General Structure Information
| PDB ID | 2y4t |
| HGNC Gene Label(s) | DNAJC3 |
| Structure Name | crystal structure of the human co-chaperone p58(ipk) |
| Resolution | 3.0Å |
| Reference | AUTH M.SVARD,E.I.BITEROVA,J.-M.BOURHIS,J.E.GUYTITL THE CRYSTAL STRUCTURE OF THE HUMAN CO-CHAPERONE P58IPKREF PLOS ONE V. 6 22337 2011REFN ISSN 1932-6203PMID 21799829DOI 10.1371/JOURNAL.PONE.0022337 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 421 |
| Number Of SNVs | 88 |
| Number Of Permutations | 72479 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.046 |
| p-value | 0.544 |
COSMIC
| Number Of Residues | 421 |
| Number Of SNVs | 5 |
| Number Of Permutations | 4051 |
| Optimal Distance Threshold | 32.0 |
| K Statistic | 0.2 |
| p-value | 0.745 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 88 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 40.0 |
| K Statistic | -0.344 |
| p-value | 0.386 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis

