Assessment of Structural Intolerance and Durability
General Structure Information 3l15 TEAD2 human tead2 transcriptional factor 2.0Å AUTH W.TIAN,J.YU,D.R.TOMCHICK,D.PAN,X.LUOTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE YAP-BINDINGTITL 2 DOMAIN OF HUMAN TEAD2.REF PROC.NATL.ACAD.SCI.USA V. 107 7293 2010REFN ISSN 0027-8424PMID 20368466DOI 10.1073/PNAS.1000293107 Variant Set Distributions Mapped Variants
General Structure Information 3g73 FOXM1 structure of the foxm1 dna binding 2.21Å AUTH D.R.LITTLER,M.ALVAREZ-FERNANDEZ,A.STEIN,R.G.HIBBERT,AUTH 2 T.HEIDEBRECHT,P.ALOY,R.H.MEDEMA,A.PERRAKISTITL STRUCTURE OF THE FOXM1 DNA-RECOGNITION DOMAIN BOUND TO ATITL 2 PROMOTER SEQUENCEREF NUCLEIC ACIDS RES. 2010REFN ESSN 1362-4962PMID 20360045DOI 10.1093/NAR/GKQ194 Variant Set Distributions Mapped Variants
General Structure Information 2qpw PRDM2 methyltransferase domain of human pr domain-containing protein 2 1.79Å AUTH H.WU,J.MIN,V.V.LUNIN,T.ANTOSHENKO,L.DOMBROVSKI,AUTH 2 H.ZENG,A.ALLALI-HASSANI,V.CAMPAGNA-SLATER,M.VEDADI,AUTH 3 C.H.ARROWSMITH,A.N.PLOTNIKOV,M.SCHAPIRATITL STRUCTURAL BIOLOGY OF HUMAN H3K9 METHYLTRANSFERASESREF PLOS ONE V. 5 E8570 2010REFN ESSN 1932-6203PMID 20084102DOI 10.1371/JOURNAL.PONE.0008570 Variant Set Distributions Mapped Variants
General Structure Information 1avo PSME1 proteasome activator reg(alpha) 2.8Å AUTH J.R.KNOWLTON,S.C.JOHNSTON,F.G.WHITBY,C.REALINI,AUTH 2 Z.ZHANG,M.RECHSTEINER,C.P.HILLTITL STRUCTURE OF THE PROTEASOME ACTIVATOR REGALPHATITL 2 (PA28ALPHA).REF NATURE V. 390 639 1997REFN ISSN 0028-0836PMID 9403698DOI 10.1038/37670 Variant Set Distributions Mapped Variants
General Structure Information 3llm DHX9 crystal structure analysis of a rna helicase 2.8Å AUTH P.SCHUTZ,E.WAHLBERG,T.KARLBERG,M.HAMMARSTROM,R.COLLINS,AUTH 2 A.FLORES,H.SCHULERTITL CRYSTAL STRUCTURE OF HUMAN RNA HELICASE A (DHX9): STRUCTURALTITL 2 BASIS FOR UNSELECTIVE NUCLEOTIDE BASE BINDING IN A DEAD-BOXTITL 3 VARIANT PROTEIN.REF J.MOL.BIOL. V. 400 768 2010REFN ISSN 0022-2836PMID 20510246DOI 10.1016/J.JMB.2010.05.046 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3gut RELA crystal structure of a higher-order complex of p50:rela bound to the hiv-1 ltr 3.59Å AUTH J.C.STROUD,A.OLTMAN,A.HAN,D.L.BATES,L.CHENTITL STRUCTURAL BASIS OF HIV-1 ACTIVATION BYTITL 2 NF-KAPPAB–A HIGHER-ORDER COMPLEX OF P50:RELA BOUNDTITL 3 TO THE HIV-1 LTR.REF J.MOL.BIOL. V. 393 98 2009REFN ISSN 0022-2836PMID 19683540DOI 10.1016/J.JMB.2009.08.023 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1gzh TP53BP1 crystal structure of the brct domains of human 53bp1 bound to the p53 tumor supressor 2.6Å AUTH D.J.DERBYSHIRE,B.P.BASU,L.SERPELL,W.JOO,T.DATE,AUTH 2 K.IWABUCHI,A.J.DOHERTYTITL CRYSTAL STRUCTURE OF HUMAN 53BP1 BRCT DOMAINSTITL 2 BOUND TO P53 TUMOUR SUPPRESSORREF EMBO J. V. 21 3863 2002REFN ISSN 0261-4189PMID 12110597DOI 10.1093/EMBOJ/CDF383 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2rs9 BRPF1 solution structure of the bromodomain of human brpf1 in complex with histone h4k5ac peptide -1.0Å AUTH X.QIN,F.HAYASHI,S.YOKOYAMATITL SITE-SPECIFIC HISTONE RECOGNITION BY THE BROMODOMAIN OFTITL 2 BRPF1 AND THE ROLE IN MOZ/MORF HISTONE ACETYLTRANSFERASETITL 3 COMPLEXESREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3h7h SUPT4H1 crystal structure of the human transcription elongation factor dsif, hspt4/hspt5 (176-273) 1.55Å AUTH S.WENZEL,B.M.MARTINS,P.ROSCH,B.M.WOHRLTITL CRYSTAL STRUCTURE OF THE HUMAN TRANSCRIPTION ELONGATIONTITL 2 FACTOR DSIF HSPT4 SUBUNIT IN COMPLEX WITH THE HSPT5TITL 3 DIMERIZATION INTERFACEREF BIOCHEM.J. V. 425 373 2010REFN ISSN 0264-6021PMID 19860741DOI 10.1042/BJ20091422 Variant Set Distributions Mapped Variants
General Structure Information 3g73 FOXM1 structure of the foxm1 dna binding 2.21Å AUTH D.R.LITTLER,M.ALVAREZ-FERNANDEZ,A.STEIN,R.G.HIBBERT,AUTH 2 T.HEIDEBRECHT,P.ALOY,R.H.MEDEMA,A.PERRAKISTITL STRUCTURE OF THE FOXM1 DNA-RECOGNITION DOMAIN BOUND TO ATITL 2 PROMOTER SEQUENCEREF NUCLEIC ACIDS RES. 2010REFN ESSN 1362-4962PMID 20360045DOI 10.1093/NAR/GKQ194 Variant Set Distributions Mapped Variants