General Structure Information 1ya0 SMG7 crystal structure of the n-terminal domain of human smg7 2.55Å AUTH N.FUKUHARA,J.EBERT,L.UNTERHOLZNER,D.LINDNER,AUTH 2 E.IZAURRALDE,E.CONTITITL SMG7 IS A 14-3-3-LIKE ADAPTOR IN THETITL 2 NONSENSE-MEDIATED MRNA DECAY PATHWAY.REF MOL.CELL V. 17 537 2005REFN ISSN 1097-2765PMID 15721257DOI 10.1016/J.MOLCEL.2005.01.010 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2c74 YWHAH 14-3-3 protein eta (human) complexed to peptide 2.7Å AUTH X.YANG,W.H.LEE,F.SOBOTT,E.PAPAGRIGORIOU,C.V.ROBINSON,AUTH 2 J.G.GROSSMANN,M.SUNDSTROM,D.A.DOYLE,J.M.ELKINSTITL STRUCTURAL BASIS FOR PROTEIN-PROTEIN INTERACTIONS IN THETITL 2 14-3-3 PROTEIN FAMILY.REF PROC.NATL.ACAD.SCI.USA V. 103 17237 2006REFN ISSN 0027-8424PMID 17085597DOI 10.1073/PNAS.0605779103 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4j6s YWHAG 14-3-3gamma complexed with the n-terminal sequence of tyrosine hydroxylase (residues 1-43) 3.08Å AUTH A.A.SKJEVIK,M.MILENI,A.BAUMANN,O.HALSKAU,K.TEIGEN,AUTH 2 R.C.STEVENS,A.MARTINEZTITL THE N-TERMINAL SEQUENCE OF TYROSINE HYDROXYLASE IS ATITL 2 CONFORMATIONALLY VERSATILE MOTIF THAT BINDS 14-3-3 PROTEINSTITL 3 AND MEMBRANES.REF J.MOL.BIOL. V. 426 150 2014REFN ISSN 0022-2836PMID 24055376DOI 10.1016/J.JMB.2013.09.012 Variant Set Distributions Mapped Variants
General Structure Information 4j6s YWHAG 14-3-3gamma complexed with the n-terminal sequence of tyrosine hydroxylase (residues 1-43) 3.08Å AUTH A.A.SKJEVIK,M.MILENI,A.BAUMANN,O.HALSKAU,K.TEIGEN,AUTH 2 R.C.STEVENS,A.MARTINEZTITL THE N-TERMINAL SEQUENCE OF TYROSINE HYDROXYLASE IS ATITL 2 CONFORMATIONALLY VERSATILE MOTIF THAT BINDS 14-3-3 PROTEINSTITL 3 AND MEMBRANES.REF J.MOL.BIOL. V. 426 150 2014REFN ISSN 0022-2836PMID 24055376DOI 10.1016/J.JMB.2013.09.012 Variant Set Distributions Mapped Variants
General Structure Information 2br9 YWHAE 14-3-3 protein epsilon (human) complexed to peptide 1.75Å AUTH X.YANG,W.H.LEE,F.SOBOTT,E.PAPAGRIGORIOU,C.V.ROBINSON,AUTH 2 J.G.GROSSMANN,M.SUNDSTROM,D.A.DOYLE,J.M.ELKINSTITL STRUCTURAL BASIS FOR PROTEIN-PROTEIN INTERACTIONS IN THETITL 2 14-3-3 PROTEIN FAMILY.REF PROC.NATL.ACAD.SCI.USA V. 103 17237 2006REFN ISSN 0027-8424PMID 17085597DOI 10.1073/PNAS.0605779103 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2bq0 YWHAB 14-3-3 protein beta (human) 2.5Å AUTH X.YANG,W.H.LEE,F.SOBOTT,E.PAPAGRIGORIOU,AUTH 2 C.V.ROBINSON,J.G.GROSSMANN,M.SUNDSTROM,D.A.DOYLE,AUTH 3 J.M.ELKINSTITL STRUCTURAL BASIS FOR PROTEIN-PROTEIN INTERACTIONSTITL 2 IN THE 14-3-3 PROTEIN FAMILY.REF PROC.NATL.ACAD.SCI.USA V. 103 17237 2006REFN ISSN 0027-8424PMID 17085597DOI 10.1073/PNAS.0605779103 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2btp YWHAQ 14-3-3 protein theta (human) complexed to peptide 2.8Å AUTH X.YANG,W.H.LEE,F.SOBOTT,E.PAPAGRIGORIOU,AUTH 2 C.V.ROBINSON,J.G.GROSSMANN,M.SUNDSTROM,D.A.DOYLE,AUTH 3 J.M.ELKINSTITL STRUCTURAL BASIS FOR PROTEIN-PROTEIN INTERACTIONSTITL 2 IN THE 14-3-3 PROTEIN FAMILY.REF PROC.NATL.ACAD.SCI.USA V. 103 17237 2006REFN ISSN 0027-8424PMID 17085597DOI 10.1073/PNAS.0605779103 Variant Set Distributions Mapped Variants