Assessment of Structural Intolerance and Durability
General Structure Information 2ep6 MCTP2 solution structure of the second c2 domain from human mctp2 protein -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND C2 DOMAIN FROMTITL 2 HUMAN MCTP2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4gao DCUN1D2 dcnl complex with n-terminally acetylated nedd8 e2 peptide 3.28Å AUTH J.K.MONDA,D.C.SCOTT,D.J.MILLER,J.LYDEARD,D.KING,J.W.HARPER,AUTH 2 E.J.BENNETT,B.A.SCHULMANTITL STRUCTURAL CONSERVATION OF DISTINCTIVE N-TERMINALTITL 2 ACETYLATION-DEPENDENT INTERACTIONS ACROSS A FAMILY OFTITL 3 MAMMALIAN NEDD8 LIGATION ENZYMES.REF STRUCTURE V. 21 42 2013REFN ISSN 0969-2126PMID 23201271DOI 10.1016/J.STR.2012.10.013 Variant Set Distributions Mapped Variants
General Structure Information 3o46 MPP7 crystal structure of the pdz domain of mpp7 1.3Å AUTH L.NEDYALKOVA,Y.TONG,W.TEMPEL,N.ZHONG,X.GUAN,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF MPP7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2rpp MBNL2 solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2 -1.0Å AUTH F.HE,W.DANG,C.ABE,K.TSUDA,M.INOUE,S.WATANABE,AUTH 2 N.KOBAYASHI,T.KIGAWA,T.MATSUDA,T.YABUKI,M.AOKI,AUTH 3 E.SEKI,T.HARADA,Y.TOMABECHI,T.TERADA,M.SHIROUZU,AUTH 4 A.TANAKA,P.GUNTERT,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA BINDING DOMAIN INTITL 2 THE HUMAN MUSCLEBLIND-LIKE PROTEIN 2REF PROTEIN SCI. V. 18 80 2009REFN ISSN 0961-8368PMID 19177353DOI 10.1002/PRO.17 Variant Set Distributions Mapped Variants
General Structure Information 2w4o CAMK4 crystal structure of human camk4 in complex with 4-amino( sulfamoyl-phenylamino)-triazole-carbothioic acid (2,6- difluoro-phenyl)-amide) 2.17Å AUTH J.R.C.MUNIZ,P.RELLOS,O.GILEADI,O.FEDOROV,P.FILIPPAKOPOULOS,AUTH 2 E.SALAH,A.PIKE,C.PHILLIPS,F.NIESEN,L.SHRESTHA,AUTH 3 N.BURGESS-BROWN,A.BULLOCK,G.BERRIDGE,F.VON DELFT,AUTH 4 A.M.EDWARDS,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,S.KNAPPTITL CRYSTAL STRUCTURE OF HUMAN CAMK4 IN COMPLEX WITHTITL 2 4-AMINO(SULFAMOYL-PHENYLAMINO)-TRIAZOLE- CARBOTHIOIC ACIDTITL 3 (2,6-DIFLUORO-PHENYL)-AMIDE)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3k9j SETMAR transposase domain of metnase 1.9Å AUTH K.D.GOODWIN,H.HE,T.IMASAKI,S.H.LEE,M.M.GEORGIADISTITL CRYSTAL STRUCTURE OF THE HUMAN HSMAR1-DERIVED TRANSPOSASETITL 2 DOMAIN IN THE DNA REPAIR ENZYME METNASE.REF BIOCHEMISTRY V. 49 5705 2010REFN ISSN 0006-2960PMID 20521842DOI 10.1021/BI100171X Variant Set Distributions Mapped Variants
General Structure Information 4btm TTBK1 ttbk1 in complex with inhibitor 2.54Å AUTH Y.XUE,P.T.WAN,P.HILLERTZ,F.SCHWEIKART,Y.ZHAO,L.WISSLER,AUTH 2 N.DEKKERTITL X-RAY STRUCTURAL ANALYSIS OF TAU-TUBULIN KINASE 1 AND ITSTITL 2 INTERACTIONS WITH SMALL MOLECULAR INHIBITORS.REF CHEMMEDCHEM V. 8 1846 2013REFN ISSN 1860-7179PMID 24039150DOI 10.1002/CMDC.201300274 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2ega SH3PXD2A solution structure of the first sh3 domain from human kiaa0418 protein -1.0Å AUTH K.INOUE,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST SH3 DOMAIN FROMTITL 2 HUMAN KIAA0418 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2h8k SULT1C3 human sulfotranferase sult1c3 in complex with pap 3.2Å AUTH A.ALLALI-HASSANI,P.W.PAN,L.DOMBROVSKI,AUTH 2 R.NAJMANOVICH,W.TEMPEL,A.DONG,P.LOPPNAU,F.MARTIN,AUTH 3 J.THORNTON,J.THONTON,A.M.EDWARDS,A.BOCHKAREV,AUTH 4 A.N.PLOTNIKOV,M.VEDADI,C.H.ARROWSMITHTITL STRUCTURAL AND CHEMICAL PROFILING OF THE HUMANTITL 2 CYTOSOLIC SULFOTRANSFERASES.REF PLOS BIOL. V. 5 E97 2007REFN ISSN 1544-9173PMID 17425406DOI 10.1371/JOURNAL.PBIO.0050097 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2ytp ZNF484 solution structure of the c2h2 type zinc finger (region 687- 719) of human zinc finger protein 484 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 687-719) OF HUMAN ZINC FINGER PROTEIN 484REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants