General Structure Information
| PDB ID | 1avf |
| HGNC Gene Label(s) | PGC |
| Structure Name | activation intermediate 2 of human gastricsin from human stomach |
| Resolution | 2.36Å |
| Reference | AUTH A.R.KHAN,M.M.CHERNEY,N.I.TARASOVA,M.N.JAMESTITL STRUCTURAL CHARACTERIZATION OF ACTIVATIONTITL 2 INTERMEDIATE 2 ON THE PATHWAY TO HUMANTITL 3 GASTRICSIN.REF NAT.STRUCT.BIOL. V. 4 1010 1997REFN ISSN 1072-8368PMID 9406551DOI 10.1038/NSB1297-1010 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 322 |
| Number Of SNVs | 95 |
| Number Of Permutations | 13916 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.142 |
| p-value | 0.045 |
COSMIC
| Number Of Residues | 322 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1094 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.4 |
| p-value | 0.479 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 95 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.135 |
| p-value | 0.815 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
