General Structure Information
| PDB ID | 2bq0 |
| HGNC Gene Label(s) | YWHAB |
| Structure Name | 14-3-3 protein beta (human) |
| Resolution | 2.5Å |
| Reference | AUTH X.YANG,W.H.LEE,F.SOBOTT,E.PAPAGRIGORIOU,AUTH 2 C.V.ROBINSON,J.G.GROSSMANN,M.SUNDSTROM,D.A.DOYLE,AUTH 3 J.M.ELKINSTITL STRUCTURAL BASIS FOR PROTEIN-PROTEIN INTERACTIONSTITL 2 IN THE 14-3-3 PROTEIN FAMILY.REF PROC.NATL.ACAD.SCI.USA V. 103 17237 2006REFN ISSN 0027-8424PMID 17085597DOI 10.1073/PNAS.0605779103 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 230 |
| Number Of SNVs | 39 |
| Number Of Permutations | 21790 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.012 |
| p-value | 0.216 |
COSMIC
| Number Of Residues | 230 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1011 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.667 |
| p-value | 0.311 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 39 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.487 |
| p-value | 0.281 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
