General Structure Information 4hzs TNK2 crystal structure of ack1 kinase domain with c-terminal sh3 domain 3.23Å AUTH K.S.GAJIWALA,K.MAEGLEY,R.FERRE,Y.A.HE,X.YUTITL ACK1: ACTIVATION AND REGULATION BY ALLOSTERY.REF PLOS ONE V. 8 53994 2013REFN ESSN 1932-6203PMID 23342057DOI 10.1371/JOURNAL.PONE.0053994 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4hmy AP1B1 structural basis for recruitment and activation of the ap-1 clathrin adaptor complex by arf1 7.0Å AUTH X.REN,G.G.FARIAS,B.J.CANAGARAJAH,J.S.BONIFACINO,J.H.HURLEYTITL STRUCTURAL BASIS FOR RECRUITMENT AND ACTIVATION OF THE AP-1TITL 2 CLATHRIN ADAPTOR COMPLEX BY ARF1.REF CELL(CAMBRIDGE,MASS.) V. 152 755 2013REFN ISSN 0092-8674PMID 23415225DOI 10.1016/J.CELL.2012.12.042 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 1z68 FAP crystal structure of human fibroblast activation protein alpha 2.6Å AUTH K.AERTGEERTS,I.LEVIN,L.SHI,G.P.SNELL,A.JENNINGS,G.S.PRASAD,AUTH 2 Y.ZHANG,M.L.KRAUS,S.SALAKIAN,V.SRIDHAR,R.WIJNANDS,AUTH 3 M.G.TENNANTTITL STRUCTURAL AND KINETIC ANALYSIS OF THE SUBSTRATE SPECIFICITYTITL 2 OF HUMAN FIBROBLAST ACTIVATION PROTEIN ALPHA.REF J.BIOL.CHEM. V. 280 19441 2005REFN ISSN 0021-9258PMID 15809306DOI 10.1074/JBC.C500092200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 3ygs CASP9 apaf-1 card in complex with prodomain of procaspase-9 2.5Å AUTH H.QIN,S.M.SRINIVASULA,G.WU,T.FERNANDES-ALNEMRI,AUTH 2 E.S.ALNEMRI,Y.SHITITL STRUCTURAL BASIS OF PROCASPASE-9 RECRUITMENT BYTITL 2 THE APOPTOTIC PROTEASE-ACTIVATING FACTOR 1.REF NATURE V. 399 549 1999REFN ISSN 0028-0836PMID 10376594DOI 10.1038/21124 Variant Set Distributions Mapped Variants
General Structure Information 3bpn IL13RA1 crystal structure of the il4-il4r-il13ra ternary complex 3.02Å AUTH S.L.LAPORTE,Z.S.JUO,J.VACLAVIKOVA,L.A.COLF,X.QI,N.M.HELLER,AUTH 2 A.D.KEEGAN,K.C.GARCIATITL MOLECULAR AND STRUCTURAL BASIS OF CYTOKINE RECEPTORTITL 2 PLEIOTROPY IN THE INTERLEUKIN-4/13 SYSTEM.REF CELL(CAMBRIDGE,MASS.) V. 132 259 2008REFN ISSN 0092-8674PMID 18243101DOI 10.1016/J.CELL.2007.12.030 Variant Set Distributions Mapped Variants
General Structure Information 4avp ETV1 crystal structure of the dna-binding domain of human etv1. 1.82Å AUTH C.D.O.COOPER,J.A.NEWMAN,H.AITKENHEAD,C.K.ALLERSTON,AUTH 2 O.GILEADITITL STRUCTURES OF THE ETS DOMAINS OF TRANSCRIPTION FACTORS ETV1,TITL 2 ETV4, ETV5 AND FEV: DETERMINANTS OF DNA BINDING AND REDOXTITL 3 REGULATION BY DISULFIDE BOND FORMATION.REF J.BIOL.CHEM. V. 290 13692 2015REFN ISSN 0021-9258PMID 25866208DOI 10.1074/JBC.M115.646737 Variant […]
General Structure Information 3nbn NOTCH1 crystal structure of a dimer of notch transcription complex trimers on hes1 dna 3.45Å AUTH K.L.ARNETT,M.HASS,D.G.MCARTHUR,M.X.ILAGAN,J.C.ASTER,R.KOPAN,AUTH 2 S.C.BLACKLOWTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO COOPERATIVETITL 2 ASSEMBLY OF DIMERIC NOTCH TRANSCRIPTION COMPLEXES.REF NAT.STRUCT.MOL.BIOL. V. 17 1312 2010REFN ISSN 1545-9993PMID 20972443DOI 10.1038/NSMB.1938 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3alo MAP2K4 crystal structure of human non-phosphorylated mkk4 kinase domain ternary complex with amp-pnp and p38 peptide 2.6Å AUTH T.MATSUMOTO,T.KINOSHITA,Y.KIRII,K.YOKOTA,K.HAMADA,T.TADATITL CRYSTAL STRUCTURES OF MKK4 KINASE DOMAIN REVEAL THATTITL 2 SUBSTRATE PEPTIDE BINDS TO AN ALLOSTERIC SITE AND INDUCES ANTITL 3 AUTO-INHIBITION STATEREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 400 369 2010REFN ISSN 0006-291XPMID 20732303DOI 10.1016/J.BBRC.2010.08.071 Variant […]
General Structure Information 1k5g RANBP1 crystal structure of ran-gdp-alfx-ranbp1-rangap complex 3.1Å AUTH M.J.SEEWALD,C.KORNER,A.WITTINGHOFER,I.R.VETTERTITL RANGAP MEDIATES GTP HYDROLYSIS WITHOUT AN ARGININETITL 2 FINGER.REF NATURE V. 415 662 2002REFN ISSN 0028-0836PMID 11832950DOI 10.1038/415662A Variant Set Distributions Mapped Variants
General Structure Information 4ekc RGS2 structure of human regulator of g protein signaling 2 (rgs2) in complex with murine galpha-q(r183c) 7.4Å AUTH M.R.NANCE,B.KREUTZ,V.M.TESMER,R.STERNE-MARR,T.KOZASA,AUTH 2 J.J.TESMERTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE REGULATOR OF GTITL 2 PROTEIN SIGNALING 2-G ALPHA Q COMPLEX.REF STRUCTURE V. 21 438 2013REFN ISSN 0969-2126PMID 23434405DOI 10.1016/J.STR.2012.12.016 Variant Set Distributions Mapped Variants