Assessment of Structural Intolerance and Durability
General Structure Information 2dis RBM47 solution structure of the rrm domain of unnamed protein product -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RRM DOMAIN OF UNNAMEDTITL 2 PROTEIN PRODUCTREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2amy PMM2 x-ray structure of human phosphomannomutase 2 (pmm2) 2.09Å AUTH CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS (CESG)TITL X-RAY STRUCTURE OF HUMAN PHOSPHOMANNOMUTASE 2 (PMM2)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2zg2 SIGLEC5 crystal structure of two n-terminal domains of native siglec-5 2.85Å AUTH M.A.ZHURAVLEVA,K.TRANDEM,P.D.SUNTITL STRUCTURAL IMPLICATIONS OF SIGLEC-5-MEDIATEDTITL 2 SIALOGLYCAN RECOGNITIONREF J.MOL.BIOL. V. 375 437 2008REFN ISSN 0022-2836PMID 18022638DOI 10.1016/J.JMB.2007.10.009 Variant Set Distributions Mapped Variants
General Structure Information 3gkh NPC1 npc1(ntd) 1.81Å AUTH H.J.KWON,L.ABI-MOSLEH,M.L.WANG,J.DEISENHOFER,J.L.GOLDSTEIN,AUTH 2 M.S.BROWN,R.E.INFANTETITL STRUCTURE OF N-TERMINAL DOMAIN OF NPC1 REVEALS DISTINCTTITL 2 SUBDOMAINS FOR BINDING AND TRANSFER OF CHOLESTEROL.REF CELL(CAMBRIDGE,MASS.) V. 137 1213 2009REFN ISSN 0092-8674PMID 19563754DOI 10.1016/J.CELL.2009.03.049 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3b6v KIF3C crystal structure of the motor domain of human kinesin family member 3c in complex with adp 2.7Å AUTH H.ZHU,W.TEMPEL,Y.SHEN,R.LANDRY,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,H.PARKTITL MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER 3C IN COMPLEXTITL 2 WITH ADP.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2wfq DHH crystal structure of the n-terminal signalling domain of human dhh without calcium 1.85Å AUTH B.BISHOP,A.R.ARICESCU,K.HARLOS,C.A.OCALLAGHAN,E.Y.JONES,AUTH 2 C.SIEBOLDTITL STRUCTURAL INSIGHTS INTO HEDGEHOG LIGAND SEQUESTRATION BYTITL 2 THE HUMAN HEDGEHOG-INTERACTING PROTEIN HIPREF NAT.STRUCT.MOL.BIOL. V. 16 698 2009REFN ISSN 1545-9993PMID 19561611DOI 10.1038/NSMB.1607 Variant Set Distributions Mapped Variants
General Structure Information 2ep8 PES1 solution structure of the brct domain from human pescadillo homolog 1 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE BRCT DOMAIN FROM HUMANTITL 2 PESCADILLO HOMOLOG 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1gh2 TXNL1 crystal structure of the catalytic domain of a new human thioredoxin-like protein 2.22Å AUTH J.JIN,X.CHEN,Y.ZHOU,M.BARTLAM,Q.GUO,Y.LIU,Y.SUN,AUTH 2 Y.GAO,S.YE,G.LI,Z.RAO,B.QIANG,J.YUANTITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF ATITL 2 HUMAN THIOREDOXIN-LIKE PROTEIN.REF EUR.J.BIOCHEM. V. 269 2060 2002REFN ISSN 0014-2956PMID 11985582DOI 10.1046/J.1432-1033.2002.02844.X Variant Set Distributions Mapped Variants
General Structure Information 4boc POLRMT structure of mitochondrial rna polymerase elongation complex 2.65Å AUTH K.SCHWINGHAMMER,A.C.M.CHEUNG,Y.I.MOROZOV,K.AGARONYAN,AUTH 2 D.TEMIAKOV,P.CRAMERTITL STRUCTURE OF HUMAN MITOCHONDRIAL RNA POLYMERASE ELONGATIONTITL 2 COMPLEXREF NAT.STRUCT.MOL.BIOL. V. 20 1298 2013REFN ISSN 1545-9993PMID 24096365DOI 10.1038/NSMB.2683 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1zjk MASP2 crystal structure of the zymogen catalytic region of human masp-2 2.18Å AUTH P.GAL,V.HARMAT,A.KOCSIS,T.BIAN,L.BARNA,G.AMBRUS,B.VEGH,AUTH 2 J.BALCZER,R.B.SIM,G.NARAY-SZABO,P.ZAVODSZKYTITL A TRUE AUTOACTIVATING ENZYME: STRUCTURAL INSIGHT INTOTITL 2 MANNOSE-BINDING LECTIN-ASSOCIATED SERINE PROTEASE-2TITL 3 ACTIVATIONSREF J.BIOL.CHEM. V. 280 33435 2005REFN ISSN 0021-9258PMID 16040602DOI 10.1074/JBC.M506051200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]