2YD8.A | PTPRF

General Structure Information 2yd8 PTPRF crystal structure of the n-terminal ig1-2 module of human receptor protein tyrosine phosphatase lar in complex with sucrose octasulphate 2.05Å AUTH C.H.COLES,Y.SHEN,A.P.TENNEY,C.SIEBOLD,G.C.SUTTON,W.LU,AUTH 2 J.T.GALLAGHER,E.Y.JONES,J.G.FLANAGAN,A.R.ARICESCUTITL PROTEOGLYCAN-SPECIFIC MOLECULAR SWITCH FOR RPTP SIGMATITL 2 CLUSTERING AND NEURONAL EXTENSION.REF SCIENCE V. 332 484 2011REFN ISSN 0036-8075PMID 21454754DOI 10.1126/SCIENCE.1200840 Variant Set Distributions Mapped Variants

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1HRA.A | RARB

General Structure Information 1hra RARB the solution structure of the human retinoic acid receptor- beta dna-binding domain -1.0Å AUTH R.M.KNEGTEL,M.KATAHIRA,J.G.SCHILTHUIS,A.M.BONVIN,AUTH 2 R.BOELENS,D.EIB,P.T.VAN DER SAAG,R.KAPTEINTITL THE SOLUTION STRUCTURE OF THE HUMAN RETINOIC ACIDTITL 2 RECEPTOR-BETA DNA-BINDING DOMAIN.REF J.BIOMOL.NMR V. 3 1 1993REFN ISSN 0925-2738PMID 8383553DOI 10.1007/BF00242472 Variant Set Distributions Mapped Variants

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3KLT.B | VIM

General Structure Information 3klt VIM crystal structure of a vimentin fragment 2.7Å AUTH S.NICOLET,H.HERRMANN,U.AEBI,S.V.STRELKOVTITL ATOMIC STRUCTURE OF VIMENTIN COIL 2.REF J.STRUCT.BIOL. V. 170 369 2010REFN ISSN 1047-8477PMID 20176112DOI 10.1016/J.JSB.2010.02.012 Variant Set Distributions Mapped Variants

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3BG3.A | PC

General Structure Information 3bg3 PC crystal structure of human pyruvate carboxylase (missing the biotin carboxylase domain at the n-terminus) 2.8Å AUTH S.XIANG,L.TONGTITL CRYSTAL STRUCTURES OF HUMAN AND STAPHYLOCOCCUSTITL 2 AUREUS PYRUVATE CARBOXYLASE AND MOLECULAR INSIGHTSTITL 3 INTO THE CARBOXYLTRANSFER REACTION.REF NAT.STRUCT.MOL.BIOL. V. 15 295 2008REFN ISSN 1545-9993PMID 18297087DOI 10.1038/NSMB.1393 Variant Set Distributions Ripley’s K Analysis […]

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2ODE.C | GNAI3

General Structure Information 2ode GNAI3 crystal structure of the heterodimeric complex of human rgs8 and activated gi alpha 3 1.9Å AUTH M.SOUNDARARAJAN,F.S.WILLARD,A.J.KIMPLE,A.P.TURNBULL,AUTH 2 L.J.BALL,G.A.SCHOCH,C.GILEADI,O.Y.FEDOROV,E.F.DOWLER,AUTH 3 V.A.HIGMAN,S.Q.HUTSELL,M.SUNDSTROM,D.A.DOYLE,D.P.SIDEROVSKITITL STRUCTURAL DIVERSITY IN THE RGS DOMAIN AND ITS INTERACTIONTITL 2 WITH HETEROTRIMERIC G PROTEIN ALPHA-SUBUNITS.REF PROC.NATL.ACAD.SCI.USA V. 105 6457 2008REFN ISSN 0027-8424PMID 18434541DOI 10.1073/PNAS.0801508105 Variant Set Distributions Mapped Variants

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2CSO.A | PLEK

General Structure Information 2cso PLEK solution structure of the dep domain of human pleckstrin -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE DEP DOMAIN OF HUMANTITL 2 PLECKSTRINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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3B97.B | ENO1

General Structure Information 3b97 ENO1 crystal structure of human enolase 1 2.2Å AUTH H.J.KANG,S.K.JUNG,S.J.KIM,S.J.CHUNGTITL STRUCTURE OF HUMAN ALPHA-ENOLASE (HENO1), ATITL 2 MULTIFUNCTIONAL GLYCOLYTIC ENZYME.REF ACTA CRYSTALLOGR.,SECT.D V. 64 651 2008REFN ISSN 0907-4449PMID 18560153DOI 10.1107/S0907444908008561 Variant Set Distributions Mapped Variants

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2OUJ.A | THBS1

General Structure Information 2ouj THBS1 the crystal structure of the thrombospondin-1 n-terminal domain in complex with fractionated heparin dp8 1.9Å AUTH K.TAN,M.DUQUETTE,J.H.LIU,K.SHANMUGASUNDARAM,AUTH 2 A.JOACHIMIAK,J.T.GALLAGHER,A.C.RIGBY,J.H.WANG,AUTH 3 J.LAWLERTITL HEPARIN-INDUCED CIS- AND TRANS-DIMERIZATION MODESTITL 2 OF THE THROMBOSPONDIN-1 N-TERMINAL DOMAIN.REF J.BIOL.CHEM. V. 283 3932 2008REFN ISSN 0021-9258PMID 18065761DOI 10.1074/JBC.M705203200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]

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2V5O.A | IGF2R

General Structure Information 2v5o IGF2R structure of human igf2r domains 11-14 2.91Å AUTH J.BROWN,C.DELAINE,O.J.ZACCHEO,C.SIEBOLD,R.J.GILBERT,AUTH 2 G.VAN BOXEL,A.DENLEY,J.C.WALLACE,A.B.HASSAN,B.E.FORBES,AUTH 3 E.Y.JONESTITL STRUCTURE AND FUNCTIONAL ANALYSIS OF THE IGF-II/IGF2RTITL 2 INTERACTIONREF EMBO J. V. 27 265 2008REFN ISSN 0261-4189PMID 18046459DOI 10.1038/SJ.EMBOJ.7601938 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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1HDP.A | POU2F2

General Structure Information 1hdp POU2F2 solution structure of a pou-specific homeodomain: 3d-nmr studies of human b-cell transcription factor oct-2 -1.0Å AUTH M.SIVARAJA,M.C.BOTFIELD,M.MUELLER,A.JANCSO,AUTH 2 M.A.WEISSTITL SOLUTION STRUCTURE OF A POU-SPECIFIC HOMEODOMAIN:TITL 2 3D-NMR STUDIES OF HUMAN B-CELL TRANSCRIPTIONTITL 3 FACTOR OCT-2.REF BIOCHEMISTRY V. 33 9845 1994REFN ISSN 0006-2960PMID 7914745DOI 10.1021/BI00199A005 Variant Set Distributions Mapped Variants

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