Assessment of Structural Intolerance and Durability
General Structure Information 4gwr PDIA6 crystal structure of the second catalytic domain of protein disulfide isomerase p5 1.81Å AUTH R.VINAIK,G.KOZLOV,K.GEHRINGTITL TO BE PUBLISHEDREF TO BE PUBLISHED 2013REFN Variant Set Distributions Mapped Variants
General Structure Information 4gwr PDIA6 crystal structure of the second catalytic domain of protein disulfide isomerase p5 1.81Å AUTH R.VINAIK,G.KOZLOV,K.GEHRINGTITL TO BE PUBLISHEDREF TO BE PUBLISHED 2013REFN Variant Set Distributions Mapped Variants
General Structure Information 3sde NONO crystal structure of a paraspeckle-protein heterodimer, pspc1/nono 1.9Å AUTH D.M.PASSON,M.LEE,O.RACKHAM,W.A.STANLEY,A.SADOWSKA,AUTH 2 A.FILIPOVSKA,A.H.FOX,C.S.BONDTITL STRUCTURE OF THE HETERODIMER OF HUMAN NONO AND PARASPECKLETITL 2 PROTEIN COMPONENT 1 AND ANALYSIS OF ITS ROLE IN SUBNUCLEARTITL 3 BODY FORMATION.REF PROC.NATL.ACAD.SCI.USA V. 109 4846 2012REFN ISSN 0027-8424PMID 22416126DOI 10.1073/PNAS.1120792109 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3sde NONO crystal structure of a paraspeckle-protein heterodimer, pspc1/nono 1.9Å AUTH D.M.PASSON,M.LEE,O.RACKHAM,W.A.STANLEY,A.SADOWSKA,AUTH 2 A.FILIPOVSKA,A.H.FOX,C.S.BONDTITL STRUCTURE OF THE HETERODIMER OF HUMAN NONO AND PARASPECKLETITL 2 PROTEIN COMPONENT 1 AND ANALYSIS OF ITS ROLE IN SUBNUCLEARTITL 3 BODY FORMATION.REF PROC.NATL.ACAD.SCI.USA V. 109 4846 2012REFN ISSN 0027-8424PMID 22416126DOI 10.1073/PNAS.1120792109 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3sde NONO crystal structure of a paraspeckle-protein heterodimer, pspc1/nono 1.9Å AUTH D.M.PASSON,M.LEE,O.RACKHAM,W.A.STANLEY,A.SADOWSKA,AUTH 2 A.FILIPOVSKA,A.H.FOX,C.S.BONDTITL STRUCTURE OF THE HETERODIMER OF HUMAN NONO AND PARASPECKLETITL 2 PROTEIN COMPONENT 1 AND ANALYSIS OF ITS ROLE IN SUBNUCLEARTITL 3 BODY FORMATION.REF PROC.NATL.ACAD.SCI.USA V. 109 4846 2012REFN ISSN 0027-8424PMID 22416126DOI 10.1073/PNAS.1120792109 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 2qa5 SEPT2 crystal structure of sept2 g-domain 3.4Å AUTH M.SIRAJUDDIN,M.FARKASOVSKY,F.HAUER,D.KUHLMANN,AUTH 2 I.G.MACARA,M.WEYAND,H.STARK,A.WITTINGHOFERTITL STRUCTURAL INSIGHT INTO FILAMENT FORMATION BYTITL 2 MAMMALIAN SEPTINS.REF NATURE V. 449 311 2007REFN ISSN 0028-0836PMID 17637674DOI 10.1038/NATURE06052 Variant Set Distributions Mapped Variants
General Structure Information 2qa5 SEPT2 crystal structure of sept2 g-domain 3.4Å AUTH M.SIRAJUDDIN,M.FARKASOVSKY,F.HAUER,D.KUHLMANN,AUTH 2 I.G.MACARA,M.WEYAND,H.STARK,A.WITTINGHOFERTITL STRUCTURAL INSIGHT INTO FILAMENT FORMATION BYTITL 2 MAMMALIAN SEPTINS.REF NATURE V. 449 311 2007REFN ISSN 0028-0836PMID 17637674DOI 10.1038/NATURE06052 Variant Set Distributions Mapped Variants
General Structure Information 2qa5 SEPT2 crystal structure of sept2 g-domain 3.4Å AUTH M.SIRAJUDDIN,M.FARKASOVSKY,F.HAUER,D.KUHLMANN,AUTH 2 I.G.MACARA,M.WEYAND,H.STARK,A.WITTINGHOFERTITL STRUCTURAL INSIGHT INTO FILAMENT FORMATION BYTITL 2 MAMMALIAN SEPTINS.REF NATURE V. 449 311 2007REFN ISSN 0028-0836PMID 17637674DOI 10.1038/NATURE06052 Variant Set Distributions Mapped Variants
General Structure Information 2wnt RPS6KA1 crystal structure of the human ribosomal protein s6 kinase 2.4Å AUTH J.R.C.MUNIZ,J.M.ELKINS,J.WANG,E.UGOCHUKWU,E.SALAH,AUTH 2 O.KING,S.PICAUD,F.VON DELFT,C.BOUNTRA,AUTH 3 C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,S.KNAPPTITL CRYSTAL STRUCTURE OF THE HUMAN RIBOSOMAL PROTEINTITL 2 S6 KINASEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1×61 TRIP6 solution structure of the first lim domain of thyroid receptor interacting protein 6 (trip6) -1.0Å AUTH X.R.QIN,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST LIM DOMAIN OFTITL 2 THYROID RECEPTOR INTERACTING PROTEIN 6 (TRIP6)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants