Assessment of Structural Intolerance and Durability
General Structure Information 2lxl VTA1 lip5(mit)2 -1.0Å AUTH J.J.SKALICKY,J.ARII,D.M.WENZEL,W.M.STUBBLEFIELD,A.KATSUYAMA,AUTH 2 N.T.UTER,M.BAJOREK,D.G.MYSZKA,W.I.SUNDQUISTTITL INTERACTIONS OF THE HUMAN LIP5 REGULATORY PROTEIN WITHTITL 2 ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT.REF J.BIOL.CHEM. V. 287 43910 2012REFN ISSN 0021-9258PMID 23105106DOI 10.1074/JBC.M112.417899 Variant Set Distributions Mapped Variants
General Structure Information 3n2n ANTXR1 the crystal structure of tumor endothelial marker 8 (tem8) extracellular domain 1.8Å AUTH S.FU,X.TONG,C.CAI,Y.ZHAO,Y.WU,Y.LI,J.XU,X.C.ZHANG,L.XU,AUTH 2 W.CHEN,Z.RAOTITL THE STRUCTURE OF TUMOR ENDOTHELIAL MARKER 8 (TEM8)TITL 2 EXTRACELLULAR DOMAIN AND IMPLICATIONS FOR ITS RECEPTORTITL 3 FUNCTION FOR RECOGNIZING ANTHRAX TOXIN.REF PLOS ONE V. 5 E1120 2010REFN ESSN 1932-6203PMID 20585457DOI 10.1371/JOURNAL.PONE.0011203 Variant Set […]
General Structure Information 2cqm MRPL17 solution structure of the mitochondrial ribosomal protein l17 isolog -1.0Å AUTH S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE MITOCHONDRIAL RIBOSOMALTITL 2 PROTEIN L17 ISOLOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1p9o PPCS crystal structure of phosphopantothenoylcysteine synthetase 2.3Å AUTH N.MANOJ,E.STRAUSS,T.P.BEGLEY,S.E.EALICKTITL STRUCTURE OF HUMAN PHOSPHOPANTOTHENOYLCYSTEINETITL 2 SYNTHETASE AT 2.3 A RESOLUTION.REF STRUCTURE V. 11 927 2003REFN ISSN 0969-2126PMID 12906824DOI 10.1016/S0969-2126(03)00146-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4b4o SDR39U1 crystal structure of human epimerase family protein sdr39u1 (isoform2) with nadph 2.7Å AUTH M.VOLLMAR,J.R.C.MUNIZ,N.SHAFQAT,S.PICAUD,T.KROJER,AUTH 2 A.CHAIKUAD,A.C.W.PIKE,W.W.YUE,P.FILIPPAKOPOULOS,AUTH 3 K.L.KAVANAGH,F.VON DELFT,J.WEIGELT,C.H.ARROWSMITH,C.BOUNTRA,AUTH 4 A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN EPIMERASE FAMILY PROTEIN SDR39U1TITL 2 (ISOFORM2) WITH NADPHREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 1ujt ROBO2 solution structure of the second fibronectin type iii domain of human kiaa1568 protein -1.0Å AUTH N.TOCHIO,S.KOSHIBA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND FIBRONECTIN TYPETITL 2 III DOMAIN OF HUMAN KIAA1568 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3hl2 SEPSECS the crystal structure of the human sepsecs-trnasec complex 2.81Å AUTH S.PALIOURA,R.L.SHERRER,T.A.STEITZ,D.SOLL,AUTH 2 M.SIMONOVICTITL THE HUMAN SEPSECS-TRNASEC COMPLEX REVEALS THETITL 2 MECHANISM OF SELENOCYSTEINE FORMATION.REF SCIENCE V. 325 321 2009REFN ISSN 0036-8075PMID 19608919DOI 10.1126/SCIENCE.1173755 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3l4g FARSB crystal structure of homo sapiens cytoplasmic phenylalanyl-trna synthetase 3.3Å AUTH I.FINAROV,N.MOOR,N.KESSLER,L.KLIPCAN,M.G.SAFROTITL STRUCTURE OF HUMAN CYTOSOLIC PHENYLALANYL-TRNA SYNTHETASE:TITL 2 EVIDENCE FOR KINGDOM-SPECIFIC DESIGN OF THE ACTIVE SITESTITL 3 AND TRNA BINDING PATTERNS.REF STRUCTURE V. 18 343 2010REFN ISSN 0969-2126PMID 20223217DOI 10.1016/J.STR.2010.01.002 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1ixd CYLD solution structure of the cap-gly domain from human cylindromatosis tomour-suppressor cyld -1.0Å AUTH K.SAITO,T.KIGAWA,S.KOSHIBA,K.SATO,Y.MATSUO,AUTH 2 A.SAKAMOTO,T.TAKAGI,M.SHIROUZU,T.YABUKI,E.NUNOKAWA,AUTH 3 E.SEKI,T.MATSUDA,M.AOKI,Y.MIYATA,N.HIRAKAWA,AUTH 4 M.INOUE,T.TERADA,T.NAGASE,R.KIKUNO,M.NAKAYAMA,AUTH 5 O.OHARA,A.TANAKA,S.YOKOYAMATITL THE CAP-GLY DOMAIN OF CYLD ASSOCIATES WITH THETITL 2 PROLINE-RICH SEQUENCE IN NEMO/IKKGAMMAREF STRUCTURE V. 12 1719 2004REFN ISSN 0969-2126PMID 15341735DOI 10.1016/J.STR.2004.07.012 Variant Set Distributions Mapped Variants
General Structure Information 3t6j DPP3 structure of human dppiii in complex with the opioid peptide tynorphin, at 3.0 angstroms 2.98Å AUTH G.A.BEZERRA,E.DOBROVETSKY,R.VIERTLMAYR,A.DONG,A.BINTER,AUTH 2 M.ABRAMIC,P.MACHEROUX,S.DHE-PAGANON,K.GRUBERTITL ENTROPY-DRIVEN BINDING OF OPIOID PEPTIDES INDUCES A LARGETITL 2 DOMAIN MOTION IN HUMAN DIPEPTIDYL PEPTIDASE III.REF PROC.NATL.ACAD.SCI.USA V. 109 6525 2012REFN ISSN 0027-8424PMID 22493238DOI 10.1073/PNAS.1118005109 Variant Set Distributions Ripley’s K Analysis […]