General Structure Information 2i38 SRSF3 solution structure of the rrm of srp20 -1.0Å AUTH Y.HARGOUS,G.M.HAUTBERGUE,A.M.TINTARU,L.SKRISOVSKA,AUTH 2 A.P.GOLOVANOV,J.STEVENIN,L.Y.LIAN,S.A.WILSON,AUTH 3 F.H.ALLAINTITL MOLECULAR BASIS OF RNA RECOGNITION AND TAP BINDINGTITL 2 BY THE SR PROTEINS SRP20 AND 9G8.REF EMBO J. V. 25 5126 2006REFN ISSN 0261-4189PMID 17036044DOI 10.1038/SJ.EMBOJ.7601385 Variant Set Distributions Mapped Variants
General Structure Information 1dt4 NOVA1 crystal structure of nova-1 kh3 k-homology rna-binding domain 2.6Å AUTH H.A.LEWIS,H.CHEN,C.EDO,R.J.BUCKANOVICH,Y.Y.YANG,AUTH 2 K.MUSUNURU,R.ZHONG,R.B.DARNELL,S.K.BURLEYTITL CRYSTAL STRUCTURES OF NOVA-1 AND NOVA-2 K-HOMOLOGYTITL 2 RNA-BINDING DOMAINS.REF STRUCTURE FOLD.DES. V. 7 191 1999REFN ISSN 0969-2126PMID 10368286DOI 10.1016/S0969-2126(99)80025-2 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1srq RAP1GAP crystal structure of the rap1gap catalytic domain 2.9Å AUTH O.DAUMKE,M.WEYAND,P.P.CHAKRABARTI,I.R.VETTER,A.WITTINGHOFERTITL THE GTPASE ACTIVATING PROTEIN RAP1GAP USES A CATALYTICTITL 2 ASPARAGINEREF NATURE V. 429 197 2004REFN ISSN 0028-0836PMID 15141215DOI 10.1038/NATURE02505 Variant Set Distributions Mapped Variants
General Structure Information 1ihi AKR1C2 crystal structure of human type iii 3-alpha-hydroxysteroid dehydrogenase/bile acid binding protein (akr1c2) complexed with nadp+ and ursodeoxycholate 3.0Å AUTH Y.JIN,S.E.STAYROOK,R.H.ALBERT,N.T.PALACKAL,AUTH 2 T.M.PENNING,M.LEWISTITL CRYSTAL STRUCTURE OF HUMAN TYPE IIITITL 2 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/BILE ACIDTITL 3 BINDING PROTEIN COMPLEXED WITH NADP(+) ANDTITL 4 URSODEOXYCHOLATE.REF BIOCHEMISTRY V. 40 10161 2001REFN ISSN 0006-2960PMID 11513593DOI 10.1021/BI010919A […]
General Structure Information 3eto NOTCH1 2 angstrom xray structure of the notch1 negative regulatory region (nrr) 2.0Å AUTH W.R.GORDON,M.ROY,D.VARDAR-ULU,M.GARFINKEL,M.R.MANSOUR,AUTH 2 J.C.ASTER,S.C.BLACKLOWTITL STRUCTURE OF THE NOTCH1-NEGATIVE REGULATORY REGION:TITL 2 IMPLICATIONS FOR NORMAL ACTIVATION AND PATHOGENIC SIGNALINGTITL 3 IN T-ALL.REF BLOOD V. 113 4381 2009REFN ISSN 0006-4971PMID 19075186DOI 10.1182/BLOOD-2008-08-174748 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 1f05 TALDO1 crystal structure of human transaldolase 2.45Å AUTH S.THORELL,P.GERGELY JR.,K.BANKI,A.PERL,G.SCHNEIDERTITL THE THREE-DIMENSIONAL STRUCTURE OF HUMANTITL 2 TRANSALDOLASE.REF FEBS LETT. V. 475 205 2000REFN ISSN 0014-5793PMID 10869557DOI 10.1016/S0014-5793(00)01658-6 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2atx RHOQ crystal structure of the tc10 gppnhp complex 2.65Å AUTH L.HEMSATH,R.DVORSKY,D.FIEGEN,M.F.CARLIER,M.R.AHMADIANTITL AN ELECTROSTATIC STEERING MECHANISM OF CDC42 RECOGNITION BYTITL 2 WISKOTT-ALDRICH SYNDROME PROTEINSREF MOL.CELL V. 20 313 2005REFN ISSN 1097-2765PMID 16246732DOI 10.1016/J.MOLCEL.2005.08.036 Variant Set Distributions Mapped Variants
General Structure Information 4jnk LDHA lactate dehydrogenase a in complex with inhibitor compound 22 1.9Å AUTH P.S.DRAGOVICH,B.P.FAUBER,L.B.CORSON,C.Z.DING,C.EIGENBROT,AUTH 2 H.GE,A.M.GIANNETTI,T.HUNSAKER,S.LABADIE,Y.LIU,S.MALEK,B.PAN,AUTH 3 D.PETERSON,K.PITTS,H.E.PURKEY,S.SIDERIS,M.ULTSCH,AUTH 4 E.VANDERPORTEN,B.WEI,Q.XU,I.YEN,Q.YUE,H.ZHANG,X.ZHANGTITL IDENTIFICATION OF SUBSTITUTEDTITL 2 2-THIO-6-OXO-1,6-DIHYDROPYRIMIDINES AS INHIBITORS OF HUMANTITL 3 LACTATE DEHYDROGENASE.REF BIOORG.MED.CHEM.LETT. V. 23 3186 2013REFN ISSN 0960-894XPMID 23628333DOI 10.1016/J.BMCL.2013.04.001 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]