Assessment of Structural Intolerance and Durability
General Structure Information 2edp SHROOM4 solution structure of the pdz domain from human shroom family member 4 -1.0Å AUTH H.ENDO,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN FROM HUMANTITL 2 SHROOM FAMILY MEMBER 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3o10 SACS crystal structure of the hepn domain from human sacsin 1.9Å AUTH G.KOZLOV,A.Y.DENISOV,M.GIRARD,M.J.DICAIRE,J.HAMLIN,AUTH 2 P.S.MCPHERSON,B.BRAIS,K.GEHRINGTITL STRUCTURAL BASIS OF DEFECTS IN THE SACSIN HEPN DOMAINTITL 2 RESPONSIBLE FOR AUTOSOMAL RECESSIVE SPASTIC ATAXIA OFTITL 3 CHARLEVOIX-SAGUENAY (ARSACS).REF J.BIOL.CHEM. V. 286 20407 2011REFN ISSN 0021-9258PMID 21507954DOI 10.1074/JBC.M111.232884 Variant Set Distributions Mapped Variants
General Structure Information 1uhp PDZRN3 solution structure of rsgi ruh-005, a pdz domain in human cdna, kiaa1095 -1.0Å AUTH T.HAMADA,Y.MUTO,H.HIROTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-005, A PDZ DOMAINTITL 2 IN HUMAN CDNA, KIAA1095REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3haj PACSIN2 crystal structure of human pacsin2 f-bar domain (p212121 lattice) 2.78Å AUTH Q.WANG,M.V.NAVARRO,G.PENG,E.MOLINELLI,S.LIN GOH,AUTH 2 B.L.JUDSON,K.R.RAJASHANKAR,H.SONDERMANNTITL MOLECULAR MECHANISM OF MEMBRANE CONSTRICTION ANDTITL 2 TUBULATION MEDIATED BY THE F-BAR PROTEINTITL 3 PACSIN/SYNDAPIN.REF PROC.NATL.ACAD.SCI.USA V. 106 12700 2009REFN ISSN 0027-8424PMID 19549836DOI 10.1073/PNAS.0902974106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 2i7t CPSF3 structure of human cpsf-73 2.1Å AUTH C.R.MANDEL,S.KANEKO,H.ZHANG,D.GEBAUER,V.VETHANTHAM,AUTH 2 J.L.MANLEY,L.TONGTITL POLYADENYLATION FACTOR CPSF-73 IS THE PRE-MRNATITL 2 3-END-PROCESSING ENDONUCLEASE.REF NATURE V. 444 953 2006REFN ISSN 0028-0836PMID 17128255DOI 10.1038/NATURE05363 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2r13 CISD1 crystal structure of human mitoneet reveals a novel [2fe- 2s] cluster coordination 1.8Å AUTH X.HOU,R.LIU,S.ROSS,E.J.SMART,H.ZHU,W.GONGTITL CRYSTALLOGRAPHIC STUDIES OF HUMAN MITONEETREF J.BIOL.CHEM. V. 282 33242 2007REFN ISSN 0021-9258PMID 17905743DOI 10.1074/JBC.C700172200 Variant Set Distributions Mapped Variants
General Structure Information 3jyh DPP7 human dipeptidyl peptidase dpp7 2.19Å AUTH E.DOBROVETSKY,A.DONG,A.SEITOVA,L.CROMBETT,S.PAGANON,AUTH 2 D.COSSAR,A.M.EDWARDS,C.H.ARROWSMITH,C.BOUNTRA,J.WEIGELT,AUTH 3 A.HASSEL,L.SHEWCHUK,A.BOCHKAREVTITL HUMAN DIPEPTIDYL PEPTIDASE DPP7REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1wj3 CNTN3 solution structure of the fourth fn3 domain of kiaa1496 protein -1.0Å AUTH K.INOUE,T.NAGASHIMA,N.TOCHIO,T.KIGAWA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FOURTH FN3 DOMAIN OFTITL 2 KIAA1496 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2cqe ZC3H4 solution structure of the zinc-finger domain in kiaa1064 protein -1.0Å AUTH T.SOMEYA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZINC-FINGER DOMAIN INTITL 2 KIAA1064 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mdj ERAP1 er aminopeptidase, erap1, bound to the zinc aminopeptidase inhibitor, bestatin 2.95Å AUTH T.T.NGUYEN,S.C.CHANG,I.EVNOUCHIDOU,I.A.YORK,C.ZIKOS,AUTH 2 K.L.ROCK,A.L.GOLDBERG,E.STRATIKOS,L.J.STERNTITL STRUCTURAL BASIS FOR ANTIGENIC PEPTIDE PRECURSOR PROCESSINGTITL 2 BY THE ENDOPLASMIC RETICULUM AMINOPEPTIDASE ERAP1.REF NAT.STRUCT.MOL.BIOL. V. 18 604 2011REFN ISSN 1545-9993PMID 21478864DOI 10.1038/NSMB.2021 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants