE OF SALMONELLAREF BIOCHEM.J. V. 454 459 2013REFN ISSN 0264-6021PMID 23805866DOI 10.1042/BJ20121907 Variant Set Distributions Mapped Variants
General Structure Information 1×52 PELO solution structures of the c-terminal domain of the human pelota homolog (cgi-17) -1.0Å AUTH N.NAMEKI,M.SATO,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C-TERMINAL DOMAIN OFTITL 2 THE HUMAN PELOTA HOMOLOG (CGI-17)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3tvl THTPA complex between the human thiamine triphosphatase and triphosphate 2.3Å AUTH D.DELVAUX,F.KERFF,M.R.MURTY,B.LAKAYE,J.CZERNIECKI,G.KOHN,AUTH 2 P.WINS,R.HERMAN,V.GABELICA,F.HEUZE,X.TORDOIR,R.MAREE,AUTH 3 A.MATAGNE,P.CHARLIER,E.DE PAUW,L.BETTENDORFFTITL STRUCTURAL DETERMINANTS OF SPECIFICITY AND CATALYTICTITL 2 MECHANISM IN MAMMALIAN 25-KDA THIAMINE TRIPHOSPHATASE.REF BIOCHIM.BIOPHYS.ACTA V.1830 4513 2013REFN ISSN 0006-3002PMID 23707715DOI 10.1016/J.BBAGEN.2013.05.014 Variant Set Distributions Mapped Variants
General Structure Information 2kpk MAGI1 magi-1 pdz1 -1.0Å AUTH S.CHARBONNIER,Y.NOMINE,J.RAMIREZ,K.LUCK,A.CHAPELLE,AUTH 2 R.H.STOTE,G.TRAVE,B.KIEFFER,R.A.ATKINSONTITL THE STRUCTURAL AND DYNAMIC RESPONSE OF MAGI-1 PDZ1 WITHTITL 2 NON-CANONICAL DOMAIN BOUNDARIES TO BINDING OF HUMANTITL 3 PAPILLOMAVIRUS (HPV) E6REF J.MOL.BIOL. 2011REFN ESSN 1089-8638PMID 21238461DOI 10.1016/J.JMB.2011.01.015 Variant Set Distributions Mapped Variants
General Structure Information 4jvh QKI structure of the star domain of quaking protein in complex with rna 3.5Å AUTH M.TEPLOVA,M.HAFNER,D.TEPLOV,K.ESSIG,T.TUSCHL,D.J.PATELTITL STRUCTURE-FUNCTION STUDIES OF STAR FAMILY QUAKING PROTEINSTITL 2 BOUND TO THEIR IN VIVO RNA TARGET SITES.REF GENES DEV. V. 27 928 2013REFN ISSN 0890-9369PMID 23630077DOI 10.1101/GAD.216531.113 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2mc3 MUS81 nmr solution structure of the winged-helix domain from mus81 structure-specific endonuclease -1.0Å AUTH A.J.FADDEN,S.SCHALBETTER,M.BOWLES,R.HARRIS,J.LALLY,A.M.CARR,AUTH 2 N.Q.MCDONALDTITL A WINGED HELIX DOMAIN IN HUMAN MUS81 BINDS DNA AND MODULATESTITL 2 THE ENDONUCLEASE ACTIVITY OF MUS81 COMPLEXES.REF NUCLEIC ACIDS RES. V. 41 9741 2013REFN ISSN 0305-1048PMID 23982516DOI 10.1093/NAR/GKT760 Variant Set Distributions Mapped Variants
General Structure Information 2e30 CHP1 solution structure of the cytoplasmic region of na+/h+ exchanger 1 complexed with essential cofactor calcineurin b homologous protein 1 -1.0Å AUTH M.MISHIMA,S.WAKABAYASHI,C.KOJIMATITL SOLUTION STRUCTURE OF THE CYTOPLASMIC REGION OFTITL 2 NA+/H+ EXCHANGER 1 COMPLEXED WITH ESSENTIALTITL 3 COFACTOR CALCINEURIN B HOMOLOGOUS PROTEIN 1REF J.BIOL.CHEM. V. 282 2741 2007REFN ISSN 0021-9258PMID […]