Assessment of Structural Intolerance and Durability
General Structure Information 3kqg CD207 trimeric structure of langerin 2.3Å AUTH H.FEINBERG,A.S.POWLESLAND,M.E.TAYLOR,W.I.WEISTITL TRIMERIC STRUCTURE OF LANGERIN.REF J.BIOL.CHEM. V. 285 13285 2010REFN ISSN 0021-9258PMID 20181944DOI 10.1074/JBC.M109.086058 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4irq B4GALT7 crystal structure of catalytic domain of human beta1, 4galactosyltransferase 7 in closed conformation in complex with manganese and udp 2.3Å AUTH Y.TSUTSUI,B.RAMAKRISHNAN,P.K.QASBATITL CRYSTAL STRUCTURES OF BETA-1,4-GALACTOSYLTRANSFERASE 7TITL 2 ENZYME REVEAL CONFORMATIONAL CHANGES AND SUBSTRATE BINDING.REF J.BIOL.CHEM. V. 288 31963 2013REFN ISSN 0021-9258PMID 24052259DOI 10.1074/JBC.M113.509984 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 2cq1 PTBP2 solution structure of rna binding domain in ptb-like protein l -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 PTB-LIKE PROTEIN LREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2daw RWDD2A solution structure of the rwd domain of human rwd omain containing protein 2 -1.0Å AUTH M.YONEYAMA,T.KIGAWA,M.SATO,N.TOCHIO,S.KOSHIBA,AUTH 2 M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RWD DOMAIN OF HUMAN RWDTITL 2 OMAIN CONTAINING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dzm FAF1 solution structure of the ubiquitin-like domain in human fas-associated factor 1 (hfaf1) -1.0Å AUTH C.ZHAO,M.SATO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE UBIQUITIN-LIKE DOMAIN INTITL 2 HUMAN FAS-ASSOCIATED FACTOR 1 (HFAF1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ec1 NUP50 solution structure of the ranbd1 domain from human nucleoporin 50 kda -1.0Å AUTH H.P.ZHANG,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RANBD1 DOMAIN FROM HUMANTITL 2 NUCLEOPORIN 50 KDAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1×51 MUTYH solution structure of the nudix domain from human a/g- specific adenine dna glycosylase alpha-3 splice isoform -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE NUDIX DOMAIN FROM HUMANTITL 2 A/G-SPECIFIC ADENINE DNA GLYCOSYLASE ALPHA-3TITL 3 SPLICE ISOFORMREF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ej8 APPL1 crystal structure of appl1 ptb domain at 1.8a 1.84Å AUTH H.TANABE,T.HOSAKA,K.MURAYAMA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF APPL1 PTB DOMAIN AT 1.8AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ebw REV1 solution structure of the brct domain from human dna repair protein rev1 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE BRCT DOMAIN FROM HUMANTITL 2 DNA REPAIR PROTEIN REV1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ee3 COL20A1 solution structures of the fn3 domain of human collagen alpha-1(xx) chain -1.0Å AUTH M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE FN3 DOMAIN OF HUMANTITL 2 COLLAGEN ALPHA-1(XX) CHAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants