Assessment of Structural Intolerance and Durability
General Structure Information 3uk6 RUVBL2 crystal structure of the tip48 (tip49b) hexamer 2.95Å AUTH M.PETUKHOV,A.DAGKESSAMANSKAJA,M.BOMMER,T.BARRETT,I.TSANEVA,AUTH 2 A.YAKIMOV,R.QUEVAL,A.SHVETSOV,M.KHODORKOVSKIY,E.KAS,AUTH 3 M.GRIGORIEVTITL LARGE-SCALE CONFORMATIONAL FLEXIBILITY DETERMINES THETITL 2 PROPERTIES OF AAA+ TIP49 ATPASES.REF STRUCTURE V. 20 1321 2012REFN ISSN 0969-2126PMID 22748767DOI 10.1016/J.STR.2012.05.012 Variant Set Distributions Mapped Variants
General Structure Information 4iqm PUS1 crystal structure of the catalytic domain of human pus1 1.8Å AUTH N.CZUDNOCHOWSKI,A.L.WANG,J.FINER-MOORE,R.M.STROUDTITL IN HUMAN PSEUDOURIDINE SYNTHASE 1 (HPUS1), A C-TERMINALTITL 2 HELICAL INSERT BLOCKS TRNA FROM BINDING IN THE SAMETITL 3 ORIENTATION AS IN THE PUS1 BACTERIAL HOMOLOGUE TRUA,TITL 4 CONSISTENT WITH THEIR DIFFERENT TARGET SELECTIVITIES.REF J.MOL.BIOL. V. 425 3875 […]
General Structure Information 1v27 RIMS2 solution structure of the first c2 domain of rim2 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OF RIM2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3dyt SNX9 crystal structure of snx9px-bar (230-595), c2221 2.08Å AUTH Q.WANG,H.Y.KAAN,R.N.HOODA,S.L.GOH,H.SONDERMANNTITL STRUCTURE AND PLASTICITY OF ENDOPHILIN AND SORTINGTITL 2 NEXIN 9.REF STRUCTURE V. 16 1574 2008REFN ISSN 0969-2126PMID 18940612DOI 10.1016/J.STR.2008.07.016 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3rpn GSTK1 crystal structure of human kappa class glutathione transferase in complex with s-hexylglutathione 1.9Å AUTH B.WANG,Y.PENG,T.ZHANG,J.DINGTITL CRYSTAL STRUCTURES AND KINETIC STUDIES OF HUMAN KAPPA CLASSTITL 2 GLUTATHIONE TRANSFERASE PROVIDE INSIGHTS INTO THE CATALYTICTITL 3 MECHANISM.REF BIOCHEM.J. V. 439 215 2011REFN ISSN 0264-6021PMID 21728995DOI 10.1042/BJ20110753 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1pc2 FIS1 solution structure of human mitochondria fission protein fis1 -1.0Å AUTH M.SUZUKI,S.Y.JEONG,M.KARBOWSKI,R.J.YOULE,N.TJANDRATITL THE SOLUTION STRUCTURE OF HUMAN MITOCHONDRIATITL 2 FISSION PROTEIN FIS1 REVEALS A NOVEL TPR-LIKETITL 3 HELIX BUNDLEREF J.MOL.BIOL. V. 334 445 2003REFN ISSN 0022-2836PMID 14623186DOI 10.1016/J.JMB.2003.09.064 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3l4g FARSA crystal structure of homo sapiens cytoplasmic phenylalanyl-trna synthetase 3.3Å AUTH I.FINAROV,N.MOOR,N.KESSLER,L.KLIPCAN,M.G.SAFROTITL STRUCTURE OF HUMAN CYTOSOLIC PHENYLALANYL-TRNA SYNTHETASE:TITL 2 EVIDENCE FOR KINGDOM-SPECIFIC DESIGN OF THE ACTIVE SITESTITL 3 AND TRNA BINDING PATTERNS.REF STRUCTURE V. 18 343 2010REFN ISSN 0969-2126PMID 20223217DOI 10.1016/J.STR.2010.01.002 Variant Set Distributions Mapped Variants
General Structure Information 2zmf PDE10A crystal structure of the c-terminal gaf domain of human phosphodiesterase 10a 2.1Å AUTH N.HANDA,E.MIZOHATA,S.KISHISHITA,M.TOYAMA,S.MORITA,AUTH 2 T.UCHIKUBO-KAMO,R.AKASAKA,K.OMORI,J.KOTERA,T.TERADA,AUTH 3 M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE GAF-B DOMAIN FROM HUMANTITL 2 PHOSPHODIESTERASE 10A COMPLEXED WITH ITS LIGAND, CAMPREF J.BIOL.CHEM. V. 283 19657 2008REFN ISSN 0021-9258PMID 18477562DOI 10.1074/JBC.M800595200 Variant Set Distributions Mapped Variants
General Structure Information 2k9a ARL2BP the solution structure of the arl2 effector, bart -1.0Å AUTH L.K.BAILEY,L.J.CAMPBELL,K.A.EVETTS,K.LITTLEFIELD,AUTH 2 E.RAJENDRA,D.NIETLISPACH,D.OWEN,H.R.MOTTTITL THE STRUCTURE OF BINDER OF ARL2 (BART) REVEALS ATITL 2 NOVEL G PROTEIN BINDING DOMAIN: IMPLICATIONS FORTITL 3 FUNCTION.REF J.BIOL.CHEM. V. 284 992 2009REFN ISSN 0021-9258PMID 18981177DOI 10.1074/JBC.M806167200 Variant Set Distributions Mapped Variants
General Structure Information 1tvg HSPB11 x-ray structure of human pp25 gene product, hspc034. northeast structural genomics target hr1958. 1.6Å AUTH T.A.RAMELOT,S.RAMAN,A.P.KUZIN,R.XIAO,L.C.MA,AUTH 2 T.B.ACTON,J.F.HUNT,G.T.MONTELIONE,D.BAKER,AUTH 3 M.A.KENNEDYTITL IMPROVING NMR PROTEIN STRUCTURE QUALITY BY ROSETTATITL 2 REFINEMENT: A MOLECULAR REPLACEMENT STUDY.REF PROTEINS V. 75 147 2009REFN ISSN 0887-3585PMID 18816799DOI 10.1002/PROT.22229 Variant Set Distributions Mapped Variants