General Structure Information
| PDB ID | 4btm |
| HGNC Gene Label(s) | TTBK1 |
| Structure Name | ttbk1 in complex with inhibitor |
| Resolution | 2.54Å |
| Reference | AUTH Y.XUE,P.T.WAN,P.HILLERTZ,F.SCHWEIKART,Y.ZHAO,L.WISSLER,AUTH 2 N.DEKKERTITL X-RAY STRUCTURAL ANALYSIS OF TAU-TUBULIN KINASE 1 AND ITSTITL 2 INTERACTIONS WITH SMALL MOLECULAR INHIBITORS.REF CHEMMEDCHEM V. 8 1846 2013REFN ISSN 1860-7179PMID 24039150DOI 10.1002/CMDC.201300274 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 293 |
| Number Of SNVs | 25 |
| Number Of Permutations | 3221 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.103 |
| p-value | 0.154 |
COSMIC
| Number Of Residues | 293 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1375 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.048 |
| p-value | 0.638 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.133 |
| p-value | 0.686 |