Assessment of Structural Intolerance and Durability
General Structure Information 4nod TFAM distinct structural features of tfam drive mitochondrial dna packaging versus transcriptional activation 2.9Å AUTH H.B.NGO,G.A.LOVELY,R.PHILLIPS,D.C.CHANTITL DISTINCT STRUCTURAL FEATURES OF TFAM DRIVE MITOCHONDRIAL DNATITL 2 PACKAGING VERSUS TRANSCRIPTIONAL ACTIVATION.REF NAT COMMUN V. 5 3077 2014REFN ESSN 2041-1723PMID 24435062DOI 10.1038/NCOMMS4077 Variant Set Distributions Mapped Variants
General Structure Information 4fmd RAB1A espg-rab1 complex structure at 3.05 a 3.05Å AUTH N.DONG,Y.ZHU,Q.LU,L.HU,Y.ZHENG,F.SHAOTITL STRUCTURALLY DISTINCT BACTERIAL TBC-LIKE GAPS LINK ARFTITL 2 GTPASE TO RAB1 INACTIVATION TO COUNTERACT HOST DEFENSES.REF CELL(CAMBRIDGE,MASS.) V. 150 1029 2012REFN ISSN 0092-8674PMID 22939626DOI 10.1016/J.CELL.2012.06.050 Variant Set Distributions Mapped Variants
General Structure Information 3cpf EIF5A crystal structure of human eukaryotic translation initiation factor eif5a 2.5Å AUTH Y.TONG,I.PARK,B.S.HONG,L.NEDYALKOVA,W.TEMPEL,H.W.PARKTITL CRYSTAL STRUCTURE OF HUMAN EIF5A1: INSIGHT INTO FUNCTIONALTITL 2 SIMILARITY OF HUMAN EIF5A1 AND EIF5A2.REF PROTEINS V. 75 1040 2009REFN ISSN 0887-3585PMID 19280598DOI 10.1002/PROT.22378 Variant Set Distributions Mapped Variants
General Structure Information 3p4f WDR5 structural and biochemical insights into mll1 core complex assembly and regulation. 2.35Å AUTH V.AVDIC,P.ZHANG,S.LANOUETTE,A.GROULX,V.TREMBLAY,J.BRUNZELLE,AUTH 2 J.-F.COUTURETITL STRUCTURAL AND BIOCHEMICAL INSIGHTS INTO MLL1 CORE COMPLEXTITL 2 ASSEMBLY.REF STRUCTURE V. 19 101 2011REFN ISSN 0969-2126PMID 21220120DOI 10.1016/J.STR.2010.09.022 Variant Set Distributions Mapped Variants
General Structure Information 3i4r NUP107 nup107(aa658-925)/nup133(aa517-1156) complex, h.sapiens 3.53Å AUTH J.R.WHITTLE,T.U.SCHWARTZTITL ARCHITECTURAL NUCLEOPORINS NUP157/170 AND NUP133TITL 2 ARE STRUCTURALLY RELATED AND DESCEND FROM A SECONDTITL 3 ANCESTRAL ELEMENT.REF J.BIOL.CHEM. V. 284 28442 2009REFN ISSN 0021-9258PMID 19674973DOI 10.1074/JBC.M109.023580 Variant Set Distributions Mapped Variants
General Structure Information 2zu6 EIF4A1 crystal structure of the eif4a-pdcd4 complex 2.8Å AUTH J.H.CHANG,Y.H.CHO,S.Y.SOHN,J.M.CHOI,A.KIM,Y.C.KIM,AUTH 2 S.K.JANG,Y.CHOTITL CRYSTAL STRUCTURE OF THE EIF4A-PDCD4 COMPLEXREF PROC.NATL.ACAD.SCI.USA V. 106 3148 2009REFN ISSN 0027-8424PMID 19204291DOI 10.1073/PNAS.0808275106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2p3w HTRA3 crystal structure of the htra3 pdz domain bound to a phage-derived ligand (fgrwv) 1.7Å AUTH S.T.RUNYON,Y.ZHANG,B.A.APPLETON,S.L.SAZINSKY,P.WU,B.PAN,AUTH 2 C.WIESMANN,N.J.SKELTON,S.S.SIDHUTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE PDZ DOMAINS OFTITL 2 HUMAN HTRA1 AND HTRA3.REF PROTEIN SCI. V. 16 2454 2007REFN ISSN 0961-8368PMID 17962403DOI 10.1110/PS.073049407 Variant Set Distributions Mapped Variants
General Structure Information 3dpr VLDLR human rhinovirus 2 bound to a concatamer of the vldl receptor module v3 3.5Å AUTH J.QUEROL-AUDI,T.KONECSNI,J.POUS,O.CARUGO,I.FITA,N.VERDAGUER,AUTH 2 D.BLAASTITL MINOR GROUP HUMAN RHINOVIRUS-RECEPTOR INTERACTIONS: GEOMETRYTITL 2 OF MULTIMODULAR ATTACHMENT AND BASIS OF RECOGNITIONREF FEBS LETT. V. 583 235 2009REFN ISSN 0014-5793PMID 19073182DOI 10.1016/J.FEBSLET.2008.12.014 Variant Set Distributions Mapped Variants
General Structure Information 4lcj CTBP2 ctbp2 in complex with substrate mtob 2.86Å AUTH B.J.HILBERT,S.R.GROSSMANN,C.A.SCHIFFER,W.E.ROYERTITL CRYSTAL STRUCTURES OF HUMAN CTBP IN COMPLEX WITH SUBSTRATETITL 2 MTOB REVEAL ACTIVE SITE FEATURES USEFUL FOR INHIBITORTITL 3 DESIGN.REF FEBS LETT. V. 588 1743 2014REFN ISSN 0014-5793PMID 24657618DOI 10.1016/J.FEBSLET.2014.03.026 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 3zke DYNLL1 structure of lc8 in complex with nek9 peptide 2.2Å AUTH P.GALLEGO,A.VELAZQUEZ-CAMPOY,L.REGUE,J.ROIG,D.REVERTERTITL STRUCTURAL ANALYSIS OF THE REGULATION OF THE DYNLL/LC8TITL 2 BINDING TO NEK9 BY PHOSPHORYLATIONREF J.BIOL.CHEM. V. 288 12283 2013REFN ISSN 0021-9258PMID 23482567DOI 10.1074/JBC.M113.459149 Variant Set Distributions Mapped Variants