Assessment of Structural Intolerance and Durability
General Structure Information 2odv PLEC crystal structure of a fragment of the plakin domain of plectin, cys to ala mutant. 2.05Å AUTH A.SONNENBERG,A.M.ROJAS,J.M.DE PEREDATITL THE STRUCTURE OF A TANDEM PAIR OF SPECTRIN REPEATS OFTITL 2 PLECTIN REVEALS A MODULAR ORGANIZATION OF THE PLAKIN DOMAIN.REF J.MOL.BIOL. V. 368 1379 2007REFN ISSN 0022-2836PMID 17397861DOI 10.1016/J.JMB.2007.02.090 Variant Set […]
General Structure Information 2odv PLEC crystal structure of a fragment of the plakin domain of plectin, cys to ala mutant. 2.05Å AUTH A.SONNENBERG,A.M.ROJAS,J.M.DE PEREDATITL THE STRUCTURE OF A TANDEM PAIR OF SPECTRIN REPEATS OFTITL 2 PLECTIN REVEALS A MODULAR ORGANIZATION OF THE PLAKIN DOMAIN.REF J.MOL.BIOL. V. 368 1379 2007REFN ISSN 0022-2836PMID 17397861DOI 10.1016/J.JMB.2007.02.090 Variant Set […]
General Structure Information 2epw ZNF268 solution structure of the 24th c2h2 type zinc finger domain of zinc finger protein 268 -1.0Å AUTH W.TANABE,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 24TH C2H2 TYPE ZINCTITL 2 FINGER DOMAIN OF ZINC FINGER PROTEIN 268REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3a77 IRF3 the crystal structure of phosphorylated irf-3 1.8Å AUTH K.TAKAHASI,M.HORIUCHI,K.FUJII,S.NAKAMURA,N.N.NODA,AUTH 2 M.YONEYAMA,T.FUJITA,F.INAGAKITITL SER386 PHOSPHORYLATION OF TRANSCRIPTION FACTOR IRF-3 INDUCESTITL 2 DIMERIZATION AND ASSOCIATION WITH CBP/P300 WITHOUT OVERALLTITL 3 CONFORMATIONAL CHANGE.REF GENES CELLS V. 15 901 2010REFN ISSN 1356-9597PMID 20604809DOI 10.1111/J.1365-2443.2010.01427.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 3u82 PVRL1 binding of herpes simplex virus glycoprotein d to nectin-1 exploits host cell adhesion 3.16Å AUTH N.ZHANG,J.YAN,G.LU,Z.GUO,Z.FAN,J.WANG,Y.SHI,J.QI,G.F.GAOTITL BINDING OF HERPES SIMPLEX VIRUS GLYCOPROTEIN D TO NECTIN-1TITL 2 EXPLOITS HOST CELL ADHESION.REF NAT COMMUN V. 2 577 2011REFN ESSN 2041-1723PMID 22146396DOI 10.1038/NCOMMS1571 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3u82 PVRL1 binding of herpes simplex virus glycoprotein d to nectin-1 exploits host cell adhesion 3.16Å AUTH N.ZHANG,J.YAN,G.LU,Z.GUO,Z.FAN,J.WANG,Y.SHI,J.QI,G.F.GAOTITL BINDING OF HERPES SIMPLEX VIRUS GLYCOPROTEIN D TO NECTIN-1TITL 2 EXPLOITS HOST CELL ADHESION.REF NAT COMMUN V. 2 577 2011REFN ESSN 2041-1723PMID 22146396DOI 10.1038/NCOMMS1571 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3u82 PVRL1 binding of herpes simplex virus glycoprotein d to nectin-1 exploits host cell adhesion 3.16Å AUTH N.ZHANG,J.YAN,G.LU,Z.GUO,Z.FAN,J.WANG,Y.SHI,J.QI,G.F.GAOTITL BINDING OF HERPES SIMPLEX VIRUS GLYCOPROTEIN D TO NECTIN-1TITL 2 EXPLOITS HOST CELL ADHESION.REF NAT COMMUN V. 2 577 2011REFN ESSN 2041-1723PMID 22146396DOI 10.1038/NCOMMS1571 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2l1i HLTF nmr structure of the hltf hiran domain -1.0Å AUTH D.NECULAI,I.BEZSONOVA,J.WEIGELT,C.BOUNTRA,A.EDWARDS,AUTH 2 C.ARROWSMITH,S.DHE-PAGANONTITL NMR STRUCTURE OF THE HLTF HIRAN DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ypd JMJD1C crystal structure of the jumonji domain of human jumonji domain containing 1c protein 2.1Å AUTH M.VOLLMAR,C.JOHANSSON,T.KROJER,C.STRAIN-DAMERELL,S.FROESE,AUTH 2 E.WILLIAMS,D.COUTANDIN,F.VON DELFT,J.WEIGELT,C.H.ARROWSMITH,AUTH 3 C.BOUNTRA,A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE JUMONJI DOMAIN OF HUMAN JUMONJITITL 2 DOMAIN CONTAINING 1C PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3mq4 GRM7 metabotropic glutamate receptor mglur7 complexed with ly341495 antagonist 2.8Å AUTH E.DOBROVETSKY,G.KHUTORESKAYA,A.SEITOVA,H.HE,A.M.EDWARDS,AUTH 2 C.H.ARROWSMITH,C.BOUNTRA,J.WEIGELT,D.COSSAR,A.BOCHKAREVTITL MGLUR7 COMPLEXED WITH LY341495REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants