General Structure Information
| PDB ID | 3b6v |
| HGNC Gene Label(s) | KIF3C |
| Structure Name | crystal structure of the motor domain of human kinesin family member 3c in complex with adp |
| Resolution | 2.7Å |
| Reference | AUTH H.ZHU,W.TEMPEL,Y.SHEN,R.LANDRY,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,H.PARKTITL MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER 3C IN COMPLEXTITL 2 WITH ADP.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 306 |
| Number Of SNVs | 49 |
| Number Of Permutations | 11037 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.258 |
| p-value | 0.0 |
COSMIC
| Number Of Residues | 306 |
| Number Of SNVs | 5 |
| Number Of Permutations | 113 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.2 |
| p-value | 0.412 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 49 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.457 |
| p-value | 0.023 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
