Assessment of Structural Intolerance and Durability
General Structure Information 4fo9 PIAS2 crystal structure of the e3 sumo ligase pias2 2.39Å AUTH J.HU,A.DONG,E.DOBROVETSKY,W.TEMPEL,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,Y.TONG,STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF THE E3 SUMO LIGASE PIAS2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3rzu STAMBP the crystal structure of the catalytic domain of amsh 2.5Å AUTH C.W.DAVIES,L.N.PAUL,M.I.KIM,C.DASTITL STRUCTURAL AND THERMODYNAMIC COMPARISON OF THE CATALYTICTITL 2 DOMAIN OF AMSH AND AMSH-LP: NEARLY IDENTICAL FOLD BUTTITL 3 DIFFERENT STABILITY.REF J.MOL.BIOL. V. 413 416 2011REFN ISSN 0022-2836PMID 21888914DOI 10.1016/J.JMB.2011.08.029 Variant Set Distributions Mapped Variants
General Structure Information 2cpc OBSL1 solution structure of rsgi ruh-030, an ig like domain from human cdna -1.0Å AUTH A.Z.M.RUHUL MOMEN,H.ONUKI,H.HIROTA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-030, AN IG LIKETITL 2 DOMAIN FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dib FLNB solution structure of the 11th filamin domain from human filamin-b -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 11TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN-BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1v66 PIAS1 solution structure of human p53 binding domain of pias-1 -1.0Å AUTH S.OKUBO,F.HARA,Y.TSUCHIDA,S.SHIMOTAKAHARA,S.SUZUKI,AUTH 2 H.HATANAKA,S.YOKOYAMA,H.TANAKA,H.YASUDA,H.SHINDOTITL NMR STRUCTURE OF THE N-TERMINAL DOMAIN OF SUMOTITL 2 LIGASE PIAS1 AND ITS INTERACTION WITH TUMORTITL 3 SUPPRESSOR P53 AND A/T-RICH DNA OLIGOMERSREF J.BIOL.CHEM. V. 279 31455 2004REFN ISSN 0021-9258PMID 15133049DOI 10.1074/JBC.M403561200 Variant Set Distributions Mapped […]
General Structure Information 2m16 PSIP1 p75/ledgf pwwp domain -1.0Å AUTH J.O.EIDAHL,B.L.CROWE,J.A.NORTH,C.J.MCKEE,N.SHKRIABAI,L.FENG,AUTH 2 M.PLUMB,R.L.GRAHAM,R.J.GORELICK,S.HESS,M.G.POIRIER,AUTH 3 M.P.FOSTER,M.KVARATSKHELIATITL STRUCTURAL BASIS FOR HIGH-AFFINITY BINDING OF LEDGF PWWP TOTITL 2 MONONUCLEOSOMES.REF NUCLEIC ACIDS RES. V. 41 3924 2013REFN ISSN 0305-1048PMID 23396443DOI 10.1093/NAR/GKT074 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2zne PDCD6 crystal structure of zn2+-bound form of des3-23alg-2 complexed with alix abs peptide 2.2Å AUTH H.SUZUKI,M.KAWASAKI,T.INUZUKA,M.OKUMURA,T.KAKIUCHI,AUTH 2 H.SHIBATA,S.WAKATSUKI,M.MAKITITL STRUCTURAL BASIS FOR CA(2+)-DEPENDENT FORMATION OFTITL 2 ALG-2/ALIX PEPTIDE COMPLEX: CA(2+)/EF3-DRIVENTITL 3 ARGININE SWITCH MECHANISMREF STRUCTURE V. 16 1562 2008REFN ISSN 0969-2126PMID 18940611DOI 10.1016/J.STR.2008.07.012 Variant Set Distributions Mapped Variants
General Structure Information 1m7k BAG4 solution structure of the sodd bag domain -1.0Å AUTH C.BROCKMANN,D.LEITNER,D.LABUDDE,A.DIEHL,V.SIEVERT,AUTH 2 K.BUESSOW,R.KUHNE,H.OSCHKINATTITL THE SOLUTION STRUCTURE OF THE SODD BAG DOMAINTITL 2 REVEALS ADDITIONAL ELECTROSTATIC INTERACTIONS INTITL 3 THE HSP70 COMPLEXES OF SODD SUBFAMILY BAG DOMAINSREF FEBS LETT. V. 558 101 2004REFN ISSN 0014-5793PMID 14759524DOI 10.1016/S0014-5793(03)01490-X Variant Set Distributions Mapped Variants
General Structure Information 1yck PGLYRP1 crystal structure of human peptidoglycan recognition protein (pgrp-s) 1.7Å AUTH R.GUAN,Q.WANG,E.J.SUNDBERG,R.A.MARIUZZATITL CRYSTAL STRUCTURE OF HUMAN PEPTIDOGLYCANTITL 2 RECOGNITION PROTEIN S (PGRP-S) AT 1.70 ATITL 3 RESOLUTION.REF J.MOL.BIOL. V. 347 683 2005REFN ISSN 0022-2836PMID 15769462DOI 10.1016/J.JMB.2005.01.070 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3t5i PDE6D structure of fully modified farnesylated rheb peptide in complex with pde6d 2.1Å AUTH S.A.ISMAIL,Y.X.CHEN,A.RUSINOVA,A.CHANDRA,M.BIERBAUM,AUTH 2 L.GREMER,G.TRIOLA,H.WALDMANN,P.I.BASTIAENS,A.WITTINGHOFERTITL ARL2-GTP AND ARL3-GTP REGULATE A GDI-LIKE TRANSPORT SYSTEMTITL 2 FOR FARNESYLATED CARGO.REF NAT.CHEM.BIOL. V. 7 942 2011REFN ISSN 1552-4450PMID 22002721DOI 10.1038/NCHEMBIO.686 Variant Set Distributions Mapped Variants