Assessment of Structural Intolerance and Durability
General Structure Information 2ev8 MPP1 solution structure of the erythroid p55 pdz domain -1.0Å AUTH H.KUSUNOKI,T.KOHNOTITL SOLUTION STRUCTURE OF HUMAN ERYTHROID P55 PDZTITL 2 DOMAINREF PROTEINS V. 64 804 2006REFN ISSN 0887-3585PMID 16741958DOI 10.1002/PROT.21028 Variant Set Distributions Mapped Variants
General Structure Information 4hb4 RAN crystal structure of crm1 inhibitor leptomycin b in complex with crm1(537dltvk541/glceq)-ran-ranbp1 2.05Å AUTH Q.SUN,Y.P.CARRASCO,Y.HU,X.GUO,H.MIRZAEI,J.MACMILLAN,AUTH 2 Y.M.CHOOKTITL NUCLEAR EXPORT INHIBITION THROUGH COVALENT CONJUGATION ANDTITL 2 HYDROLYSIS OF LEPTOMYCIN B BY CRM1.REF PROC.NATL.ACAD.SCI.USA V. 110 1303 2013REFN ISSN 0027-8424PMID 23297231DOI 10.1073/PNAS.1217203110 Variant Set Distributions Mapped Variants
General Structure Information 2of5 CRADD oligomeric death domain complex 3.2Å AUTH H.H.PARK,E.LOGETTE,S.RAUNSER,S.CUENIN,T.WALZ,J.TSCHOPP,H.WUTITL DEATH DOMAIN ASSEMBLY MECHANISM REVEALED BY CRYSTALTITL 2 STRUCTURE OF THE OLIGOMERIC PIDDOSOME CORE COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 128 533 2007REFN ISSN 0092-8674PMID 17289572DOI 10.1016/J.CELL.2007.01.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2cr4 SH3BP2 solution structure of the sh2 domain of human sh3bp2 protein -1.0Å AUTH R.HATTA,T.TOMIZAWA,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH2 DOMAIN OF HUMANTITL 2 SH3BP2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3tso RAB25 structure of the cancer associated rab25 protein in complex with fip2 1.8Å AUTH S.ODA,P.Y.LALL,M.W.MCCAFFREY,A.R.KHANTITL STRUCTURE OF THE CANCER ASSOCIATED RAB25 PROTEIN IN COMPLEXTITL 2 WITH FIP2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3bg0 SEC13 architecture of a coat for the nuclear pore membrane 3.15Å AUTH K.C.HSIA,P.STAVROPOULOS,G.BLOBEL,A.HOELZTITL ARCHITECTURE OF A COAT FOR THE NUCLEAR PORETITL 2 MEMBRANE.REF CELL(CAMBRIDGE,MASS.) V. 131 1313 2007REFN ISSN 0092-8674PMID 18160040DOI 10.1016/J.CELL.2007.11.038 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1wyx BCAR1 the crystal structure of the p130cas sh3 domain at 1.1 a resolution 1.14Å AUTH M.WISNIEWSKA,B.BOSSENMAIER,G.GEORGES,F.HESSE,AUTH 2 M.DANGL,K.P.KUNKELE,I.IOANNIDIS,R.HUBER,R.A.ENGHTITL THE 1.1 A RESOLUTION CRYSTAL STRUCTURE OF THETITL 2 P130CAS SH3 DOMAIN AND RAMIFICATIONS FOR LIGANDTITL 3 SELECTIVITYREF J.MOL.BIOL. V. 347 1005 2005REFN ISSN 0022-2836PMID 15784259DOI 10.1016/J.JMB.2005.02.017 Variant Set Distributions Mapped Variants
General Structure Information 3sh5 HSPG2 calcium-bound laminin g like domain 3 from human perlecan 2.8Å AUTH B.VAN LE,H.KIM,J.CHOI,J.H.KIM,M.J.HAHN,C.LEE,K.K.KIM,AUTH 2 H.Y.HWANGTITL CRYSTAL STRUCTURE OF THE LG3 DOMAIN OF ENDOREPELLIN, ANTITL 2 ANGIOGENESIS INHIBITOR.REF J.MOL.BIOL. V. 414 231 2011REFN ISSN 0022-2836PMID 21996443DOI 10.1016/J.JMB.2011.09.048 Variant Set Distributions Mapped Variants
General Structure Information 2fju PLCB2 activated rac1 bound to its effector phospholipase c beta 2 2.2Å AUTH M.R.JEZYK,J.T.SNYDER,S.GERSHBERG,D.K.WORTHYLAKE,AUTH 2 T.K.HARDEN,J.SONDEKTITL CRYSTAL STRUCTURE OF RAC1 BOUND TO ITS EFFECTORTITL 2 PHOSPHOLIPASE C-BETA2.REF NAT.STRUCT.MOL.BIOL. V. 13 1135 2006REFN ISSN 1545-9993PMID 17115053DOI 10.1038/NSMB1175 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1pt6 ITGA1 i domain from human integrin alpha1-beta1 1.87Å AUTH Y.NYMALM,J.S.PURANEN,T.K.M.NYHOLM,J.KAPYLA,H.KIDRON,AUTH 2 T.T.AIRENNE,J.HEINO,J.P.SLOTTE,M.S.JOHNSON,T.A.SALMINENTITL JARARHAGIN-DERIVED RKKH PEPTIDES INDUCE STRUCTURAL CHANGESTITL 2 IN ALPHA1I DOMAIN OF HUMAN INTEGRIN ALPHA1BETA1.REF J.BIOL.CHEM. V. 279 7962 2004REFN ISSN 0021-9258PMID 14660600DOI 10.1074/JBC.M312912200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants