Assessment of Structural Intolerance and Durability
General Structure Information 4nsc MICU1 crystal structure of cbara1 in the apo-form 3.2Å AUTH L.WANG,X.YANG,S.LI,Z.WANG,Y.LIU,J.FENG,Y.ZHU,Y.SHENTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO MICU1 REGULATION OFTITL 2 MITOCHONDRIAL CALCIUM UPTAKE.REF EMBO J. V. 33 594 2014REFN ISSN 0261-4189PMID 24514027DOI 10.1002/EMBJ.201386523 Variant Set Distributions Mapped Variants
General Structure Information 1r8u CITED2 nmr structure of cbp taz1/cited2 complex -1.0Å AUTH R.N.DE GUZMAN,M.A.MARTINEZ-YAMOUT,H.J.DYSON,AUTH 2 P.E.WRIGHTTITL INTERACTION OF THE TAZ1 DOMAIN OF THE CREB-BINDINGTITL 2 PROTEIN WITH THE ACTIVATION DOMAIN OF CITED2:TITL 3 REGULATION BY COMPETITION BETWEEN INTRINSICALLYTITL 4 UNSTRUCTURED LIGANDS FOR NON-IDENTICAL BINDINGTITL 5 SITES.REF J.BIOL.CHEM. V. 279 3042 2004REFN ISSN 0021-9258PMID 14594809DOI […]
General Structure Information 3nw0 NDNL2 crystal structure of mageg1 and nse1 complex 2.92Å AUTH J.M.DOYLE,J.GAO,J.WANG,M.YANG,P.R.POTTSTITL MAGE-RING PROTEIN COMPLEXES COMPRISE A FAMILY OF E3TITL 2 UBIQUITIN LIGASES.REF MOL.CELL V. 39 963 2010REFN ISSN 1097-2765PMID 20864041DOI 10.1016/J.MOLCEL.2010.08.029 Variant Set Distributions Mapped Variants
General Structure Information 2le9 S100A13 ragec2-s100a13 tetrameric complex -1.0Å AUTH S.G.RANI,S.K.MOHAN,C.YUTITL INTERACTION OF S100A13 WITH RECEPTOR FOR ADVANCED GLYCATIONTITL 2 END PRODUCTS (RAGE) C2 DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3c5r BARD1 crystal structure of the bard1 ankyrin repeat domain and its functional consequences 2.0Å AUTH D.FOX,I.LE TRONG,P.RAJAGOPAL,P.S.BRZOVIC,R.E.STENKAMP,AUTH 2 R.E.KLEVITTITL CRYSTAL STRUCTURE OF THE BARD1 ANKYRIN REPEAT DOMAIN AND ITSTITL 2 FUNCTIONAL CONSEQUENCES.REF J.BIOL.CHEM. V. 283 21179 2008REFN ISSN 0021-9258PMID 18480049DOI 10.1074/JBC.M802333200 Variant Set Distributions Mapped Variants
General Structure Information 4gqb WDR77 crystal structure of the human prmt5:mep50 complex 2.06Å AUTH S.ANTONYSAMY,Z.BONDAY,R.M.CAMPBELL,B.DOYLE,Z.DRUZINA,AUTH 2 T.GHEYI,B.HAN,L.N.JUNGHEIM,Y.QIAN,C.RAUCH,M.RUSSELL,AUTH 3 J.M.SAUDER,S.R.WASSERMAN,K.WEICHERT,F.S.WILLARD,A.ZHANG,AUTH 4 S.EMTAGETITL CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX.REF PROC.NATL.ACAD.SCI.USA V. 109 17960 2012REFN ISSN 0027-8424PMID 23071334DOI 10.1073/PNAS.1209814109 Variant Set Distributions Mapped Variants
General Structure Information 1jm7 BARD1 solution structure of the brca1/bard1 ring-domain heterodimer -1.0Å AUTH P.S.BRZOVIC,P.RAJAGOPAL,D.W.HOYT,M.C.KING,AUTH 2 R.E.KLEVITTITL STRUCTURE OF A BRCA1-BARD1 HETERODIMERIC RING-RINGTITL 2 COMPLEX.REF NAT.STRUCT.BIOL. V. 8 833 2001REFN ISSN 1072-8368PMID 11573085DOI 10.1038/NSB1001-833 Variant Set Distributions Mapped Variants
General Structure Information 2okj GAD1 the x-ray crystal structure of the 67kda isoform of glutamic acid decarboxylase (gad67) 2.3Å AUTH G.FENALTI,R.H.P.LAW,A.M.BUCKLE,C.LANGENDORF,K.TUCK,AUTH 2 C.J.ROSADO,N.G.FAUX,K.MAHMOOD,C.S.HAMPE,J.P.BANGA,AUTH 3 M.WILCE,J.SCHMIDBERGER,J.ROSSJOHN,O.EL-KABBANI,AUTH 4 R.N.PIKE,A.I.SMITH,I.R.MACKAY,M.J.ROWLEY,AUTH 5 J.C.WHISSTOCKTITL GABA PRODUCTION BY GLUTAMIC ACID DECARBOXYLASE ISTITL 2 REGULATED BY A DYNAMIC CATALYTIC LOOP.REF NAT.STRUCT.MOL.BIOL. V. 14 280 2007REFN ISSN 1545-9993PMID 17384644DOI 10.1038/NSMB1228 Variant Set Distributions […]
General Structure Information 2kav SCN2A solution structure of the human voltage-gated sodium channel, brain isoform (nav1.2) -1.0Å AUTH V.Z.MILOUSHEV,J.A.LEVINE,M.A.ARBING,J.F.HUNT,G.S.PITT,AUTH 2 A.G.PALMERTITL SOLUTION STRUCTURE OF THE NAV1.2 C-TERMINAL EF-HAND DOMAIN.REF J.BIOL.CHEM. V. 284 6446 2009REFN ISSN 0021-9258PMID 19129176DOI 10.1074/JBC.M807401200 Variant Set Distributions Mapped Variants
General Structure Information 3cuq VPS25 integrated structural and functional model of the human escrt-ii complex 2.61Å AUTH Y.J.IM,J.H.HURLEYTITL INTEGRATED STRUCTURAL MODEL AND MEMBRANE TARGETING MECHANISMTITL 2 OF THE HUMAN ESCRT-II COMPLEXREF DEV.CELL V. 14 902 2008REFN ISSN 1534-5807PMID 18539118DOI 10.1016/J.DEVCEL.2008.04.004 Variant Set Distributions Mapped Variants