3KQG.B | CD207

General Structure Information

PDB ID 3kqg
HGNC Gene Label(s) CD207
Structure Name trimeric structure of langerin
Resolution 2.3Å
Reference AUTH H.FEINBERG,A.S.POWLESLAND,M.E.TAYLOR,W.I.WEISTITL TRIMERIC STRUCTURE OF LANGERIN.REF J.BIOL.CHEM. V. 285 13285 2010REFN ISSN 0021-9258PMID 20181944DOI 10.1074/JBC.M109.086058

Variant Set Distributions

ExAC Variants

Number Of Residues 157
Number Of SNVs 42
Number Of Permutations 44385
Optimal Distance Threshold 7.0
K Statistic 0.049
p-value 0.91
COSMIC

Number Of Residues 157
Number Of SNVs 8
Number Of Permutations 10076
Optimal Distance Threshold 13.0
K Statistic 0.036
p-value 0.129

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 42
Number Of COSMIC SNVs 5
Optimal Distance Threshold 28.0
K Statistic -0.236
p-value 0.56

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants