Assessment of Structural Intolerance and Durability
General Structure Information 1avf PGC activation intermediate 2 of human gastricsin from human stomach 2.36Å AUTH A.R.KHAN,M.M.CHERNEY,N.I.TARASOVA,M.N.JAMESTITL STRUCTURAL CHARACTERIZATION OF ACTIVATIONTITL 2 INTERMEDIATE 2 ON THE PATHWAY TO HUMANTITL 3 GASTRICSIN.REF NAT.STRUCT.BIOL. V. 4 1010 1997REFN ISSN 1072-8368PMID 9406551DOI 10.1038/NSB1297-1010 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3ije ITGB3 crystal structure of the complete integrin alhavbeta3 ectodomain plus an alpha/beta transmembrane fragment 2.9Å AUTH J.P.XIONG,B.MAHALINGHAM,J.L.ALONSO,L.A.BORRELLI,X.RUI,AUTH 2 S.ANAND,B.T.HYMAN,T.RYSIOK,D.MULLER-POMPALLA,S.L.GOODMAN,AUTH 3 M.A.ARNAOUTTITL CRYSTAL STRUCTURE OF THE COMPLETE INTEGRIN ALPHAVBETA3TITL 2 ECTODOMAIN PLUS AN ALPHA/BETA TRANSMEMBRANE FRAGMENT.REF J.CELL BIOL. V. 186 589 2009REFN ISSN 0021-9525PMID 19704023DOI 10.1083/JCB.200905085 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 4c59 GAK structure of gak kinase in complex with nanobody (nbgak_4) 2.8Å AUTH A.CHAIKUAD,T.KEATES,C.VINCKE,M.KAUFHOLZ,M.ZENN,B.ZIMMERMANN,AUTH 2 C.GUTIERREZ,R.ZHANG,C.HATZOS-SKINTGES,A.JOACHIMIAK,AUTH 3 S.MUYLDERMANS,F.W.HERBERG,S.KNAPP,S.MULLERTITL STRUCTURE OF CYCLIN G-ASSOCIATED KINASE (GAK) TRAPPED INTITL 2 DIFFERENT CONFORMATIONS USING NANOBODIES.REF BIOCHEM.J. V. 459 59 2014REFN ISSN 0264-6021PMID 24438162DOI 10.1042/BJ20131399 Variant Set Distributions Mapped Variants