Assessment of Structural Intolerance and Durability
General Structure Information 2y4t DNAJC3 crystal structure of the human co-chaperone p58(ipk) 3.0Å AUTH M.SVARD,E.I.BITEROVA,J.-M.BOURHIS,J.E.GUYTITL THE CRYSTAL STRUCTURE OF THE HUMAN CO-CHAPERONE P58IPKREF PLOS ONE V. 6 22337 2011REFN ISSN 1932-6203PMID 21799829DOI 10.1371/JOURNAL.PONE.0022337 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4a04 TBX1 structure of the dna-bound t-box domain of human tbx1, a transcription factor associated with the digeorge syndrome 2.58Å AUTH K.EL OMARI,J.DE MESMAEKER,D.KARIA,H.GINN,S.BHATTACHARYA,AUTH 2 E.J.MANCINITITL STRUCTURE OF THE DNA-BOUND T-BOX DOMAIN OF HUMAN TBX1, ATITL 2 TRANSCRIPTION FACTOR ASSOCIATED WITH THE DIGEORGE SYNDROMEREF PROTEINS V. 80 655 2012REFN ISSN 0887-3585PMID 22095455DOI […]
General Structure Information 4b4c CHD1 crystal structure of the dna-binding domain of human chd1. 1.62Å AUTH C.K.ALLERSTON,C.D.O.COOPER,L.SHRESTHA,M.VOLLMAR,AUTH 2 N.BURGESS-BROWN,W.W.YUE,E.P.CARPENTER,C.H.ARROWSMITH,AUTH 3 A.EDWARDS,C.BOUNTRA,F.VON DELFT,O.GILEADITITL CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF HUMAN CHD1.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3f8u TAPBP tapasin/erp57 heterodimer 2.6Å AUTH G.DONG,P.A.WEARSCH,D.R.PEAPER,P.CRESSWELL,K.M.REINISCHTITL INSIGHTS INTO MHC CLASS I PEPTIDE LOADING FROM THE STRUCTURETITL 2 OF THE TAPASIN-ERP57 THIOL OXIDOREDUCTASE HETERODIMER.REF IMMUNITY V. 30 21 2009REFN ISSN 1074-7613PMID 19119025DOI 10.1016/J.IMMUNI.2008.10.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2epa KLF10 solution structure of the first and second zf-c2h2 domains from human krueppel-like factor 10 -1.0Å AUTH K.IZUMI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST AND SECOND ZF-C2H2TITL 2 DOMAINS FROM HUMAN KRUEPPEL-LIKE FACTOR 10REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ce8 TLE1 an eh1 peptide bound to the groucho-tle wd40 domain. 2.03Å AUTH B.H.JENNINGS,L.M.PICKLES,S.M.WAINWRIGHT,S.M.ROE,L.H.PEARL,AUTH 2 D.ISH-HOROWICZTITL MOLECULAR RECOGNITION OF TRANSCRIPTIONAL REPRESSOR MOTIFSTITL 2 BY THE WD DOMAIN OF THE GROUCHO/TLE COREPRESSOR.REF MOL.CELL V. 22 645 2006REFN ISSN 1097-2765PMID 16762837DOI 10.1016/J.MOLCEL.2006.04.024 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 4k0v TEK structural basis for angiopoietin-1 mediated signaling initiation 4.51Å AUTH X.YU,T.C.SEEGAR,A.C.DALTON,D.TZVETKOVA-ROBEV,Y.GOLDGUR,AUTH 2 K.R.RAJASHANKAR,D.B.NIKOLOV,W.A.BARTONTITL STRUCTURAL BASIS FOR ANGIOPOIETIN-1-MEDIATED SIGNALINGTITL 2 INITIATION.REF PROC.NATL.ACAD.SCI.USA V. 110 7205 2013REFN ISSN 0027-8424PMID 23592718DOI 10.1073/PNAS.1216890110 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1x4g TIAL1 solution structure of rrm domain in nucleolysin tiar -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF RRM DOMAIN IN NUCLEOLYSINTITL 2 TIARREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1p32 C1QBP crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein 2.25Å AUTH J.JIANG,Y.ZHANG,A.R.KRAINER,R.M.XUTITL CRYSTAL STRUCTURE OF HUMAN P32, A DOUGHNUT-SHAPEDTITL 2 ACIDIC MITOCHONDRIAL MATRIX PROTEIN.REF PROC.NATL.ACAD.SCI.USA V. 96 3572 1999REFN ISSN 0027-8424PMID 10097078DOI 10.1073/PNAS.96.7.3572 Variant Set Distributions Mapped Variants
General Structure Information 1aw0 ATP7A fourth metal-binding domain of the menkes copper- transporting atpase, nmr, 20 structures -1.0Å AUTH J.GITSCHIER,B.MOFFAT,D.REILLY,W.I.WOOD,AUTH 2 W.J.FAIRBROTHERTITL SOLUTION STRUCTURE OF THE FOURTH METAL-BINDINGTITL 2 DOMAIN FROM THE MENKES COPPER-TRANSPORTING ATPASE.REF NAT.STRUCT.BIOL. V. 5 47 1998REFN ISSN 1072-8368PMID 9437429DOI 10.1038/NSB0198-47 Variant Set Distributions Mapped Variants