Assessment of Structural Intolerance and Durability
General Structure Information 3lra LIN7C structural basis for assembling a human tripartite complex dlg1-mpp7- mals3 2.95Å AUTH X.YANG,X.XIE,L.CHEN,H.ZHOU,Z.WANG,W.ZHAO,R.TIAN,R.ZHANG,AUTH 2 C.TIAN,J.LONG,Y.SHENTITL STRUCTURAL BASIS FOR TANDEM L27 DOMAIN-MEDIATEDTITL 2 POLYMERIZATIONREF FASEB J. V. 24 4806 2010REFN ISSN 0892-6638PMID 20702775DOI 10.1096/FJ.10-163857 Variant Set Distributions Mapped Variants
General Structure Information 2l6k TENC1 solution structure of a nonphosphorylated peptide recognizing domain -1.0Å AUTH K.DAI,S.LIAO,J.ZHANG,X.ZHANG,X.TUTITL SOLUTION STRUCTURE OF TENSIN2 SH2 DOMAIN AND ITSTITL 2 PHOSPHOTYROSINE-INDEPENDENT INTERACTION WITH DLC-1REF PLOS ONE V. 6 21965 2011REFN ESSN 1932-6203PMID 21765928DOI 10.1371/JOURNAL.PONE.0021965 Variant Set Distributions Mapped Variants
General Structure Information 4h22 LRRFIP1 crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor lrrfip1 2.89Å AUTH J.B.NGUYEN,Y.MODISTITL CRYSTAL STRUCTURE OF THE DIMERIC COILED-COIL DOMAIN OF THETITL 2 CYTOSOLIC NUCLEIC ACID SENSOR LRRFIP1.REF J.STRUCT.BIOL. V. 181 82 2013REFN ISSN 1047-8477PMID 23099021DOI 10.1016/J.JSB.2012.10.006 Variant Set Distributions Mapped Variants
General Structure Information 2jcn BAK1 the crystal structure of bak1 – a mitochondrial apoptosis regulator 1.8Å AUTH M.MOCHE,P.STENMARK,C.ARROWSMITH,H.BERGLUND,R.BUSAM,AUTH 2 R.COLLINS,A.EDWARDS,U.B.ERICSSON,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,B.M.HALLBERG,L.HOLMBERG SCHIAVONE,AUTH 4 I.JOHANSSON,T.KARLBERG,U.KOSINSKA,T.KOTENYOVA,S.LUNDGREN,AUTH 5 M.E.NILSSON,T.NYMAN,D.OGG,C.PERSSON,J.SAGEMARK,M.SUNDSTROM,AUTH 6 J.UPPENBERG,M.UPSTEN,A.G.THORSELL,S.VAN DEN BERG,J.WEIGELT,AUTH 7 P.NORDLUNDTITL THE CRYSTAL STRUCTURE OF BAK1 – AN APOPTOSIS TRIGGER IN THETITL 2 MITOCHONDRIAL OUTER MEMBRANEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 4hpm BCORL1 pcgf1 ub fold (rawul)/bcorl1 pufd complex 1.85Å AUTH S.E.JUNCO,R.WANG,J.C.GAIPA,A.B.TAYLOR,V.SCHIRF,M.D.GEARHART,AUTH 2 V.J.BARDWELL,B.DEMELER,P.J.HART,C.A.KIMTITL STRUCTURE OF THE POLYCOMB GROUP PROTEIN PCGF1 IN COMPLEXTITL 2 WITH BCOR REVEALS BASIS FOR BINDING SELECTIVITY OF PCGFTITL 3 HOMOLOGS.REF STRUCTURE V. 21 665 2013REFN ISSN 0969-2126PMID 23523425DOI 10.1016/J.STR.2013.02.013 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2oq0 IFI16 crystal structure of the first hin-200 domain of interferon-inducible protein 16 2.0Å AUTH J.C.C.LIAO,R.LAM,M.RAVICHANDRAN,J.MA,W.TEMPEL,N.Y.CHIRGADZE,AUTH 2 C.H.ARROWSMITHTITL CRYSTAL STRUCTURE OF THE FIRST HIN-200 DOMAIN OFTITL 2 INTERFERON-INDUCIBLE PROTEIN 16REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2eny OBSCN solution structure of the ig-like domain (2735-2825) of human obscurin -1.0Å AUTH K.NAGASHIMA,K.IZUMI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IG-LIKE DOMAINTITL 2 (2735-2825) OF HUMAN OBSCURINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2emg ZNF484 solution structure of the c2h2 type zinc finger (region 463- 495) of human zinc finger protein 484 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 463-495) OF HUMAN ZINC FINGER PROTEIN 484REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2vm8 DPYSL2 human crmp-2 crystallised in the presence of mg 1.9Å AUTH V.MAJAVA,N.LOYTYNOJA,W.Q.CHEN,G.LUBEC,P.KURSULATITL CRYSTAL AND SOLUTION STRUCTURE, STABILITY ANDTITL 2 POST- TRANSLATIONAL MODIFICATIONS OF COLLAPSINTITL 3 RESPONSE MEDIATOR PROTEIN 2.REF FEBS J. V. 275 4583 2008REFN ISSN 1742-464XPMID 18699782DOI 10.1111/J.1742-4658.2008.06601.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 4e36 ERAP2 crystal structure of the human endoplasmic reticulum aminopeptidase 2 variant n392k 3.22Å AUTH I.EVNOUCHIDOU,J.BIRTLEY,S.SEREGIN,A.PAPAKYRIAKOU,E.ZERVOUDI,AUTH 2 M.SAMIOTAKI,G.PANAYOTOU,P.GIASTAS,O.PETRAKIS,D.GEORGIADIS,AUTH 3 A.AMALFITANO,E.SARIDAKIS,I.M.MAVRIDIS,E.STRATIKOSTITL A COMMON SINGLE NUCLEOTIDE POLYMORPHISM IN ENDOPLASMICTITL 2 RETICULUM AMINOPEPTIDASE 2 INDUCES A SPECIFICITY SWITCH THATTITL 3 LEADS TO ALTERED ANTIGEN PROCESSING.REF J.IMMUNOL. V. 189 2383 2012REFN ISSN 0022-1767PMID 22837489DOI 10.4049/JIMMUNOL.1200918 Variant […]