Assessment of Structural Intolerance and Durability
General Structure Information 2e9x GINS3 the crystal structure of human gins core complex 2.3Å AUTH K.KAMADA,Y.KUBOTA,T.ARATA,Y.SHINDO,F.HANAOKATITL STRUCTURE OF THE HUMAN GINS COMPLEX AND ITSTITL 2 ASSEMBLY AND FUNCTIONAL INTERFACE IN REPLICATIONTITL 3 INITIATIONREF NAT.STRUCT.MOL.BIOL. V. 14 388 2007REFN ISSN 1545-9993PMID 17417653DOI 10.1038/NSMB1231 Variant Set Distributions Mapped Variants
General Structure Information 2e9x GINS4 the crystal structure of human gins core complex 2.3Å AUTH K.KAMADA,Y.KUBOTA,T.ARATA,Y.SHINDO,F.HANAOKATITL STRUCTURE OF THE HUMAN GINS COMPLEX AND ITSTITL 2 ASSEMBLY AND FUNCTIONAL INTERFACE IN REPLICATIONTITL 3 INITIATIONREF NAT.STRUCT.MOL.BIOL. V. 14 388 2007REFN ISSN 1545-9993PMID 17417653DOI 10.1038/NSMB1231 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2yu8 ZNF347 solution structure of the c2h2 type zinc finger (region 648- 680) of human zinc finger protein 347 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 648-680) OF HUMAN ZINC FINGER PROTEIN 347REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wou TXNDC17 crystal structure of human trp14 1.8Å AUTH J.R.WOO,S.J.KIM,W.JEONG,Y.H.CHO,S.C.LEE,Y.J.CHUNG,AUTH 2 S.G.RHEE,S.E.RYUTITL STRUCTURAL BASIS OF CELLULAR REDOX REGULATION BYTITL 2 HUMAN TRP14REF J.BIOL.CHEM. V. 279 48120 2004REFN ISSN 0021-9258PMID 15355959DOI 10.1074/JBC.M407079200 Variant Set Distributions Mapped Variants
General Structure Information 3edt KLC2 crystal structure of the mutated s328n hklc2 tpr domain 2.7Å AUTH H.ZHU,Y.SHEN,F.MACKENZIE,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF MUTATED S328N TPR DOMAIN OF HUMANTITL 2 KINESIN LIGHT CHAIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4nac RPRD1A crystal structure of the n-terminal domain of p15rs 2.0Å AUTH K.MEI,Z.JIN,F.REN,Y.WANG,Z.CHANG,X.WANGTITL CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF P15RSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ctd ZNF512 solution structure of two zf-c2h2 domains from human zinc finger protein 512 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF TWO ZF-C2H2 DOMAINS FROMTITL 2 HUMAN ZINC FINGER PROTEIN 512REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wgo SORCS2 solution structure of the pkd domain from human vps10 domain-containing receptor sorcs2 -1.0Å AUTH E.CHIKAYAMA,T.KIGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PKD DOMAIN FROM HUMANTITL 2 VPS10 DOMAIN-CONTAINING RECEPTOR SORCS2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3rmu MCEE crystal structure of human methylmalonyl-coa epimerase, mcee 1.8Å AUTH A.CHAIKUAD,E.KRYSZTOFINSKA,D.S.FROESE,W.W.YUE,M.VOLLMAR,AUTH 2 J.R.C.MUNIZ,F.VON DELFT,J.WEIGELT,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,C.BOUNTRA,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF HUMAN METHYLMALONYL-COA EPIMERASE, MCEEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2y9q MKNK1 crystal structure of human erk2 complexed with a mapk docking peptide 1.55Å AUTH A.GARAI,A.ZEKE,G.GOGL,I.TORO,F.FORDOS,H.BLANKENBURG,AUTH 2 T.BARKAI,J.VARGA,A.ALEXA,D.EMIG,M.ALBRECHT,A.REMENYITITL SPECIFICITY OF LINEAR MOTIFS THAT BIND TO A COMMON MITOGEN-TITL 2 ACTIVATED PROTEIN KINASE DOCKING GROOVE.REF SCI. SIGNAL V. 5 74 2012REFN ESSN 1937-9145PMID 23047924DOI 10.1126/SCISIGNAL.2003004 Variant Set Distributions Mapped Variants